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PDB: 12 件

4OJI
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Crystal Structure of Twister Ribozyme
分子名称: MAGNESIUM ION, RNA (52-MER)
著者Liu, Y, Wilson, T.J, McPhee, S.A, Lilley, D.M.J.
登録日2014-01-21
公開日2014-07-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure and mechanistic investigation of the twister ribozyme.
Nat.Chem.Biol., 10, 2014
6R47
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The structure of pistol ribozyme bound to magnesium
分子名称: MAGNESIUM ION, RNA, RNA (50-MER)
著者Lilley, D.M.J, Wilson, T.M, Liu, Y.
登録日2019-03-22
公開日2019-07-03
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Comparison of the Structures and Mechanisms of the Pistol and Hammerhead Ribozymes.
J.Am.Chem.Soc., 141, 2019
7T2X
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Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 2-chloro-4-((4-hydroxybenzyl)amino)-5-phenylthieno[2,3-d]pyrimidin-6-ol and GRIP Peptide
分子名称: Estrogen receptor, Nuclear receptor coactivator 2, S-(2-chloro-6-{[(4-hydroxyphenyl)methyl]amino}pyrimidin-4-yl) phenylethanethioate
著者Joiner, C, Sammeta, V.K.R, Norris, J.D, McDonnell, D.P, Wilson, T.M, Fanning, S.W.
登録日2021-12-06
公開日2022-06-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A New Chemotype of Chemically Tractable Nonsteroidal Estrogens Based on a Thieno[2,3- d ]pyrimidine Core.
Acs Med.Chem.Lett., 13, 2022
5CNQ
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BU of 5cnq by Molmil
Crystal structure of the Holliday junction-resolving enzyme GEN1 (WT) in complex with product DNA, Mg2+ and Mn2+ ions
分子名称: DNA (5'-D(*TP*GP*AP*GP*CP*GP*GP*TP*GP*GP*TP*TP*GP*GP*T)-3'), MANGANESE (II) ION, Nuclease-like protein, ...
著者Liu, Y.J, Freeman, A.D.J, Declais, A.C, Wilson, T.J, Gartner, A, Lilley, D.M.J.
登録日2015-07-17
公開日2015-12-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.
Cell Rep, 13, 2015
5C7Z
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AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
分子名称: AP-2 complex subunit mu, Integrin alpha-4
著者Owen, D.J, Evans, P.R, Wilson, T.A.
登録日2015-06-25
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
To Be Published
5CO8
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Crystal structure of the Holliday junction-resolving enzyme GEN1 (WT) in complex with product DNA and Mg2+ ion
分子名称: DNA (31-MER), DNA (5'-D(*AP*GP*AP*CP*TP*GP*CP*AP*GP*TP*TP*GP*AP*GP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*CP*GP*GP*TP*GP*GP*TP*TP*GP*GP*A)-3'), ...
著者Liu, Y.J, Freeman, A.D.J, Declais, A.C, Wilson, T.J, Gartner, A, Lilley, D.M.J.
登録日2015-07-20
公開日2016-01-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.
Cell Rep, 13, 2015
2MCO
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Structural studies on dinuclear ruthenium(II) complexes that bind diastereoselectively to an anti-parallel folded human telomere sequence
分子名称: SODIUM ION, human telomere quadruplex, tetrakis(2,2'-bipyridine-kappa~2~N~1~,N~1'~)(mu-tetrapyrido[3,2-a:2',3'-c:3'',2''-h:2''',3'''-j]phenazine-1kappa~2~N~4~,N~5~:2kappa~2~N~13~,N~14~)diruthenium(4+) L enantiomer
著者Williamson, M.P, Wilson, T, Thomas, J.A, Felix, V, Costa, P.J.
登録日2013-08-22
公開日2013-10-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere Sequence.
J.Med.Chem., 56, 2013
2MCC
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Structural studies on dinuclear ruthenium(II) complexes that bind diastereoselectively to an anti-parallel folded human telomere sequence
分子名称: human_telomere_quadruplex, tetrakis(2,2'-bipyridine-kappa~2~N~1~,N~1'~)(mu-tetrapyrido[3,2-a:2',3'-c:3'',2''-h:2''',3'''-j]phenazine-1kappa~2~N~4~,N~5~:2kappa~2~N~13~,N~14~)diruthenium(4+)
著者Williamson, M.P, Wilson, T, Thomas, J.A, Felix, V, Costa, P.J.
登録日2013-08-18
公開日2013-10-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere Sequence.
J.Med.Chem., 56, 2013
1PDU
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BU of 1pdu by Molmil
Ligand-binding domain of Drosophila orphan nuclear receptor DHR38
分子名称: nuclear hormone receptor HR38
著者Baker, K.D, Shewchuk, L.M, Korlova, T, Makishima, M, Hassell, A.M, Wisely, B, Caravella, J.A, Lambert, M.H, Wilson, T.M, Mangelsdorf, D.J.
登録日2003-05-20
公開日2003-06-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway.
Cell(Cambridge,Mass.), 113, 2003
5T5A
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Crystal Structure of the Twister Sister (TS) Ribozyme at 2.0 Angstrom
分子名称: DNA/RNA (71-MER), MAGNESIUM ION
著者Lilley, D.M.J, Liu, Y, Wilson, T.J.
登録日2016-08-30
公開日2017-03-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of a nucleolytic ribozyme that employs a catalytic metal ion.
Nat. Chem. Biol., 13, 2017
7SFO
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BU of 7sfo by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 3-(((2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino)methyl)phenol and GRIP Peptide
分子名称: 3-{[(2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino]methyl}phenol, Estrogen receptor, Nuclear receptor coactivator 2
著者Joyner, C, Reddy, V.K, Wilson, T, Fanning, S.W.
登録日2021-10-04
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Estrogen Receptor Alpha
To Be Published
3DY6
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PPARdelta complexed with an anthranilic acid partial agonist
分子名称: 2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid, IODIDE ION, Peroxisome proliferator-activated receptor delta
著者Lambert, M.L, Xu, R, Shearer, B.G, Wilson, T.M.
登録日2008-07-25
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Discovery of a novel class of PPARdelta partial agonists
Bioorg.Med.Chem.Lett., 18, 2008

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件を2024-11-13に公開中

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