4HXJ
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![BU of 4hxj by Molmil](/molmil-images/mine/4hxj) | Crystal structure of SH3:RGT complex | Descriptor: | C-terminal 3-mer peptide from Integrin beta-3, Proto-oncogene tyrosine-protein kinase Src | Authors: | Xiao, R, Meng, G. | Deposit date: | 2012-11-11 | Release date: | 2012-11-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural framework of c-Src activation by integrin beta 3 Blood, 121, 2013
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7DSZ
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![BU of 7dsz by Molmil](/molmil-images/mine/7dsz) | Crystal structure of Amuc_1102 from Akkermansia muciniphila | Descriptor: | Amuc_1102, CHLORIDE ION | Authors: | Xiang, R, Wang, J, Wang, Y, Zhang, M, Wang, M. | Deposit date: | 2021-01-04 | Release date: | 2021-02-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Amuc_1102 fromAkkermansia muciniphilaadopts animmunoglobulin-like fold related to archaeal type IV pilus Biochem.Biophys.Res.Commun., 547, 2021
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2RJB
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![BU of 2rjb by Molmil](/molmil-images/mine/2rjb) | Crystal structure of uncharacterized protein YdcJ (SF1787) from Shigella flexneri which includes domain DUF1338. Northeast Structural Genomics Consortium target SfR276 | Descriptor: | Uncharacterized protein, ZINC ION | Authors: | Seetharaman, J, Chen, Y, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-10-14 | Release date: | 2007-10-30 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of uncharacterized protein YdcJ (SF1787) from Shigella flexneri which includes domain DUF1338. To be Published
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8JXT
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![BU of 8jxt by Molmil](/molmil-images/mine/8jxt) | Histamine-bound H4R/Gi complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | He, Y, Xia, R. | Deposit date: | 2023-07-01 | Release date: | 2024-03-20 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structural basis of ligand recognition and design of antihistamines targeting histamine H 4 receptor. Nat Commun, 15, 2024
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8JXV
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![BU of 8jxv by Molmil](/molmil-images/mine/8jxv) | Clozapine-bound H4R/Gi complex | Descriptor: | 3-chloranyl-6-(4-methylpiperazin-1-yl)-11~{H}-benzo[b][1,4]benzodiazepine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | He, Y, Xia, R. | Deposit date: | 2023-07-01 | Release date: | 2024-03-20 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structural basis of ligand recognition and design of antihistamines targeting histamine H 4 receptor. Nat Commun, 15, 2024
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8JXW
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![BU of 8jxw by Molmil](/molmil-images/mine/8jxw) | VUF6884-bound H4R/Gi complex | Descriptor: | 2-chloranyl-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | He, Y, Xia, R. | Deposit date: | 2023-07-01 | Release date: | 2024-03-20 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural basis of ligand recognition and design of antihistamines targeting histamine H 4 receptor. Nat Commun, 15, 2024
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8JXX
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![BU of 8jxx by Molmil](/molmil-images/mine/8jxx) | Clobenpropit-bound H4R/Gi complex | Descriptor: | 3-(1~{H}-imidazol-4-yl)propyl ~{N}'-[(4-chlorophenyl)methyl]carbamimidothioate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | He, Y, Xia, R. | Deposit date: | 2023-07-01 | Release date: | 2024-03-20 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Structural basis of ligand recognition and design of antihistamines targeting histamine H 4 receptor. Nat Commun, 15, 2024
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6UH3
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![BU of 6uh3 by Molmil](/molmil-images/mine/6uh3) | Crystal structure of bacterial heliorhodopsin 48C12 | Descriptor: | DI(HYDROXYETHYL)ETHER, Heliorhodopsin, PALMITIC ACID, ... | Authors: | Lu, Y, Zhou, X.E, Gao, X, Xia, R, Xu, Z, Wang, N, Leng, Y, Melcher, K, Xu, H.E, He, Y. | Deposit date: | 2019-09-26 | Release date: | 2019-12-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of heliorhodopsin 48C12. Cell Res., 30, 2020
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3BU2
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![BU of 3bu2 by Molmil](/molmil-images/mine/3bu2) | Crystal structure of a tRNA-binding protein from Staphylococcus saprophyticus subsp. saprophyticus. Northeast Structural Genomics Consortium target SyR77 | Descriptor: | Putative tRNA-binding protein | Authors: | Seetharaman, J, Su, M, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-12-31 | Release date: | 2008-01-22 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a tRNA-binding protein from Staphylococcus saprophyticus subsp. saprophyticus. To be Published
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2R7F
