5GWK
 
 | | Human topoisomerase IIalpha in complex with DNA and etoposide | | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ... | | 著者 | Wang, Y.R, Wu, C.C, Chan, N.L. | | 登録日 | 2016-09-12 | | 公開日 | 2017-08-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.152 Å) | | 主引用文献 | Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res., 45, 2017
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4M27
 | | Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-Arg | | 分子名称: | ARGININE, FE (III) ION, L-arginine beta-hydroxylase, ... | | 著者 | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | | 登録日 | 2013-08-05 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
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4M2K
 | | Crystal structure of PLP-dependent cyclase OrfR in complex with PLP | | 分子名称: | Aminotransferase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | | 登録日 | 2013-08-05 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
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4NE0
 | | Crystal structure of non-heme iron oxygenase OrfP D157A mutant in complex with (3S)-hydroxy-L-Arg | | 分子名称: | (2S,3S)-3-HYDROXYARGININE, FE (III) ION, L-arginine beta-hydroxylase, ... | | 著者 | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | | 登録日 | 2013-10-28 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms
Angew.Chem.Int.Ed.Engl., 53, 2014
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8HCG
 | | Crystal structure of mTREX1-dAMP complex | | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids.
Nucleic Acids Res., 51, 2023
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8HCE
 | | Crystal structure of mTREX1-CMP complex | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMMONIUM ION, CYTIDINE-5'-MONOPHOSPHATE, ... | | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids.
Nucleic Acids Res., 51, 2023
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8HCF
 | | Crystal structure of mTREX1-UMP complex | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, Three-prime repair exonuclease 1, ... | | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | | 登録日 | 2022-11-01 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids.
Nucleic Acids Res., 51, 2023
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5GWJ
 | | Structure of a Human topoisomerase IIbeta fragment in complex with DNA and E7873S | | 分子名称: | DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ... | | 著者 | Wang, Y.R, Chen, S.F, Wu, C.C, Chan, N.L. | | 登録日 | 2016-09-12 | | 公開日 | 2017-08-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.566 Å) | | 主引用文献 | Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res., 45, 2017
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4M2I
 | | Crystal structure of non-heme iron oxygenase OrfP in complex with Fe | | 分子名称: | FE (III) ION, L-arginine beta-hydroxylase | | 著者 | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | | 登録日 | 2013-08-05 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
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4M26
 | | Crystal structure of non-heme iron oxygenase OrfP in complex with Fe, succinate, and (3S)-hydroxy-L-Arg | | 分子名称: | (2S,3S)-3-HYDROXYARGININE, 2-OXOGLUTARIC ACID, FE (III) ION, ... | | 著者 | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | | 登録日 | 2013-08-05 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
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4M2F
 | | Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-canavanine | | 分子名称: | FE (III) ION, L-CANAVANINE, L-arginine beta-hydroxylase | | 著者 | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | | 登録日 | 2013-08-05 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
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4M23
 | | Crystal structure of non-heme iron oxygenase OrfP | | 分子名称: | L-arginine beta-hydroxylase | | 著者 | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | | 登録日 | 2013-08-05 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
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4M2M
 | | Crystal structure of PLP-dependent cyclase OrfR in complex with PLP-L-Arg | | 分子名称: | ARGININE, Aminotransferase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | | 登録日 | 2013-08-05 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
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7CIX
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4M2G
 | | Crystal structure of non-heme iron oxygenase OrfP in complex with Fe, succinate, and (3R,4R)-dihydroxy-L-Arg | | 分子名称: | FE (III) ION, L-arginine beta-hydroxylase, SUCCINIC ACID, ... | | 著者 | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | | 登録日 | 2013-08-05 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
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4M25
 | | Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and alpha-ketoglutaric acid | | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, L-arginine beta-hydroxylase | | 著者 | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | | 登録日 | 2013-08-05 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
Angew.Chem.Int.Ed.Engl., 53, 2014
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5GIF
 | | Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Binary Complex with Acetyl-CoA | | 分子名称: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, ACETYL COENZYME *A, Dopamine N-acetyltransferase | | 著者 | Yang, Y.C, Wu, C.Y, Cheng, H.C, Lyu, P.C. | | 登録日 | 2016-06-23 | | 公開日 | 2017-07-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Binary Complex with Acetyl-CoA
To Be Published
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5CHL
 | | Structural basis of H2A.Z recognition by YL1 histone chaperone component of SRCAP/SWR1 chromatin remodeling complex | | 分子名称: | Histone H2A.Z, Vacuolar protein sorting-associated protein 72 homolog | | 著者 | Shan, S, Liang, X, Pan, L, Wu, C, Zhou, Z. | | 登録日 | 2015-07-10 | | 公開日 | 2016-03-09 | | 最終更新日 | 2017-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.892 Å) | | 主引用文献 | Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1
Nat.Struct.Mol.Biol., 23, 2016
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1SFU
 | | Crystal structure of the viral Zalpha domain bound to left-handed Z-DNA | | 分子名称: | 34L protein, 5'-D(*T*CP*GP*CP*GP*CP*G)-3' | | 著者 | Ha, S.C, Van Quyen, D, Wu, C.A, Lowenhaupt, K, Rich, A, Kim, Y.G, Kim, K.K. | | 登録日 | 2004-02-20 | | 公開日 | 2004-08-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A poxvirus protein forms a complex with left-handed Z-DNA: crystal structure of a Yatapoxvirus Zalpha bound to DNA.
Proc.Natl.Acad.Sci.USA, 101, 2004
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5GIG
 | | Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-dopamine | | 分子名称: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, COENZYME A, Dopamine N-acetyltransferase, ... | | 著者 | Yang, Y.C, Wu, C.Y, Cheng, H.C, Lyu, P.C. | | 登録日 | 2016-06-23 | | 公開日 | 2017-07-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-dopamine
To Be Published
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5GII
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7CE2
 | | The Crystal structure of TeNT Hc complexed with neutralizing antibody | | 分子名称: | Tetanus toxin, neutralizing antibody heavy chain, neutralizing antibody light chain | | 著者 | Wang, X, Wang, Y, Wu, C, Yu, J, Liao, H. | | 登録日 | 2020-06-21 | | 公開日 | 2021-04-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural basis of tetanus toxin neutralization by native human monoclonal antibodies.
Cell Rep, 35, 2021
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5GIH
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4ZO3
 | | AidC, a Dizinc Quorum-Quenching Lactonase, in complex with a product N-hexnoyl-L-homoserine | | 分子名称: | Acylhomoserine lactonase, N-hexanoyl-L-homoserine, ZINC ION | | 著者 | Mascarenhas, R, Thomas, P.W, Wu, C.-X, Nocek, B.P, Hoang, Q, Fast, W, Liu, D. | | 登録日 | 2015-05-05 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Structural and Biochemical Characterization of AidC, a Quorum-Quenching Lactonase with Atypical Selectivity.
Biochemistry, 54, 2015
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1NYP
 | | 4th LIM domain of PINCH protein | | 分子名称: | PINCH protein, ZINC ION | | 著者 | Velyvis, A, Vaynberg, J, Vinogradova, O, Zhang, Y, Wu, C, Qin, J. | | 登録日 | 2003-02-13 | | 公開日 | 2003-07-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and functional insights into PINCH LIM4 domain-mediated integrin signaling
Nat.Struct.Biol., 10, 2003
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