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PDB: 471 件

3TYZ
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Crystal Structure of the Yersinia pestis Dihydropteroate synthetase with substrate transition state complex.
分子名称: 2-amino-6-methylidene-6,7-dihydropteridin-4(3H)-one, 4-AMINOBENZOIC ACID, 7,8-dihydropteroate synthase, ...
著者Wu, Y.
登録日2011-09-26
公開日2012-03-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Catalysis and sulfa drug resistance in dihydropteroate synthase.
Science, 335, 2012
3TZN
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Crystal Structure of the Yersinia pestis Dihydropteroate synthase.
分子名称: 7,8-dihydropteroate synthase
著者Wu, Y.
登録日2011-09-27
公開日2012-03-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.083 Å)
主引用文献Catalysis and sulfa drug resistance in dihydropteroate synthase.
Science, 335, 2012
2ZB4
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Crystal structure of human 15-ketoprostaglandin delta-13-reductase in complex with NADP and 15-keto-PGE2
分子名称: (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin reductase 2, ...
著者Wu, Y.H, Wang, A.H.J, Ko, T.P, Guo, R.T, Hu, S.M, Chuang, L.M.
登録日2007-10-16
公開日2008-09-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2.
Structure, 16, 2008
1XU4
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ATPASE IN COMPLEX WITH AMP-PNP, MAGNESIUM AND POTASSIUM CO-F
分子名称: DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Wu, Y, Qian, X, He, Y, Moya, I.A, Luo, Y.
登録日2004-10-25
公開日2004-11-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of an ATPase-active form of Rad51 homolog from Methanococcus voltae. Insights into potassium dependence
J.Biol.Chem., 280, 2005
2ZB7
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Crystal structure of human 15-ketoprostaglandin delta-13-reductase in complex with NADPH and nicotinamide
分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NICOTINAMIDE, Prostaglandin reductase 2
著者Wu, Y.H, Wang, A.H.J, Ko, T.P, Guo, R.T, Hu, S.M, Chuang, L.M.
登録日2007-10-16
公開日2008-09-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2.
Structure, 16, 2008
5D81
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Crystal Structure of Ketosteroid Isomerase from Pseudomonas putida (pKSI); D40N, Y57(Cl-Y)
分子名称: Delta(5)-3-ketosteroid isomerase, SULFATE ION
著者Wu, Y, Fried, S.D, Boxer, S.G.
登録日2015-08-15
公開日2015-12-02
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Dissecting Proton Delocalization in an Enzyme's Hydrogen Bond Network with Unnatural Amino Acids.
Biochemistry, 54, 2015
3N6N
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crystal structure of EV71 RdRp in complex with Br-UTP
分子名称: 5-bromouridine 5'-(tetrahydrogen triphosphate), NICKEL (II) ION, RNA-dependent RNA polymerase
著者Wu, Y, Lou, Z.Y, Miao, Y, Yu, Y, Rao, Z.H.
登録日2010-05-26
公開日2011-06-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.
Protein Cell, 1, 2010
3N6M
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Crystal structure of EV71 RdRp in complex with GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, NICKEL (II) ION, RNA-dependent RNA polymerase
著者Wu, Y, Lou, Z.Y, Miao, Y, Yu, Y, Rao, Z.H.
登録日2010-05-26
公開日2011-06-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.
Protein Cell, 1, 2010
3NAF
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Structure of the Intracellular Gating Ring from the Human High-conductance Ca2+ gated K+ Channel (BK Channel)
分子名称: Calcium-activated potassium channel subunit alpha-1,Calcium-activated potassium channel subunit alpha-1,Calcium-activated potassium channel subunit alpha-1
著者Wu, Y, Yang, Y, Ye, S, Jiang, Y.
登録日2010-06-01
公開日2010-06-30
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel.
Nature, 466, 2010
8HKH
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Crystal structure of the LC/A1-DARPin18 complex
分子名称: BoNT/A, Designed ankyrin repeat protein 18, ZINC ION
著者Wu, Y, Leka, O, Kammerer, R.
登録日2022-11-26
公開日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A DARPin Increases the Catalytic Activity of BoNT/A1
To Be Published
6A3N
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Crystal structure of the PDE9 catalytic domain in complex with inhibitor 2
分子名称: 1-cyclopentyl-6-({(2R)-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxopropan-2-yl}amino)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ...
著者Wu, Y.N, Zhou, Q, Chen, Y.P, Luo, H.B.
登録日2018-06-15
公開日2019-04-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of Potent, Selective, and Orally Bioavailable Inhibitors against Phosphodiesterase-9, a Novel Target for the Treatment of Vascular Dementia.
J. Med. Chem., 62, 2019
5D82
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Crystal Structure of Ketosteroid Isomerase from Pseudomonas putida (pKSI); D40N, Y16(Cl-Y)
分子名称: Delta(5)-3-ketosteroid isomerase
著者Wu, Y, Fried, S.D, Boxer, S.G.
登録日2015-08-15
公開日2015-12-02
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Dissecting Proton Delocalization in an Enzyme's Hydrogen Bond Network with Unnatural Amino Acids.
Biochemistry, 54, 2015
5D83
