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PDB: 358 件
3INS
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STRUCTURE OF INSULIN. RESULTS OF JOINT NEUTRON AND X-RAY REFINEMENT
分子名称: INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION
著者Wlodawer, A, Savage, H.
登録日1988-10-14
公開日1989-01-09
最終更新日2017-11-29
実験手法NEUTRON DIFFRACTION (1.5 Å), X-RAY DIFFRACTION
主引用文献Structure of insulin: results of joint neutron and X-ray refinement.
Acta Crystallogr.,Sect.B, 45, 1989
1FMB
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EIAV PROTEASE COMPLEXED WITH THE INHIBITOR HBY-793
分子名称: EIAV PROTEASE, [2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL
著者Wlodawer, A, Gustchina, A, Zdanov, A, Kervinen, J.
登録日1996-02-27
公開日1996-10-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of equine infectious anemia virus proteinase complexed with an inhibitor.
Protein Sci., 5, 1996
1FIV
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STRUCTURE OF AN INHIBITOR COMPLEX OF PROTEINASE FROM FELINE IMMUNODEFICIENCY VIRUS
分子名称: FIV PROTEASE, FIV PROTEASE INHIBITOR ACE-ALN-VAL-STA-GLU-ALN-NH2
著者Wlodawer, A, Gustchina, A, Reshetnikova, L, Lubkowski, J, Zdanov, A.
登録日1995-05-04
公開日1995-07-31
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of an inhibitor complex of the proteinase from feline immunodeficiency virus.
Nat.Struct.Biol., 2, 1995
3HIK
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Structure of human Plk1-PBD in complex with PLHSpT
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Pentamer phosphopeptide, ...
著者Wlodawer, A, Moulaei, T.
登録日2009-05-20
公開日2009-06-09
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
Nat.Struct.Mol.Biol., 16, 2009
1RCB
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CRYSTAL STRUCTURE OF HUMAN RECOMBINANT INTERLEUKIN-4 AT 2.25 ANGSTROMS RESOLUTION
分子名称: INTERLEUKIN-4
著者Wlodawer, A, Pavlovsky, A, Gustchina, A.
登録日1992-08-26
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of human recombinant interleukin-4 at 2.25 A resolution.
FEBS Lett., 309, 1992
1SN7
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KUMAMOLISIN-AS, APOENZYME
分子名称: CALCIUM ION, kumamolisin-As
著者Wlodawer, A, Li, M, Gustchina, A, Oda, K, Nishino, T.
登録日2004-03-10
公開日2004-06-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic and biochemical investigations of kumamolisin-as, a serine-carboxyl peptidase with collagenase activity.
J.Biol.Chem., 279, 2004
1ZTH
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Crystal Structure of A.fulgidus Rio1 serine protein kinase bound to ADP and Manganese ion
分子名称: ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, Rio1 serine protein kinase
著者Wlodawer, A, LaRonde-LeBlanc, N.
登録日2005-05-27
公開日2005-07-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structure and activity of the atypical serine kinase Rio1.
Febs J., 272, 2005
1ZTF
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Crystal Structure of A.fulgidus Rio1 serine protein kinase
分子名称: 2-(6-AMINO-OCTAHYDRO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, Rio1 serine protein kinase
著者Wlodawer, A, LaRonde-LeBlanc, N.
登録日2005-05-26
公開日2005-07-19
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structure and activity of the atypical serine kinase Rio1.
Febs J., 272, 2005
8HVP
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STRUCTURE AT 2.5-ANGSTROMS RESOLUTION OF CHEMICALLY SYNTHESIZED HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE COMPLEXED WITH A HYDROXYETHYLENE*-BASED INHIBITOR
分子名称: HIV-1 PROTEASE, INHIBITOR VAL-SER-GLN-ASN-LEU-PSI(CH(OH)-CH2)-VAL-ILE-VAL (U-85548E)
著者Jaskolski, M, Miller, M, Tomasselli, A.G, Sawyer, T.K, Staples, D.G, Heinrikson, R.L, Schneider, J, Kent, S.B.H, Wlodawer, A.