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![BU of 2r7f by Molmil](/molmil-images/mine/2r7f) | Crystal structure of ribonuclease II family protein from Deinococcus radiodurans, hexagonal crystal form. NorthEast Structural Genomics target DrR63 | Descriptor: | Ribonuclease II family protein | Authors: | Seetharaman, J, Neely, H, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-09-07 | Release date: | 2007-10-02 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Structure and Enzymatic Properties of a Novel RNase II Family Enzyme from Deinococcus radiodurans. J.Mol.Biol., 415, 2012
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1T3H
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![BU of 1t3h by Molmil](/molmil-images/mine/1t3h) | X-ray Structure of Dephospho-CoA Kinase from E. coli Norteast Structural Genomics Consortium Target ER57 | Descriptor: | Dephospho-CoA kinase, SULFATE ION | Authors: | Kuzin, A.P, Chen, Y, Forouhar, F, Edstrom, W, Benach, J, Vorobiev, S, Acton, T, Shastry, R, Ma, L.-C, Xia, R, Montelione, G, Tong, L, Hunt, J, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-04-26 | Release date: | 2004-05-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray Structure of Dephospho-CoA Kinase from E. coli
Norteast Structural Genomics Consortium Target ER57 TO BE PUBLISHED
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1YDM
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![BU of 1ydm by Molmil](/molmil-images/mine/1ydm) | X-Ray structure of Northeast Structural Genomics target SR44 | Descriptor: | Hypothetical protein yqgN, SULFATE ION | Authors: | Kuzin, A.P, Jianwei, S, Vorobiev, S, Acton, T, Xia, R, Ma, L.-C, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-12-24 | Release date: | 2005-01-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-Ray structure of Northeast Structural Genomics target SR44 To be Published
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2R7D
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![BU of 2r7d by Molmil](/molmil-images/mine/2r7d) | Crystal structure of ribonuclease II family protein from Deinococcus radiodurans, triclinic crystal form. NorthEast Structural Genomics target DrR63 | Descriptor: | MAGNESIUM ION, Ribonuclease II family protein | Authors: | Seetharaman, J, Neely, H, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-09-07 | Release date: | 2007-10-02 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Structure and Enzymatic Properties of a Novel RNase II Family Enzyme from Deinococcus radiodurans. J.Mol.Biol., 415, 2012
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2PIH
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![BU of 2pih by Molmil](/molmil-images/mine/2pih) | Crystal structure of Protein ymcA from Bacillus subtilis, NorthEast Structural Genomics target SR375 | Descriptor: | Protein ymcA | Authors: | Seetharaman, J, Abashidze, M, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-04-13 | Release date: | 2007-05-01 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of Protein ymcA from Bacillus subtilis. To be Published
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2PIF
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![BU of 2pif by Molmil](/molmil-images/mine/2pif) | Crystal structure of UPF0317 protein PSPTO_5379 from Pseudomonas syringae pv. tomato. NorthEast Structural Genomics target PsR181 | Descriptor: | UPF0317 protein PSPTO_5379 | Authors: | Seetharaman, J, Abashidze, M, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-04-13 | Release date: | 2007-05-01 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of UPF0317 protein PSPTO_5379 from Pseudomonas syringae pv. tomato. To be Published
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2PSB
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![BU of 2psb by Molmil](/molmil-images/mine/2psb) | Crystal structure of YerB protein from Bacillus subtilis. NorthEast Structural Genomics target SR586 | Descriptor: | YerB protein | Authors: | Seetharaman, J, Chen, Y, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-05-04 | Release date: | 2007-05-15 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of YerB protein from Bacillus subtilis. To be Published
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2P3Y
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![BU of 2p3y by Molmil](/molmil-images/mine/2p3y) | Crystal structure of VPA0735 from Vibrio parahaemolyticus. NorthEast Structural Genomics target VpR109 | Descriptor: | Hypothetical protein VPA0735 | Authors: | Seetharaman, J, Neely, H, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-03-10 | Release date: | 2007-03-27 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of VPA0735 from Vibrio parahaemolyticus. To be Published
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2QGZ
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![BU of 2qgz by Molmil](/molmil-images/mine/2qgz) | Crystal structure of a putative primosome component from Streptococcus pyogenes serotype M3. Northeast Structural Genomics target DR58 | Descriptor: | PHOSPHATE ION, Putative primosome component | Authors: | Seetharaman, J, Chen, Y, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-06-29 | Release date: | 2007-07-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of a putative primosome component from Streptococcus pyogenes serotype M3. To be Published
