8DXP
| Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 3 | Descriptor: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | Authors: | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | Deposit date: | 2022-08-02 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
|
|
8DXO
| Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 2 | Descriptor: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | Authors: | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | Deposit date: | 2022-08-02 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
|
|
8DXN
| Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 1 | Descriptor: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | Authors: | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | Deposit date: | 2022-08-02 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
|
|
8DXR
| Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 5 | Descriptor: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | Authors: | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | Deposit date: | 2022-08-02 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
|
|
2PBJ
| GSH-heme bound microsomal prostaglandin E synthase | Descriptor: | CHLORIDE ION, GLUTATHIONE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Takusagawa, F, Yamada, T. | Deposit date: | 2007-03-28 | Release date: | 2008-02-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | PGH2 degradation pathway catalyzed by GSH-heme complex bound microsomal prostaglandin E2 synthase type 2: the first example of a dual-function enzyme. Biochemistry, 46, 2007
|
|
5XOF
| Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide I | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Paired immunoglobulin-like type 2 receptor alpha, Peptide from Nitric oxide synthase, ... | Authors: | Furukawa, A, Kakita, K, Yamada, T, Ishizuka, M, Sakamoto, J, Hatori, N, Maeda, N, Ohsaka, F, Saitoh, T, Nomura, T, Kuroki, K, Nambu, H, Arase, H, Matsunaga, H, Anada, M, Ose, T, Hashimoto, S, Maenaka, K. | Deposit date: | 2017-05-28 | Release date: | 2017-10-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.963 Å) | Cite: | Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILR alpha immune cell receptor. J. Biol. Chem., 292, 2017
|
|
5XO2
| Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide II | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2,4-dideoxy-alpha-D-xylo-hexopyranose, Paired immunoglobulin-like type 2 receptor alpha, Peptide from Envelope glycoprotein B | Authors: | Furukawa, A, Kakita, K, Yamada, T, Ishizuka, M, Sakamoto, J, Hatori, N, Maeda, N, Ohsaka, F, Saitoh, T, Nomura, T, Kuroki, K, Nambu, H, Arase, H, Matsunaga, S, Anada, M, Ose, T, Hashimoto, S, Maenaka, K. | Deposit date: | 2017-05-25 | Release date: | 2017-10-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILR alpha immune cell receptor. J. Biol. Chem., 292, 2017
|
|
3FHP
| A neutron crystallographic analysis of a porcine 2Zn insulin at 2.0 A resolution | Descriptor: | Insulin, ZINC ION | Authors: | Iwai, W, Kurihara, K, Yamada, T, Kobayashi, Y, Ohnishi, Y, Tanaka, I, Takahashi, H, Niimura, N. | Deposit date: | 2008-12-09 | Release date: | 2009-10-20 | Last modified: | 2023-11-01 | Method: | NEUTRON DIFFRACTION (2 Å) | Cite: | A neutron crystallographic analysis of T6 porcine insulin at 2.1 A resolution Acta Crystallogr.,Sect.D, 65, 2009
|
|
6L9C
| Neutron structure of copper amine oxidase from Arthrobacter glibiformis at pD 7.4 | Descriptor: | COPPER (II) ION, Phenylethylamine oxidase, SODIUM ION | Authors: | Murakawa, T, Kurihara, K, Shoji, M, Shibazaki, C, Sunami, T, Tamada, T, Yano, N, Yamada, T, Kusaka, K, Suzuki, M, Shigeta, Y, Kuroki, R, Hayashi, H, Yano, Y, Tanizawa, K, Adachi, M, Okajima, T. | Deposit date: | 2019-11-08 | Release date: | 2020-04-29 | Last modified: | 2023-11-22 | Method: | NEUTRON DIFFRACTION (1.14 Å), X-RAY DIFFRACTION | Cite: | Neutron crystallography of copper amine oxidase reveals keto/enolate interconversion of the quinone cofactor and unusual proton sharing. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
1RG9
| S-Adenosylmethionine synthetase complexed with SAM and PPNP | Descriptor: | (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Komoto, J, Yamada, T, Takata, Y, Markham, G.D, Takusagawa, F. | Deposit date: | 2003-11-11 | Release date: | 2004-03-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the S-adenosylmethionine synthetase ternary complex: a novel catalytic mechanism of s-adenosylmethionine synthesis from ATP and MET. Biochemistry, 43, 2004
|
|
7YF6
| Crystal structure of HIV-1 protease in complex with macrocyclic peptide | Descriptor: | MAGNESIUM ION, Macrocyclic Peptide, Protease | Authors: | Kusumoto, Y, Sato, S, Yamada, T, Kozono, I, Nakata, Z, Asada, N, Mitsuki, S, Wakasa-Morimoto, C, Tohru, M, Watanabe, A, Hayashi, K, Mikamiyama, H. | Deposit date: | 2022-07-07 | Release date: | 2022-11-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Highly Potent and Oral Macrocyclic Peptides as a HIV-1 Protease Inhibitor: mRNA Display-Derived Hit-to-Lead Optimization. Acs Med.Chem.Lett., 13, 2022
|
|
7YQS
