8JXX

Clobenpropit-bound H4R/Gi complex

Summary for 8JXX

Entry DOI	10.2210/pdb8jxx/pdb
EMDB information	36716
Descriptor	Histamine H4 receptor, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
Functional Keywords	gpcr-g-protein complex, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	157351.59
Authors	He, Y.,Xia, R. (deposition date: 2023-07-01, release date: 2024-03-20, Last modification date: 2024-04-03)
Primary citation	Xia, R.,Shi, S.,Xu, Z.,Vischer, H.F.,Windhorst, A.D.,Qian, Y.,Duan, Y.,Liang, J.,Chen, K.,Zhang, A.,Guo, C.,Leurs, R.,He, Y. Structural basis of ligand recognition and design of antihistamines targeting histamine H 4 receptor. Nat Commun, 15:2493-2493, 2024 Cited by PubMed: 38509098 DOI: 10.1038/s41467-024-46840-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.06 Å)

Structure validation