登録日1990-10-26
公開日1993-10-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure at 2.5-A resolution of chemically synthesized human immunodeficiency virus type 1 protease complexed with a hydroxyethylene-based inhibitor.
Biochemistry, 30, 1991
4RLD
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Crystal structure of kkf mutant of bla G 2 protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aspartic protease Bla g 2, ZINC ION
著者Li, M, Gustchina, A, Pomes, A, Wlodawer, A.
登録日2014-10-16
公開日2015-10-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献to be determined
To be Published
8RSA
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CRYSTAL STRUCTURE OF TWO COVALENT NUCLEOSIDE DERIVATIVES OF RIBONUCLEASE A
分子名称: 3'-DEOXY-3'-ACETAMIDO-THYMIDINE, RIBONUCLEASE A
著者Nachman, J, Wlodawer, A.
登録日1989-08-28
公開日1991-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of two covalent nucleoside derivatives of ribonuclease A.
Biochemistry, 29, 1990
1CXU
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1.42A RESOLUTION ASV INTEGRASE CORE DOMAIN FROM CITRATE
分子名称: CITRIC ACID, GLYCEROL, PROTEIN (AVIAN SARCOMA VIRUS INTEGRASE)
著者Lubkowski, J, Dauter, Z, Yang, F, Alexandratos, J, Wlodawer, A.
登録日1999-08-30
公開日1999-09-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant.
Biochemistry, 38, 1999
5L04
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STRUCTURE OF INTERFERON LAMBDA 1 RECEPTOR WITH HUMAN KINASE JAK1
分子名称: Interferon lambda receptor 1, Tyrosine-protein kinase JAK1
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2016-07-26
公開日2016-10-12
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of a Complex of the Intracellular Domain of Interferon lambda Receptor 1 (IFNLR1) and the FERM/SH2 Domains of Human JAK1.
J. Mol. Biol., 428, 2016
8PTI
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CRYSTAL STRUCTURE OF A Y35G MUTANT OF BOVINE PANCREATIC TRYPSIN INHIBITOR
分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR
著者Housset, D, Kim, K.-S, Fuchs, J, Woodward, C, Wlodawer, A.
登録日1990-12-17
公開日1991-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a Y35G mutant of bovine pancreatic trypsin inhibitor.
J.Mol.Biol., 220, 1991
6FIV
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STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITH AN EFFICIENT INHIBITOR OF FIV PR
分子名称: RETROPEPSIN, SULFATE ION, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate
著者Li, M, Lee, T, Morris, G, Laco, G, Wong, C, Olson, A, Elder, J, Wlodawer, A, Gustchina, A.
登録日1998-12-02
公開日1998-12-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease
Proteins, 38, 2000
8DVH
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Crystal structure of ATP-dependent Lon protease from Bacillus subtillis (BsLonBA)
分子名称: Lon protease 2, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, SODIUM ION
著者Sekula, B, Li, M, Gustchina, A, Wlodawer, A.
登録日2022-07-29
公開日2022-11-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Unique Structural Fold of LonBA Protease from Bacillus subtilis, a Member of a Newly Identified Subfamily of Lon Proteases.
Int J Mol Sci, 23, 2022
1CMS
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THE THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT BOVINE CHYMOSIN AT 2.3 ANGSTROMS RESOLUTION
分子名称: PROCHYMOSIN A/B PRECURSOR
著者Gilliland, G.L, Winborne, E.L, Nachman, J, Wlodawer, A.
登録日1989-10-12
公開日1990-01-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The three-dimensional structure of recombinant bovine chymosin at 2.3 A resolution.
