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PDB: 26 results

9J5H
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BU of 9j5h by Molmil
Solution structure of disulfide-directed multicyclic peptides with affinity to pdl1
Descriptor: p1
Authors:Fan, S.H, Wu, C.L.
Deposit date:2024-08-12
Release date:2025-02-19
Last modified:2025-02-26
Method:SOLUTION NMR
Cite:Disulfide-Directed Multicyclic Peptides with N-Terminally Extendable alpha-Helices for Recognition and Activation of G Protein-Coupled Receptors.
J.Am.Chem.Soc., 147, 2025
9J5F
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BU of 9j5f by Molmil
Solution structure of disulfide-directed multicyclic peptides with n-terminal helix
Descriptor: m1-2
Authors:Fan, S.H, Wu, C.L.
Deposit date:2024-08-12
Release date:2025-02-19
Last modified:2025-02-26
Method:SOLUTION NMR
Cite:Disulfide-Directed Multicyclic Peptides with N-Terminally Extendable alpha-Helices for Recognition and Activation of G Protein-Coupled Receptors.
J.Am.Chem.Soc., 147, 2025
8YLR
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BU of 8ylr by Molmil
State 6 (S6) of yeast 80S ribosome bound to 2 tRNAs and eEF2 and eEF3 during tranlocation
Descriptor: 18S rRNA, 25S rRNA, 5.8S rRNA, ...
Authors:Cheng, J, Wu, C.L, Li, J.X, Zhang, X.Z.
Deposit date:2024-03-06
Release date:2024-12-11
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Snapshots of ribosome dynamics near atomic resolution in situ: a full insight into eukaryotic elongation cycle
To Be Published
8YLD
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BU of 8yld by Molmil
State 4a (S4a) of yeast 80S ribosome bound to 2 tRNAs and open eEF3 and eEF2 during translocation
Descriptor: 18S rRNA, 25S rRNA, 5.8S rRNA, ...
Authors:Cheng, J, Wu, C.L, Li, J.X, Zhang, X.Z.
Deposit date:2024-03-06
Release date:2024-12-11
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Snapshots of ribosome dynamics near atomic resolution in situ: a full insight into eukaryotic elongation cycle
To Be Published
8Z71
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BU of 8z71 by Molmil
State 1a (S1a) of yeast 80S ribosome bound to open eEF3 and 2 tRNAs and eEF1A during mRNA decoding
Descriptor: 18S rRNA, 25S rRNA, 5.8S rRNA, ...
Authors:Cheng, J, Wu, C.L, Li, J.X, Zhang, X.Z.
Deposit date:2024-04-19
Release date:2024-12-11
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Snapshots of ribosome dynamics near atomic resolution in situ: a full insight into eukaryotic elongation cycle
To Be Published
8Z70
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BU of 8z70 by Molmil
State 1 (S1) of yeast 80S ribosome bound to 2 tRNAs during mRNA decoding
Descriptor: 18S rRNA, 25S rRNA, 5.8S rRNA, ...
Authors:Cheng, J, Wu, C.L, Li, J.X, Zhang, X.Z.
Deposit date:2024-04-19
Release date:2024-12-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Snapshots of ribosome dynamics near atomic resolution in situ: a full insight into eukaryotic elongation cycle
To Be Published
7Y99
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BU of 7y99 by Molmil
Crystal Structure Analysis of cp2 bound BCLxl
Descriptor: Bcl-2-like protein 1, CP2 peptide, N-(2-acetamidoethyl)-4-(4,5-dihydro-1,3-thiazol-2-yl)benzamide
Authors:Li, F.W, Liu, C, Wu, C.L, Wu, D.L.
Deposit date:2022-06-24
Release date:2023-09-27
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy.
Nat Commun, 15, 2024
7YAA
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BU of 7yaa by Molmil
Crystal structure analysis of cp3 bound BCLxl
Descriptor: Bcl-2-like protein 1, GLYCEROL, N-(2-acetamidoethyl)-4-(4-methanoyl-1,3-thiazol-2-yl)benzamide, ...
Authors:Li, F.W, Liu, C, Wu, C.L, Wu, D.L.
Deposit date:2022-06-27
Release date:2023-11-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy.
Nat Commun, 15, 2024
7Y8D
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BU of 7y8d by Molmil
Crystal structure of cp1 bound BCLxl
Descriptor: (2R)-3-[2-(aminomethyl)-3-azanyl-1-[4-[2-(2-chloranylethanoylamino)ethylcarbamoyl]phenyl]prop-1-enyl]sulfanyl-2-(carboxyamino)propanoic acid, Bcl-2-like protein 1, cp1 peptide
Authors:Li, F.W, Liu, C, Wu, C.L, Wu, D.L.
Deposit date:2022-06-23
Release date:2023-11-15
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy.
Nat Commun, 15, 2024
7YA5
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BU of 7ya5 by Molmil
Crystal structure analysis of cp1 bound BCL2/G101V
Descriptor: (2R)-3-[2-(aminomethyl)-3-azanyl-1-[4-[2-(2-chloranylethanoylamino)ethylcarbamoyl]phenyl]prop-1-enyl]sulfanyl-2-(carboxyamino)propanoic acid, Apoptosis regulator Bcl-2, cp1 peptide
Authors:Li, F.W, Liu, C, Wu, C.L, Wu, D.L.
Deposit date:2022-06-27
Release date:2023-11-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy.
Nat Commun, 15, 2024
7YRV
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BU of 7yrv by Molmil
Solution structures of a disulfide-directed multicyclic peptide with affinity for FGFR1
Descriptor: LF1
Authors:Fan, S.H, Wu, C.L.
Deposit date:2022-08-10
