5WRG
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![BU of 5wrg by Molmil](/molmil-images/mine/5wrg) | SARS-CoV spike glycoprotein | Descriptor: | Spike glycoprotein | Authors: | Gui, M, Song, W, Xiang, Y, Wang, X. | Deposit date: | 2016-12-01 | Release date: | 2017-01-11 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding. Cell Res., 27, 2017
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5KIJ
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![BU of 5kij by Molmil](/molmil-images/mine/5kij) | Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase and Man9GlcNAc2-PA complex | Descriptor: | 1,4-BUTANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, ... | Authors: | Karaveg, K, Xiang, Y, Moremen, K.W. | Deposit date: | 2016-06-16 | Release date: | 2017-05-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.649 Å) | Cite: | Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5KK7
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![BU of 5kk7 by Molmil](/molmil-images/mine/5kk7) | Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase T688A mutant and Thio-disaccharide substrate analog complex | Descriptor: | 1,4-BUTANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ACETATE ION, ... | Authors: | Karaveg, K, Xiang, Y, Moremen, K.W. | Deposit date: | 2016-06-21 | Release date: | 2017-05-10 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7324 Å) | Cite: | Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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2ISO
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![BU of 2iso by Molmil](/molmil-images/mine/2iso) | Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-difluoromethylene triphosphate | Descriptor: | 2'-DEOXY-5'-O-[({[DIFLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL}OXY)(HYDROXY)PHOSPHORYL]GUANOSINE, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ... | Authors: | Sucato, C.A, Upton, T.G, Kashemirov, B.A, Martinek, V, Xiang, Y, Beard, W.A. | Deposit date: | 2006-10-18 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Modifying the beta,gamma Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of DNA Polymerase beta. Biochemistry, 46, 2007
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2ISP
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![BU of 2isp by Molmil](/molmil-images/mine/2isp) | Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-methylene triphosphate | Descriptor: | 2'-DEOXY-5'-O-(HYDROXY{[HYDROXY(PHOSPHONOMETHYL)PHOSPHORYL]OXY}PHOSPHORYL)GUANOSINE, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ... | Authors: | Sucato, C.A, Upton, T.G, Kashemirov, B.A, Martinek, V, Xiang, Y, Beard, W.A. | Deposit date: | 2006-10-18 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Modifying the beta,gamma Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of DNA Polymerase beta. Biochemistry, 46, 2007
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7DM2
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![BU of 7dm2 by Molmil](/molmil-images/mine/7dm2) | crystal structure of the M. tuberculosis phosphate ABC transport receptor PstS-1 in complex with Fab p4-170 | Descriptor: | PHOSPHATE ION, Phosphate-binding protein PstS 1, heavy chain, ... | Authors: | Ma, B, Freund, N, Xiang, Y. | Deposit date: | 2020-12-01 | Release date: | 2020-12-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Human antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis. Nat Commun, 12, 2021
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7DM1
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![BU of 7dm1 by Molmil](/molmil-images/mine/7dm1) | crystal structure of the M.tuberculosis phosphate ABC transport receptor PstS-1 in complex with Fab p4-36 | Descriptor: | PHOSPHATE ION, Phosphate-binding protein PstS 1, heavy chain, ... | Authors: | Ma, B, Freund, N, Xiang, Y. | Deposit date: | 2020-12-01 | Release date: | 2020-12-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Human antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis. Nat Commun, 12, 2021
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4U03
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![BU of 4u03 by Molmil](/molmil-images/mine/4u03) | |
4U0M
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![BU of 4u0m by Molmil](/molmil-images/mine/4u0m) | |
1T0Z
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![BU of 1t0z by Molmil](/molmil-images/mine/1t0z) | Structure of an Excitatory Insect-specific Toxin with an Analgesic Effect on Mammalian from Scorpion Buthus martensii Karsch | Descriptor: | SULFATE ION, insect neurotoxin | Authors: | Li, C, Guan, R.-J, Xiang, Y, Zhang, Y, Wang, D.-C. | Deposit date: | 2004-04-14 | Release date: | 2004-12-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of an excitatory insect-specific toxin with an analgesic effect on mammals from the scorpion Buthus martensii Karsch. Acta Crystallogr.,Sect.D, 61, 2005
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8IGL
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![BU of 8igl by Molmil](/molmil-images/mine/8igl) | |
8IGG
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![BU of 8igg by Molmil](/molmil-images/mine/8igg) | |
1X7I
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![BU of 1x7i by Molmil](/molmil-images/mine/1x7i) | Crystal structure of the native copper homeostasis protein (cutCm) with calcium binding from Shigella flexneri 2a str. 301 | Descriptor: | CALCIUM ION, Copper homeostasis protein cutC | Authors: | Zhu, D.Y, Zhu, Y.Q, Huang, R.H, Xiang, Y, Wang, D.C. | Deposit date: | 2004-08-14 | Release date: | 2005-03-01 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the copper homeostasis protein (CutCm) from Shigella flexneri at 1.7 A resolution: The first structure of a new sequence family of TIM barrels Proteins, 58, 2004