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Crystal Structure of Ketosteroid Isomerase from Pseudomonas putida (pKSI); D40N, Y32(Cl-Y)
分子名称: Delta(5)-3-ketosteroid isomerase
著者Wu, Y, Fried, S.D, Boxer, S.G.
登録日2015-08-15
公開日2015-12-02
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Dissecting Proton Delocalization in an Enzyme's Hydrogen Bond Network with Unnatural Amino Acids.
Biochemistry, 54, 2015
1PG9
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NMR Solution Structure of an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link in a DNA Dodecamer Duplex
分子名称: 5'-D(*CP*CP*TP*CP*AP*GP*GP*CP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*GP*CP*CP*TP*GP*AP*GP*G)-3', CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II)
著者Wu, Y, Pradhan, P, Havener, J, Chaney, S.G, Campbel, S.L.
登録日2003-05-28
公開日2004-07-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR solution structure of an oxaliplatin 1,2-d(GG) intrastrand cross-link in a DNA dodecamer duplex
J.Mol.Biol., 341, 2004
1PGC
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BU of 1pgc by Molmil
NMR Solution Structure of an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link in a DNA Dodecamer Duplex
分子名称: 5'-D(*CP*CP*TP*CP*AP*GP*GP*CP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*GP*CP*CP*TP*GP*AP*GP*G)-3', CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II)
著者Wu, Y, Pradhan, P, Havener, J, Chaney, S.G, Campbel, S.L.
登録日2003-05-28
公開日2004-07-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR solution structure of an oxaliplatin 1,2-d(GG) intrastrand cross-link in a DNA dodecamer duplex
J.Mol.Biol., 341, 2004
3N6L
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BU of 3n6l by Molmil
The crystal structure of RNA-dependent RNA polymerase of EV71 virus
分子名称: NICKEL (II) ION, RNA-dependent RNA polymerase
著者Wu, Y, Rao, Z.H.
登録日2010-05-26
公開日2011-06-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.
Protein Cell, 1, 2010
7WOI
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BU of 7woi by Molmil
Structure of the shaft pilin Spa2 from Corynebacterium glutamicum
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Spa2
著者Wu, Y.F, Wang, L.T, Huang, Y.Y, Zhong, C, Zhou, J.
登録日2022-01-21
公開日2023-01-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Accelerating the design of pili-enabled living materials using an integrative technological workflow.
Nat.Chem.Biol., 2023
5Y10
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BU of 5y10 by Molmil
SFTSV Gn head domain
分子名称: Membrane glycoprotein polyprotein, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Wu, Y, Gao, F, Qi, J.X, Chai, Y, Gao, G.F.
登録日2017-07-19
公開日2017-09-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5Y0Y
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RVFV GN-AU
分子名称: GOLD ION, NSmGnGc
著者Wu, Y, Gao, F, Qi, J.X, Chai, Y, Gao, G.F.
登録日2017-07-19
公開日2017-09-13
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (3.398 Å)
主引用文献Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5Y11
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SFTSV GN with neutralizing antibody MAb4-5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAb 4-5 heavy chain, MAb 4-5 light chain, ...
著者Wu, Y, Gao, F, Qi, J.X, Chai, Y, Gao, G.F.
登録日2017-07-19
公開日2017-09-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5Y0W
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The structure of RVFV Gn head domain
分子名称: NSmGnGc
著者Wu, Y, Gao, F, Qi, J.X, Chai, Y, Gao, G.F.
登録日2017-07-19
公開日2017-09-13
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7XCD
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Crystal Structure of the Disease-Specific Protein of Rice Stripe Virus
分子名称: Disease specific protein
著者Wu, Y.K, Chen, L.F, Chen, P.
登録日2022-03-24
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Crystal Structure of the Disease-Specific Protein of Rice Stripe Virus
To Be Published
7XCC
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Crystal Structure of the Disease-Specific Protein of Rice Stripe Virus
分子名称: Disease specific protein
著者Wu, Y.K, Chen, L.F.
登録日2022-03-24
公開日2023-04-26
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of the Disease-Specific Protein of Rice Stripe Virus
To Be Published
1XAO
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Hsp40-Ydj1 dimerization domain
分子名称: Mitochondrial protein import protein MAS5
著者Wu, Y, Sha, B.
登録日2004-08-26
公開日2005-05-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The crystal structure of the C-terminal fragment of yeast Hsp40 Ydj1 reveals novel dimerization motif for Hsp40
J.Mol.Biol., 346, 2005
7V51
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BVMO_negative mutant D432V
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Putative flavin-binding monooxygenase
著者Wu, Y, Yu, H.-L.
登録日2021-08-16
公開日2023-02-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Precise regulation of the substrate selectivity of Baeyer-Villiger monooxygenase to minimize overoxidation of prazole sulfoxides.
CHINESE J CATAL, 51, 2023

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件を2024-06-05に公開中

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