Proteins, 8, 1990
1CXQ
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ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN FROM AMMONIUM SULFATE
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AVIAN SARCOMA VIRUS INTEGRASE, GLYCEROL
著者Lubkowski, J, Dauter, Z, Yang, F, Alexandratos, J, Merkel, G, Skalka, A.M, Wlodawer, A.
登録日1999-08-30
公開日1999-09-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.02 Å)
主引用文献Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant.
Biochemistry, 38, 1999
1CZB
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ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN FROM HEPES
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AVIAN SARCOMA VIRUS INTEGRASE
著者Lubkowski, J, Dauter, Z, Yang, F, Alexandratos, J, Merkel, G, Skalka, A.M, Wlodawer, A.
登録日1999-09-01
公開日1999-09-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant.
Biochemistry, 38, 1999
1CZ9
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ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN (D64N) FROM CITRATE
分子名称: AVIAN SARCOMA VIRUS INTEGRASE, CITRIC ACID, SULFATE ION
著者Lubkowski, J, Dauter, Z, Yang, F, Alexandratos, J, Merkel, G, Skalka, A.M, Wlodawer, A.
登録日1999-09-01
公開日1999-09-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant.
Biochemistry, 38, 1999
6EX7
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Crystal structure of NDM-1 metallo-beta-lactamase in complex with Cd ions and a hydrolyzed beta-lactam ligand - new refinement
分子名称: 1,2-ETHANEDIOL, 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, CADMIUM ION, ...
著者Kim, Y, Raczynska, J.E, Shabalin, I.G, Jaskolski, M, Minor, W, Wlodawer, A, Tesar, C, Jedrzejczak, R, Babnigg, J, Mire, J, Sacchettini, J, Joachimiak, A.
登録日2017-11-07
公開日2017-12-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A close look onto structural models and primary ligands of metallo-beta-lactamases.
Drug Resist. Updat., 40, 2018
7UT3
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Crystal structure of complex of Fab, G10C with GalNAc-pNP
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-nitrophenyl 2-acetamido-2-deoxy-alpha-D-galactopyranoside, Fab protein heavy chain, ...
著者Li, M, Wlodawer, A.
登録日2022-04-26
公開日2022-09-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Development of a GalNAc-Tyrosine-Specific Monoclonal Antibody and Detection of Tyrosine O -GalNAcylation in Numerous Human Tissues and Cell Lines.
J.Am.Chem.Soc., 144, 2022
7UPZ
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Structural basis for cell type specific DNA binding of C/EBPbeta: the case of cell cycle inhibitor p15INK4b promoter
分子名称: CCAAT/enhancer-binding protein beta, DNA (5'-D(*AP*TP*TP*CP*TP*TP*AP*AP*GP*AP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*TP*CP*TP*TP*TP*CP*TP*TP*AP*AP*GP*AP*A)-3')
著者Lountos, G.T, Cherry, S, Tropea, J.E, Wlodawer, A, Miller, M.
登録日2022-04-18
公開日2022-11-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.487 Å)
主引用文献Structural basis for cell type specific DNA binding of C/EBP beta : The case of cell cycle inhibitor p15INK4b promoter.
J.Struct.Biol., 214, 2022
5FIV
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STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITH AN EFFICIENT INHIBITOR OF FIV PR
分子名称: RETROPEPSIN, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate
著者Li, M, Lee, T, Morris, G, Laco, G, Wong, C, Olson, A, Elder, J, Wlodawer, A, Gustchina, A.
登録日1998-12-02
公開日1998-12-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease
Proteins, 38, 2000
9RSA
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CRYSTAL STRUCTURE OF TWO COVALENT NUCLEOSIDE DERIVATIVES OF RIBONUCLEASE A
分子名称: 3'-DEOXY-3'-ACETAMIDO-URIDINE, RIBONUCLEASE A
著者Nachman, J, Wlodawer, A.
登録日1989-08-28
公開日1991-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of two covalent nucleoside derivatives of ribonuclease A.
Biochemistry, 29, 1990

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