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PDB: 243 件
1E8W
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Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine
分子名称: 3,5,7,3',4'-PENTAHYDROXYFLAVONE, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT
著者Walker, E.H, Pacold, M.E, Perisic, O, Stephens, L, Hawkins, P.T, Wymann, M.P, Williams, R.L.
登録日2000-10-03
公開日2000-11-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine
Mol.Cell, 6, 2000
1E8Z
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Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine
分子名称: PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT, STAUROSPORINE
著者Walker, E.H, Pacold, M.E, Perisic, O, Stephens, L, Hawkins, P.T, Wymann, M.P, Williams, R.L.
登録日2000-10-03
公開日2000-11-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine
Mol.Cell, 6, 2000
1E8Y
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Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine
分子名称: PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT
著者Walker, E.H, Pacold, M.E, Perisic, O, Stephens, L, Hawkins, P.T, Wymann, M.P, Williams, R.L.
登録日2000-10-03
公開日2000-11-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine
Mol.Cell, 6, 2000
1E90
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Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine
分子名称: 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT
著者Walker, E.H, Pacold, M.E, Perisic, O, Stephens, L, Hawkins, P.T, Wymann, M.P, Williams, R.L.
登録日2000-10-03
公開日2000-11-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine
Mol.Cell, 6, 2000
5WPR
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Crystal structure HpiC1 in C2 space group
分子名称: 12-epi-hapalindole C/U synthase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
著者Newmister, S.A, Li, S, Garcia-Borras, M, Sanders, J.N, Yang, S, Lowell, A.N, Yu, F, Smith, J.L, Williams, R.M, Houk, K.N, Sherman, D.H.
登録日2017-08-07
公開日2018-03-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis.
Nat. Chem. Biol., 14, 2018
5WPP
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Crystal structure HpiC1 W73M/K132M
分子名称: 12-epi-hapalindole C/U synthase, CALCIUM ION, TETRAETHYLENE GLYCOL, ...
著者Newmister, S.A, Li, S, Garcia-Borras, M, Sanders, J.N, Yang, S, Lowell, A.N, Yu, F, Smith, J.L, Williams, R.M, Houk, K.N, Sherman, D.H.
登録日2017-08-07
公開日2018-03-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis.
Nat. Chem. Biol., 14, 2018
5WPU
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Crystal structure HpiC1 Y101S
分子名称: 12-epi-hapalindole C/U synthase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION
著者Newmister, S.A, Li, S, Garcia-Borras, M, Sanders, J.N, Yang, S, Lowell, A.N, Yu, F, Smith, J.L, Williams, R.M, Houk, K.N, Sherman, D.H.
登録日2017-08-07
公開日2018-03-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis.
Nat. Chem. Biol., 14, 2018
5WPS
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Crystal structure HpiC1 Y101F
分子名称: 1,2-ETHANEDIOL, 12-epi-hapalindole C/U synthase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Newmister, S.A, Li, S, Garcia-Borras, M, Sanders, J.N, Yang, S, Lowell, A.N, Yu, F, Smith, J.L, Williams, R.M, Houk, K.N, Sherman, D.H.
登録日2017-08-07
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.389 Å)
主引用文献Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis.
Nat. Chem. Biol., 14, 2018
1E50
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AML1/CBFbeta complex
分子名称: CORE-BINDING FACTOR ALPHA SUBUNIT, CORE-BINDING FACTOR CBF-BETA
著者Warren, A.J, Bravo, J, Williams, R.L, Rabbits, T.H.
登録日2000-07-13
公開日2001-07-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for the Heterodimeric Interaction between the Acute Leukaemia-Associated Transcription Factors Aml1 and Cbfbeta
Embo J., 19, 2000
7KR3
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Human DNA Ligase 1(E346A/E592A) Bound to a bulged DNA substrate
分子名称: ACETATE ION, ADENOSINE MONOPHOSPHATE, DNA (5'-D(*AP*AP*TP*GP*TP*CP*TP*GP*CP*CP*CP*C)-3'), ...
著者Tumbale, P.P, Williams, R.S.
登録日2020-11-18
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.778 Å)
主引用文献High-fidelity DNA ligation enforces accurate Okazaki fragment maturation during DNA replication.
Nat Commun, 12, 2021
7KR4
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Human DNA Ligase 1(E346A/E592A) Bound to a nicked DNA substrate control duplex
分子名称: ACETATE ION, ADENOSINE MONOPHOSPHATE, DNA (5'-D(*AP*AP*TP*GP*TP*CP*TP*GP*CP*CP*C)-3'), ...
著者Tumbale, P.P, Williams, R.S.
登録日2020-11-18
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献High-fidelity DNA ligation enforces accurate Okazaki fragment maturation during DNA replication.
Nat Commun, 12, 2021
1DJH
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PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH BARIUM
分子名称: ACETATE ION, BARIUM ION, PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C, ...
著者Essen, L.-O, Perisic, O, Williams, R.L.
登録日1996-09-25
公開日1997-07-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1.
Biochemistry, 36, 1997
1DJI
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PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH CALCIUM
分子名称: ACETATE ION, CALCIUM ION, PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C, ...
著者Essen, L.-O, Perisic, O, Williams, R.L.
登録日1996-09-25
公開日1997-07-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1.
Biochemistry, 36, 1997
1DJG
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PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH LANTHANUM
分子名称: ACETATE ION, LANTHANUM (III) ION, PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C, ...
著者Essen, L.-O, Perisic, O, Williams, R.L.
登録日1996-09-25
公開日1997-07-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1.
Biochemistry, 36, 1997
7JL5
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BU of 7jl5 by Molmil
Crystal structure of human NEIL3 tandem zinc finger GRF domains
分子名称: Endonuclease 8-like 3, ZINC ION
著者Rodriguez, A.A, Wojtaszek, J.L, Williams, R.S, Eichman, B.F.
登録日2020-07-29
公開日2020-09-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An autoinhibitory role for the GRF zinc finger domain of DNA glycosylase NEIL3.
J.Biol.Chem., 295, 2020
7L34
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Human DNA Ligase 1 - R641L nicked DNA complex
分子名称: ADENOSINE MONOPHOSPHATE, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
著者Tumbale, P.P, Williams, R.S, Schellenberg, M.S.
登録日2020-12-17
公開日2021-01-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献LIG1 syndrome mutations remodel a cooperative network of ligand binding interactions to compromise ligation efficiency.
Nucleic Acids Res., 49, 2021
7L35
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Human DNA Ligase 1 - R771W nicked DNA complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
著者Tumbale, P.P, Williams, R.S, Schellenberg, M.S.
登録日2020-12-17
公開日2021-01-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献LIG1 syndrome mutations remodel a cooperative network of ligand binding interactions to compromise ligation efficiency.
Nucleic Acids Res., 49, 2021
5W7H
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Supercharged arPTE variant R5
分子名称: Phosphotriesterase, ZINC ION
著者Campbell, E, Grant, J, Wang, Y, Sandhu, M, Williams, R.J, Nisbet, D.R, Perriman, A, Lupton, D, Jackson, C.J.
登録日2017-06-19
公開日2019-01-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Hydrogel-Immobilized Supercharged Proteins
Adv Biosyst, 2018

221051

件を2024-06-12に公開中

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