2FEE
 
 | | Structure of the Cl-/H+ exchanger CLC-ec1 from E.Coli in NaBr | | 分子名称: | Fab fragment, heavy chain, light chain, ... | | 著者 | Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. | | 登録日 | 2005-12-15 | | 公開日 | 2006-01-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
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2HT2
 | | Structure of the Escherichia coli ClC chloride channel Y445H mutant and Fab complex | | 分子名称: | BROMIDE ION, Fab fragment, heavy chain, ... | | 著者 | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | 登録日 | 2006-07-25 | | 公開日 | 2006-09-19 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | | 主引用文献 | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
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2HLF
 | | Structure of the Escherichis coli ClC chloride channel Y445E mutant and Fab complex | | 分子名称: | BROMIDE ION, Fab Fragment, Heavy chain, ... | | 著者 | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | 登録日 | 2006-07-07 | | 公開日 | 2006-09-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger
J.Mol.Biol., 362, 2006
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2HT3
 | | Structure of the Escherichia coli ClC chloride channel Y445L mutant and Fab complex | | 分子名称: | BROMIDE ION, Fab fragment, Heavy chain, ... | | 著者 | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | 登録日 | 2006-07-25 | | 公開日 | 2006-09-19 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
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2HT4
 | | Structure of the Escherichia coli ClC chloride channel Y445W mutant and Fab complex | | 分子名称: | BROMIDE ION, Fab fragment, Heavy chain, ... | | 著者 | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | 登録日 | 2006-07-25 | | 公開日 | 2006-09-19 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
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2HTL
 | | Structure of the Escherichia coli ClC chloride channel Y445F mutant and Fab complex | | 分子名称: | BROMIDE ION, Fab fragment, Heavy chain, ... | | 著者 | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | 登録日 | 2006-07-26 | | 公開日 | 2006-09-19 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
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2HTK
 | | Structure of the Escherichia coli ClC chloride channel Y445A mutant and Fab complex | | 分子名称: | BROMIDE ION, Fab fragment, Heavy chain, ... | | 著者 | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | 登録日 | 2006-07-26 | | 公開日 | 2006-09-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
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6GWX
 | | Stabilising and Understanding a Miniprotein by Rational Design. | | 分子名称: | Optimised PPa-TYR | | 著者 | Porter Goff, K.L, Williams, C, Baker, E.G, Nicol, D, Samphire, J.L, Zieleniewski, F.L, Crump, M.P, Woolfson, D.N. | | 登録日 | 2018-06-26 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Stabilizing and Understanding a Miniprotein by Rational Redesign.
Biochemistry, 58, 2019
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2PNG
 | | Type I rat fatty acid synthase acyl carrier protein (ACP) domain | | 分子名称: | Fatty acid synthase (EC 2.3.1.85) | | 著者 | Ploskon, E.A, Arthur, C.J, Evans, S.E, Williams, C, Crosby, J, Crump, M.P. | | 登録日 | 2007-04-24 | | 公開日 | 2007-06-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Mammalian type I Fatty Acid synthase acyl carrier protein domain does not sequester acyl chains.
J.Biol.Chem., 283, 2008
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6G1C
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6G1N
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6G26
 | | The crystal structure of the Burkholderia pseudomallei HicAB complex | | 分子名称: | 1,2-ETHANEDIOL, HicA, HicB, ... | | 著者 | Winter, A.J, Isupov, M.N, Williams, C, Crump, M.P. | | 登録日 | 2018-03-22 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | The molecular basis of protein toxin HicA-dependent binding of the protein antitoxin HicB to DNA.
J. Biol. Chem., 293, 2018
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6FXD
 | | Crystal structure of MupZ from Pseudomonas fluorescens | | 分子名称: | MupZ | | 著者 | Wang, L, Parnell, A, Williams, C, Bakar, N.A, van der Kamp, M.W, Simpson, T.J, Race, P.R, Crump, M.P, Willis, C.L. | | 登録日 | 2018-03-08 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | A Rieske oxygenase/epoxide hydrolase-catalysed reaction cascade creates oxygen heterocycles in mupirocin biosynthesis
Nat Catal, 2018
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6Z30
 | | Human cation-independent mannose 6-phosphate/ IGF2 receptor domains 9-10 | | 分子名称: | Cation-independent mannose-6-phosphate receptor, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Bochel, A.J, Williams, C, Crump, M.P. | | 登録日 | 2020-05-19 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.