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7DFL
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![BU of 7dfl by Molmil](/molmil-images/mine/7dfl) | Cryo-EM structure of histamine H1 receptor Gq complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | Authors: | He, Y, Xia, R, Wang, N, Xu, Z. | Deposit date: | 2020-11-09 | Release date: | 2021-03-31 | Last modified: | 2021-04-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of the human histamine H 1 receptor/G q complex. Nat Commun, 12, 2021
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3LRQ
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![BU of 3lrq by Molmil](/molmil-images/mine/3lrq) | Crystal structure of the U-box domain of human ubiquitin-protein ligase (E3), NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR4604D. | Descriptor: | E3 ubiquitin-protein ligase TRIM37, ZINC ION | Authors: | Kuzin, A, Chen, Y, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-02-11 | Release date: | 2010-03-23 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.292 Å) | Cite: | E3 UBIQUITIN-PROTEIN LIGASE RING DOMAIN FROM HUMAN TRIPARTITE MOTIF-CONTAINING PROTEIN 37 (TRIM37), NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR4604D. To be Published
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3CNW
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![BU of 3cnw by Molmil](/molmil-images/mine/3cnw) | Three-dimensional structure of the protein XoxI (Q81AY6) from Bacillus cereus. Northeast Structural Genomics Consortium target BcR196. | Descriptor: | Protein XoxI | Authors: | Kuzin, A.P, Abashidze, M, Seetharaman, J, Wang, H, Ciccosanti, C, Mao, L, Xiao, R, Nair, R, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-03-26 | Release date: | 2008-04-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Three-dimensional structure of the protein XoxI (Q81AY6) from Bacillus cereus. Northeast Structural Genomics Consortium target BcR196. To Be Published
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3CER
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![BU of 3cer by Molmil](/molmil-images/mine/3cer) | Crystal structure of the exopolyphosphatase-like protein Q8G5J2. Northeast Structural Genomics Consortium target BlR13 | Descriptor: | Possible exopolyphosphatase-like protein, SULFATE ION | Authors: | Kuzin, A.P, Su, M, Chen, Y, Neely, H, Seetharaman, J, Shastry, R, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-02-29 | Release date: | 2008-04-01 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the exopolyphosphatase-like protein Q8G5J2. Northeast Structural Genomics Consortium target BlR13. To be Published
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1WYZ
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![BU of 1wyz by Molmil](/molmil-images/mine/1wyz) | X-Ray structure of the putative methyltransferase from Bacteroides thetaiotaomicron VPI-5482 at the resolution 2.5 A. Norteast Structural Genomics Consortium target Btr28 | Descriptor: | putative S-adenosylmethionine-dependent methyltransferase | Authors: | Kuzin, A.P, Chen, Y, Forouhar, F, Vorobiev, S.M, Acton, T, Ma, L.-C, Xiao, R, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-02-21 | Release date: | 2005-03-08 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-Ray structure of the putative methyltransferase from Bacteroides thetaiotaomicron VPI-5482 at the resolution 2.5 A. Norteast Structural Genomics Consortium target Btr28 To be Published
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1XBF
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![BU of 1xbf by Molmil](/molmil-images/mine/1xbf) | X-RAY STRUCTURE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET CAR10 FROM C. ACETOBUTYLICUM | Descriptor: | Clostridium acetobutylicum Q97KL0, SULFATE ION | Authors: | Kuzin, A.P, Chen, Y, Vorobiev, S, Yong, W, Acton, T, Ho, C.-K, Conover, K, Cooper, B, Ciano, M, Xiao, R, Montelione, G, Tong, L, Hunt, J, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-08-30 | Release date: | 2004-09-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-RAY STRUCTURE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET CAR10 FROM C. ACETOBUTYLICUM To be published
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3LJX
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![BU of 3ljx by Molmil](/molmil-images/mine/3ljx) | Crystal Structure of MmoQ Response regulator (fragment 20-298) from Methylococcus capsulatus str. Bath, Northeast Structural Genomics Consortium Target McR175G | Descriptor: | CHLORIDE ION, MmoQ Response regulator | Authors: | Kuzin, A, Scott, L, Forouhar, F, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-01-26 | Release date: | 2010-02-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Northeast Structural Genomics Consortium Target McR175G To be published, 2009
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