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8IHP
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![BU of 8ihp by Molmil](/molmil-images/mine/8ihp) | Structure of Semliki Forest virus VLP in complex with the receptor VLDLR-LA3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ... | Authors: | Cao, D, Ma, B, Cao, Z, Zhang, X, Xiang, Y. | Deposit date: | 2023-02-23 | Release date: | 2023-04-12 | Last modified: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of Semliki Forest virus in complex with its receptor VLDLR. Cell, 186, 2023
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5CYW
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![BU of 5cyw by Molmil](/molmil-images/mine/5cyw) | Crystal Structure of Vaccinia Virus C7 | Descriptor: | GLYCEROL, Interferon antagonist C7 | Authors: | Krumm, B.E, Meng, X, Li, Y, Xiang, Y, Deng, J. | Deposit date: | 2015-07-30 | Release date: | 2015-11-18 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins. Proc.Natl.Acad.Sci.USA, 112, 2015
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5CZ3
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![BU of 5cz3 by Molmil](/molmil-images/mine/5cz3) | Crystal Structure of Myxoma Virus M64 | Descriptor: | BETA-MERCAPTOETHANOL, M64R | Authors: | Krumm, B.E, Meng, X, Li, Y, Xiang, Y, Deng, J. | Deposit date: | 2015-07-31 | Release date: | 2015-11-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins. Proc.Natl.Acad.Sci.USA, 112, 2015
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4XFU
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![BU of 4xfu by Molmil](/molmil-images/mine/4xfu) | Structure of IL-18 SER Mutant V | Descriptor: | Interleukin-18 | Authors: | Krumm, B.E, Meng, X, Xiang, Y, Deng, J. | Deposit date: | 2014-12-29 | Release date: | 2015-06-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystallization of interleukin-18 for structure-based inhibitor design. Acta Crystallogr.,Sect.F, 71, 2015
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4XFT
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![BU of 4xft by Molmil](/molmil-images/mine/4xft) | Structure of IL-18 SER Mutant III | Descriptor: | DIMETHYL SULFOXIDE, Interleukin-18 | Authors: | Krumm, B.E, Meng, X, Xiang, Y, Deng, J. | Deposit date: | 2014-12-29 | Release date: | 2015-06-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystallization of interleukin-18 for structure-based inhibitor design. Acta Crystallogr.,Sect.F, 71, 2015
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4XFS
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![BU of 4xfs by Molmil](/molmil-images/mine/4xfs) | Structure of IL-18 SER Mutant I | Descriptor: | DIMETHYL SULFOXIDE, GLYCEROL, Interleukin-18 | Authors: | Krumm, B.E, Meng, X, Xiang, Y, Deng, J. | Deposit date: | 2014-12-28 | Release date: | 2015-06-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Crystallization of interleukin-18 for structure-based inhibitor design. Acta Crystallogr.,Sect.F, 71, 2015
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2WZS
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![BU of 2wzs by Molmil](/molmil-images/mine/2wzs) | Structure of the Family GH92 Inverting Mannosidase BT3990 from Bacteroides thetaiotaomicron VPI-5482 in complex with Mannoimidazole | Descriptor: | (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, CALCIUM ION, GLYCEROL, ... | Authors: | Zhu, Y, Suits, M.D.L, Thompson, A, Chavan, S, Dinev, Z, Dumon, C, Smith, N, Moremen, K.W, Xiang, Y, Siriwardena, A, Williams, S.J, Gilbert, H.J, Davies, G.J. | Deposit date: | 2009-12-02 | Release date: | 2009-12-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont. Nat.Chem.Biol., 6, 2010
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7KSP
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![BU of 7ksp by Molmil](/molmil-images/mine/7ksp) | Crystal structure of hSAMD9_DBD with DNA | Descriptor: | DNA, Sterile alpha motif domain-containing protein 9 | Authors: | Peng, S, Pathak, P, Xiang, Y, Deng, J. | Deposit date: | 2020-11-23 | Release date: | 2022-01-05 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure and function of an effector domain in antiviral factors and tumor suppressors SAMD9 and SAMD9L. Proc.Natl.Acad.Sci.USA, 119, 2022
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7TA8
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![BU of 7ta8 by Molmil](/molmil-images/mine/7ta8) | NMR structure of crosslinked cyclophilin A | Descriptor: | Peptidyl-prolyl cis-trans isomerase A | Authors: | Lu, M, Toptygin, D, Xiang, Y, Shi, Y, Schwieters, C.D, Lipinski, E.C, Ahn, J, Byeon, I.-J.L, Gronenborn, A.M. | Deposit date: | 2021-12-20 | Release date: | 2022-06-01 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Magic of Linking Rings: Discovery of a Unique Photoinduced Fluorescent Protein Crosslink. J.Am.Chem.Soc., 144, 2022
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5FB5
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![BU of 5fb5 by Molmil](/molmil-images/mine/5fb5) | |
6QX7
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![BU of 6qx7 by Molmil](/molmil-images/mine/6qx7) | |
6QYJ
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![BU of 6qyj by Molmil](/molmil-images/mine/6qyj) | |