Structure, 28, 2020
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6Z31
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6Z32
 | | Human cation-independent mannose 6-phosphate/IGF2 receptor domains 7-11 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cation-independent mannose-6-phosphate receptor, SULFATE ION, ... | | 著者 | Bochel, A.J, Williams, C, McCoy, A.J, Hoppe, H, Winter, A.J, Nicholls, R.D, Harlos, K, Jones, Y.E, Berger, I, Hassan, B, Crump, M.P. | | 登録日 | 2020-05-19 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.47 Å) | | 主引用文献 | Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.
Structure, 28, 2020
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4I8A
 | | Alanine-glyoxylate aminotransferase variant S187F | | 分子名称: | GLYCEROL, Serine-pyruvate aminotransferase | | 著者 | Fodor, K, Oppici, E, Williams, C, Cellini, B, Wilmanns, M. | | 登録日 | 2012-12-03 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications.
Proteins, 81, 2013
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1Q1J
 | | Crystal Structure Analysis of anti-HIV-1 Fab 447-52D in complex with V3 peptide | | 分子名称: | Fab 447-52D, heavy chain, light chain, ... | | 著者 | Stanfield, R.L, Gorny, M.K, Williams, C, Zolla-Pazner, S, Wilson, I.A. | | 登録日 | 2003-07-21 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D.
Structure, 12, 2004
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2B4K
 | | Acetobacter turbidans alpha-amino acid ester hydrolase complexed with phenylglycine | | 分子名称: | Alpha-amino acid ester hydrolase, D-PHENYLGLYCINE, GLYCEROL | | 著者 | Barends, T.R.M, Polderman-Tijmes, J.J, Jekel, P.A, Williams, C, Wybenga, G, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2005-09-26 | | 公開日 | 2005-12-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme.
J.Biol.Chem., 281, 2006
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2CNR
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5IEI
 | | X-ray crystallographic structure of a high affinity IGF2 antagonist (Domain11 AB5 RHH) based on human IGF2R domain 11 | | 分子名称: | 1,2-ETHANEDIOL, Cation-independent mannose-6-phosphate receptor, GLYCEROL, ... | | 著者 | Nicholls, R.D, Williams, C, Strickland, M, Frago, S, Hassan, A.B, Crump, M.P. | | 登録日 | 2016-02-25 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016
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2MVV
 | | Solution Structure of the 5-phenyl-3-oxo-pentyl Actinorhodin Acyl Carrier Protein from Streptomyces coelicolor | | 分子名称: | Actinorhodin polyketide synthase acyl carrier protein, N~3~-{(2S)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-{2-[(3-oxo-5-phenylpentyl)sulfanyl]ethyl}-beta-alaninamide | | 著者 | Dong, X, Bailey, C, Williams, C, Crosby, J, Simpson, T.J, Willis, C.L, Crump, M.P. | | 登録日 | 2014-10-15 | | 公開日 | 2015-10-21 | | 実験手法 | SOLUTION NMR | | 主引用文献 | ACP-ligand recognition: Selection of derivatized aromatic biosynthetic intermediates
To be Published
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2MVU
 | | Solution Structure of the 3,7-dioxo-octyl Actinorhodin Acyl Carrier Protein from Streptomyces coelicolor | | 分子名称: | Actinorhodin polyketide synthase acyl carrier protein, N~3~-{(2S)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-{2-[(3,7-dioxooctyl)sulfanyl]ethyl}-beta-alaninamide | | 著者 | Dong, X, Bailey, C, Williams, C, Crosby, J, Simpson, T.J, Willis, C.L, Crump, M.P. | | 登録日 | 2014-10-15 | | 公開日 | 2015-10-21 | | 実験手法 | SOLUTION NMR | | 主引用文献 | ACP-ligand recognition: Selection of derivatized aromatic biosynthetic intermediates
To be Published
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2L22
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2LLA
 | | NMR solution structure ensemble of domain 11 of the echidna M6P/IGF2R receptor | | 分子名称: | Mannose-6-phosphate/insulin-like growth factor II receptor | | 著者 | Strickland, M, Crump, M.P, Williams, C, Rezgui, D, Ellis, R.Z, Hoppe, H, Frago, S, Prince, S.N, Zaccheo, O.J, Forbes, B.E, Jones, E, Hassan, A.Z, Wattana-Amorn, P. | | 登録日 | 2011-11-05 | | 公開日 | 2012-11-07 | | 最終更新日 | 2012-12-12 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science, 338, 2012
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