5WPR

Crystal structure HpiC1 in C2 space group

Summary for 5WPR

• Entry DOI: 10.2210/pdb5wpr/pdb
• Related: 5WPP
• Descriptor: 12-epi-hapalindole C/U synthase, CALCIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• Functional Keywords: isomerase, cyclase
• Biological source: Fischerella sp. ATCC 43239
• Total number of polymer chains: 1
• Total formula weight: 24805.55

Authors

Newmister, S.A.,Li, S.,Garcia-Borras, M.,Sanders, J.N.,Yang, S.,Lowell, A.N.,Yu, F.,Smith, J.L.,Williams, R.M.,Houk, K.N.,Sherman, D.H. (deposition date: 2017-08-07, release date: 2018-03-07, Last modification date: 2023-10-04)

• Primary citation: Newmister, S.A.,Li, S.,Garcia-Borras, M.,Sanders, J.N.,Yang, S.,Lowell, A.N.,Yu, F.,Smith, J.L.,Williams, R.M.,Houk, K.N.,Sherman, D.H.; Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis.; Nat. Chem. Biol., 14:345-351, 2018; PubMed: 29531360; DOI: 10.1038/s41589-018-0003-x

Experimental method

X-RAY DIFFRACTION (1.49 Å)