| Neutron structure of a L-rhamnose-alpha-1,4-D-glucuronate lyase from Fusarium oxysporum 12S, L-Rha complex | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Yano, N, Kondo, T, Kusaka, K, Yamada, T, Arakawa, T, Sakamoto, T, Fushinobu, S. | Deposit date: | 2022-08-08 | Release date: | 2023-08-09 | Last modified: | 2024-03-27 | Method: | NEUTRON DIFFRACTION (1.25 Å), X-RAY DIFFRACTION | Cite: | Charge neutralization and beta-elimination cleavage mechanism of family 42 L-rhamnose-alpha-1,4-D-glucuronate lyase revealed using neutron crystallography. J.Biol.Chem., 300, 2024
|
|
3GNE
| Crystal structure of alginate lyase vAL-1 from Chlorella virus | Descriptor: | CITRATE ANION, GLYCEROL, VAL-1 | Authors: | Ogura, K, Yamasaki, M, Hashidume, T, Yamada, T, Mikami, B, Hashimoto, W, Murata, K. | Deposit date: | 2009-03-17 | Release date: | 2009-10-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal structure of family 14 polysaccharide lyase with pH-dependent modes of action J.Biol.Chem., 284, 2009
|
|
5AX9
| Crystal structure of the kinase domain of human TRAF2 and NCK-interacting protein kinase in complex with compund 9 | Descriptor: | 4-methoxy-3-[2-[(3-methoxy-4-morpholin-4-yl-phenyl)amino]pyridin-4-yl]benzenecarbonitrile, SULFATE ION, TRAF2 and NCK-interacting protein kinase | Authors: | Ohbayashi, N, Kukimoto-Niino, M, Yamada, T, Shirouzu, M. | Deposit date: | 2015-07-21 | Release date: | 2016-07-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | TNIK inhibition abrogates colorectal cancer stemness Nat Commun, 7, 2016
|
|
5D7A
| Crystal structure of the kinase domain of TRAF2 and NCK-interacting protein kinase with NCB-0846 | Descriptor: | SULFATE ION, TRAF2 and NCK-interacting protein kinase, cis-4-{[2-(1H-benzimidazol-5-ylamino)quinazolin-8-yl]oxy}cyclohexanol | Authors: | Ohbayashi, N, Kukimoto-Niino, M, Yamada, T, Shirouzu, M. | Deposit date: | 2015-08-13 | Release date: | 2016-08-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | TNIK inhibition abrogates colorectal cancer stemness Nat Commun, 7, 2016
|
|
5CWZ
| |
6IHX
| Crystal Structure Analysis of bovine Hemoglobin modified by SNP | Descriptor: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | Authors: | Kihira, K, Morita, Y, Yamada, T, Kureishi, M, Komatsu, T. | Deposit date: | 2018-10-03 | Release date: | 2018-12-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Quaternary Structure Analysis of a Hemoglobin Core in Hemoglobin-Albumin Cluster. J Phys Chem B, 122, 2018
|
|
6KLW
| Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with long stem | Descriptor: | CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib | Authors: | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | Deposit date: | 2019-07-30 | Release date: | 2020-01-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex. Nat.Struct.Mol.Biol., 27, 2020
|
|
6KLX
| Pore structure of Iota toxin binding component (Ib) | Descriptor: | CALCIUM ION, Iota toxin component Ib | Authors: | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | Deposit date: | 2019-07-30 | Release date: | 2020-01-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex. Nat.Struct.Mol.Biol., 27, 2020
|
|
6KLO
| Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with short stem | Descriptor: | CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib | Authors: | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | Deposit date: | 2019-07-30 | Release date: | 2020-01-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex. Nat.Struct.Mol.Biol., 27, 2020
|
|
1RY8
| Prostaglandin F synthase complexed with NADPH and rutin | Descriptor: | Aldo-keto reductase family 1 member C3, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RUTIN | Authors: | Komoto, J, Yamada, T, Watanabe, K, Takusagawa, F. | Deposit date: | 2003-12-19 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Crystal structure of human prostaglandin F synthase (AKR1C3). Biochemistry, 43, 2004
|
|
1RY0
| Structure of prostaglandin F synthase with prostaglandin D2 | Descriptor: | Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROSTAGLANDIN D2 | Authors: | Komoto, J, Yamada, T, Watanabe, K, Takusagawa, F. | Deposit date: | 2003-12-19 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Crystal structure of human prostaglandin F synthase (AKR1C3). Biochemistry, 43, 2004
|
|
1LZ5
| STRUCTURAL AND FUNCTIONAL ANALYSES OF THE ARG-GLY-ASP SEQUENCE INTRODUCED INTO HUMAN LYSOZYME | Descriptor: | CHLORIDE ION, HUMAN LYSOZYME | Authors: | Matsushima, M, Inaka, K, Yamada, T, Sekiguchi, K, Kikuchi, M. | Deposit date: | 1993-02-03 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and functional analyses of the Arg-Gly-Asp sequence introduced into human lysozyme. J.Biol.Chem., 268, 1993
|
|
1LZ6
| STRUCTURAL AND FUNCTIONAL ANALYSES OF THE ARG-GLY-ASP SEQUENCE INTRODUCED INTO HUMAN LYSOZYME | Descriptor: | CHLORIDE ION, HUMAN LYSOZYME | Authors: | Matsushima, M, Inaka, K, Yamada, T, Sekiguchi, K, Kikuchi, M. | Deposit date: | 1993-02-03 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and functional analyses of the Arg-Gly-Asp sequence introduced into human lysozyme. J.Biol.Chem., 268, 1993
|
|
1XCJ
| Guanidinoacetate methyltransferase containing S-adenosylhomocysteine and guanidinoacetate | Descriptor: | GUANIDINO ACETATE, Guanidinoacetate N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Komoto, J, Yamada, T, Takata, Y, Takusagawa, F. | Deposit date: | 2004-09-02 | Release date: | 2004-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Catalytic mechanism of guanidinoacetate methyltransferase: crystal structures of guanidinoacetate methyltransferase ternary complexes. Biochemistry, 43, 2004
|
|