Release date:2023-08-16
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Peptide Ligands and Drugs.
J.Am.Chem.Soc., 145, 2023
7YRW
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BU of 7yrw by Molmil
Solution structures of a disulfide-directed multicyclic peptide with affinity for HER2
Descriptor: LH2
Authors:Fan, S.H, Wu, C.L.
Deposit date:2022-08-10
Release date:2023-08-16
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Peptide Ligands and Drugs.
J.Am.Chem.Soc., 145, 2023
7YRX
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BU of 7yrx by Molmil
Solution structures of a disulfide-directed multicyclic peptide with affinity for HER3
Descriptor: LH3
Authors:Fan, S.H, Wu, C.L.
Deposit date:2022-08-11
Release date:2023-08-16
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Peptide Ligands and Drugs.
J.Am.Chem.Soc., 145, 2023
8GUC
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BU of 8guc by Molmil
Solution structures of a disulfide-rich peptide selected via Cellular Protein Quality Control
Descriptor: xm63
Authors:Fan, S.H, Wu, C.L.
Deposit date:2022-09-11
Release date:2023-09-13
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:selection and evolution of Disulfide-rich peptides via cellular protein quality control
To Be Published
7W8K
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BU of 7w8k by Molmil
Solution structures of a disulfide-rich peptide that can bind mdm2
Descriptor: drp1
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-08
Release date:2022-06-08
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8R
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BU of 7w8r by Molmil
Solution structures of a disulfide-rich peptide that can bind mdm2
Descriptor: drp2-b
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-08
Release date:2022-06-08
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8O
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BU of 7w8o by Molmil
Solution structures of a disulfide-rich peptide that can bind mdm2
Descriptor: drp2-a
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-08
Release date:2022-06-08
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W96
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BU of 7w96 by Molmil
Solution structures of a disulfide-rich peptide that can bind KEAP1
Descriptor: drp6
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-09
Release date:2022-11-09
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7WE3
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BU of 7we3 by Molmil
Solution structures of a disulfide-rich peptide that can bind CD28
Descriptor: DRP8II
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-22
Release date:2022-11-09
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7WEI
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BU of 7wei by Molmil
Solution structures of a disulfide-rich peptide that can bind CD28
Descriptor: drp8I
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-23
Release date:2022-11-09
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8Z
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BU of 7w8z by Molmil
Solution structures of a disulfide-rich peptide designed through sequence grafting
Descriptor: drp4
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-09
Release date:2022-06-08
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
7W8T
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BU of 7w8t by Molmil
Solution structures of a disulfide-rich peptide that can bind KEAP1
Descriptor: DRP3
Authors:Fan, S.H, Wu, Y.P, Wu, C.L.
Deposit date:2021-12-08
Release date:2022-06-08
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery.
Chem Sci, 13, 2022
8WW1
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BU of 8ww1 by Molmil
Cyclic peptide with affinity for HER3
Descriptor: HER3-1
Authors:Fan, S.H, Wu, C.L.
Deposit date:2023-10-24
Release date:2024-10-30
Method:SOLUTION NMR
Cite:Combinations of Disulfide-Directing Motifs in Tandem Enabling the De-sign and Discovery of Multicyclic Peptide Binders
To Be Published
8WVS
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BU of 8wvs by Molmil
The structure of CPPCXC motif
Descriptor: SER-CYS-PRO-PRO-CYS-LYS-CYS-GLY-TRP
Authors:Fan, S.H, Wu, C.L.
Deposit date:2023-10-24
Release date:2024-10-30
Method:SOLUTION NMR
Cite:Combinations of Disulfide-Directing Motifs in Tandem Enabling the De-sign and Discovery of Multicyclic Peptide Binders
To Be Published
8WW0
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BU of 8ww0 by Molmil
Cyclic peptide with affinity for ICOS
Descriptor: icos-1
Authors:Fan, S.H, Wu, C.L.
Deposit date:2023-10-24
Release date:2024-10-30
Method:SOLUTION NMR
Cite:Combinations of Disulfide-Directing Motifs in Tandem Enabling the De-sign and Discovery of Multicyclic Peptide Binders
To Be Published

 

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PDB entries from 2025-06-11

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