8K8E
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![BU of 8k8e by Molmil](/molmil-images/mine/8k8e) | Human gamma-secretase in complex with a substrate mimetic | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Shi, Y.G, Zhou, R, Wolfe, M.S. | Deposit date: | 2023-07-29 | Release date: | 2024-01-31 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Familial Alzheimer mutations stabilize synaptotoxic gamma-secretase-substrate complexes. Cell Rep, 43, 2024
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2KGP
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![BU of 2kgp by Molmil](/molmil-images/mine/2kgp) | Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by Novantrone (Mitoxantrone) | Descriptor: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, RNA (25-MER) | Authors: | Zheng, S, Chen, Y, Donahue, C.P, Wolfe, M.S, Varani, G. | Deposit date: | 2009-03-13 | Release date: | 2009-06-02 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone). Chem.Biol., 16, 2009
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