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PDB: 149 件
3F6I
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Structure of the SeMet labeled F4 fibrial chaperone FaeE
分子名称: Chaperone protein faeE
著者Van Molle, I, Moonens, K, Buts, L, Garcia-Pino, A, Wyns, L, De Greve, H, Bouckaert, J.
登録日2008-11-06
公開日2009-05-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.788 Å)
主引用文献The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces
Acta Crystallogr.,Sect.D, 65, 2009
3F65
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The F4 fimbrial chaperone FaeE does not self-cap its interactive surfaces
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Chaperone protein faeE, PHOSPHATE ION
著者Van Molle, I, Moonens, K, Buts, L, Garcia-Pino, A, Wyns, L, De Greve, H, Bouckaert, J.
登録日2008-11-05
公開日2009-05-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces
Acta Crystallogr.,Sect.D, 65, 2009
1KXT
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Camelid VHH Domains in Complex with Porcine Pancreatic alpha-Amylase
分子名称: ALPHA-AMYLASE, PANCREATIC, CALCIUM ION, ...
著者Desmyter, A, Spinelli, S, Payan, F, Lauwereys, M, Wyns, L, Muyldermans, S, Cambillau, C.
登録日2002-02-01
公開日2002-06-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.
J.Biol.Chem., 277, 2002
1KXV
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Camelid VHH Domains in Complex with Porcine Pancreatic alpha-Amylase
分子名称: ALPHA-AMYLASE, PANCREATIC, CAMELID VHH DOMAIN CAB10
著者Desmyter, A, Spinelli, S, Payan, F, Lauwereys, M, Wyns, L, Muyldermans, S, Cambillau, C.
登録日2002-02-01
公開日2002-06-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.
J.Biol.Chem., 277, 2002
1JTT
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Degenerate interfaces in antigen-antibody complexes
分子名称: FORMIC ACID, Lysozyme, SODIUM ION, ...
著者Decanniere, K, Transue, T.R, Desmyter, A, Maes, D, Muyldermans, S, Wyns, L.
登録日2001-08-22
公開日2001-12-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Degenerate interfaces in antigen-antibody complexes.
J.Mol.Biol., 313, 2001
1JTO
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Degenerate interfaces in antigen-antibody complexes
分子名称: Lysozyme, Vh Single-Domain Antibody
著者Decanniere, K, Transue, T.R, Desmyter, A, Maes, D, Muyldermans, S, Wyns, L.
登録日2001-08-21
公開日2001-10-31
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Degenerate interfaces in antigen-antibody complexes.
J.Mol.Biol., 313, 2001
1TR7
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FimH adhesin receptor binding domain from uropathogenic E. coli
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, FimH protein, ...
著者Bouckaert, J, Berglund, J, Schembri, M, De Genst, E, Cools, L, Wuhrer, M, Hung, C.S, Pinkner, J, Slattegard, R, Zavialov, A, Choudhury, D, Langermann, S, Hultgren, S.J, Wyns, L, Klemm, P, Oscarson, S, Knight, S.D, De Greve, H.
登録日2004-06-21
公開日2005-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin
Mol.Microbiol., 55, 2005
1UWF
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1.7 A resolution structure of the receptor binding domain of the FimH adhesin from uropathogenic E. coli
分子名称: FIMH PROTEIN, GLYCEROL, butyl alpha-D-mannopyranoside
著者Bouckaert, J, Berglund, J, Genst, E.D, Cools, L, Hung, C.-S, Wuhrer, M, Zavialov, A, Langermann, S, Hultgren, S, Wyns, L, Oscarson, S, Knight, S.D, De Greve, H.
登録日2004-02-05
公開日2005-02-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Receptor Binding Studies Disclose a Novel Class of High-Affinity Inhibitors of the Escherichia Coli Fimh Adhesin.
Mol.Microbiol., 55, 2005
1VUB
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CCDB, A TOPOISOMERASE POISON FROM E. COLI
分子名称: CCDB, CHLORIDE ION
著者Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L.
登録日1998-04-17
公開日1998-07-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999
1BIR
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RIBONUCLEASE T1, PHE 100 TO ALA MUTANT COMPLEXED WITH 2' GMP
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1
著者Doumen, J, Gonciarz, M, Zegers, I, Loris, R, Wyns, L, Steyaert, J.
登録日1996-01-04
公開日1996-08-17
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1.
Protein Sci., 5, 1996
1CES
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CRYSTALS OF DEMETALLIZED CONCANAVALIN A SOAKED WITH ZINC HAVE A ZINC ION BOUND IN THE S1 SITE
分子名称: CONCANAVALIN A, ZINC ION
著者Bouckaert, J, Loris, R, Poortmans, F, Wyns, L.
登録日1996-02-15
公開日1997-02-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A.
J.Biol.Chem., 271, 1996
1BZQ
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COMPLEX OF A DROMEDARY SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A
分子名称: PHOSPHATE ION, PROTEIN (ANTIBODY CAB-RN05), PROTEIN (RNASE A)
著者Decanniere, K, Desmyter, A, Gahroudhi, M, Lauwereys, M, Muyldermans, S, Wyns, L.
登録日1998-11-03
公開日1998-11-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops.
Structure Fold.Des., 7, 1999
1ENR
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CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH ZINC AND CALCIUM HAVING A ZINC ION BOUND IN THE S1 SITE AND A CALCIUM ION BOUND IN THE S2 SITE
分子名称: CALCIUM ION, CONCANAVALIN A, ZINC ION
著者Bouckaert, J, Loris, R, Poortmans, F, Wyns, L.
登録日1996-03-20
公開日1996-08-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A.
J.Biol.Chem., 271, 1996
1ENS
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CRYSTALS OF DEMETALLIZED CONCANAVALIN A SOAKED WITH COBALT HAVING A COBALT ION BOUND IN THE S1 SITE
分子名称: COBALT (II) ION, CONCANAVALIN A
著者Bouckaert, J, Loris, R, Poortmans, F, Wyns, L.
登録日1996-03-20
公開日1996-08-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A.
J.Biol.Chem., 271, 1996
1ENQ
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CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH ZINC HAVING A ZINC ION BOUND IN THE S1 SITE
分子名称: CONCANAVALIN A, ZINC ION
著者Bouckaert, J, Loris, R, Poortmans, F, Wyns, L.
登録日1996-03-20
公開日1996-08-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A.
J.Biol.Chem., 271, 1996
1BJQ
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THE DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH ADENINE
分子名称: ADENINE, CALCIUM ION, LECTIN, ...
著者Hamelryck, T.W, Loris, R, Bouckaert, J, Dao-Thi, M.H, Wyns, L, Etzler, M.
登録日1998-06-26
公開日1998-12-30
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus.
J.Mol.Biol., 286, 1999
1ONA
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CO-CRYSTALS OF CONCANAVALIN A WITH METHYL-3,6-DI-O-(ALPHA-D-MANNOPYRANOSYL)-ALPHA-D-MANNOPYRANOSIDE
分子名称: CALCIUM ION, CONCANAVALIN A, MANGANESE (II) ION, ...
著者Bouckaert, J, Maes, D, Poortmans, F, Wyns, L, Loris, R.
登録日1996-07-07
公開日1997-09-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A structure of the complex between concanavalin A and methyl-3,6-di-O-(alpha-D-mannopyranosyl)-alpha-D-mannopyranoside reveals two binding modes.
J.Biol.Chem., 271, 1996
1QDC
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MAN(APLHA1-6)MAN(ALPHA1-O)METHYL CONCANAVALIN A COMPLEX
分子名称: CALCIUM ION, CHLORIDE ION, MANGANESE (II) ION, ...
著者Bouckaert, J, Loris, R, Wyns, L.
登録日1998-07-14
公開日1999-10-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structures of Man(alpha1-3)Man(alpha1-O)Me and Man(alpha1-6)Man(alpha1-O)Me in complex with concanavalin A.
J.Biol.Chem., 274, 1999
1QDO
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MAN(APLHA1-3)MAN(ALPHA1-O)METHYL CONCANAVALIN A COMPLEX
分子名称: CALCIUM ION, MANGANESE (II) ION, PROTEIN (CONCANAVALIN A), ...
著者Bouckaert, J, Loris, R, Wyns, L.
登録日1999-05-24
公開日1999-10-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structures of Man(alpha1-3)Man(alpha1-O)Me and Man(alpha1-6)Man(alpha1-O)Me in complex with concanavalin A.
J.Biol.Chem., 274, 1999
2GSP
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RIBONUCLEASE T1/2',3'-CGPS AND 3'-GMP, 2 DAYS
分子名称: CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, GUANOSINE-3'-MONOPHOSPHATE, ...
著者Zegers, I, Wyns, L.
登録日1997-12-02
公開日1998-08-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
2O7K
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S. aureus thioredoxin
分子名称: Thioredoxin
著者Roos, G, Garcia-Pino, A, Van Belle, K, Brosens, E, Wahni, K, Vandenbussche, G, Wyns, L, Loris, R, Messens, J.
登録日2006-12-11
公開日2007-07-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin
J.Mol.Biol., 368, 2007
2PQX
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E. coli RNase 1 (in vivo folded)
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Ribonuclease I
著者Messens, J, Loris, R, Wyns, L.
登録日2007-05-03
公開日2007-09-18
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Crystal structure of E. coli ribonuclease 1
To be Published
1XFP
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Crystal structure of the CDR2 germline reversion mutant of cAb-Lys3 in complex with hen egg white lysozyme
分子名称: FORMIC ACID, Lysozyme C, heavy chain antibody
著者De Genst, E, Handelberg, F, Van Meirhaeghe, A, Vynck, S, Loris, R, Wyns, L, Muyldermans, S.
登録日2004-09-15
公開日2004-09-28
最終更新日2013-02-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Chemical Basis for the Affinity Maturation of a Camel Single Domain Antibody
J.Biol.Chem., 279, 2004
1ZMY
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cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme
分子名称: Antibody cabbcII-10:lys3, Lysozyme C
著者Saerens, D, Pellis, M, Loris, R, Pardon, E, Dumoulin, M, Matagne, A, Wyns, L, Muyldermans, S, Conrath, K.
登録日2005-05-11
公開日2005-10-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies
J.Mol.Biol., 352, 2005
1YVS
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Trimeric domain swapped barnase
分子名称: BARNASE, SULFATE ION
著者Zegers, I, Wyns, L.
登録日1998-12-10
公開日1999-02-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Trimeric domain-swapped barnase.
Proc.Natl.Acad.Sci.USA, 96, 1999

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