2GX5
 
 | | N-terminal GAF domain of transcriptional pleiotropic repressor CodY | | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, GTP-sensing transcriptional pleiotropic repressor codY, ... | | 著者 | Wilkinson, A.J, Levdikov, V.M, Blagova, E.V. | | 登録日 | 2006-05-08 | | 公開日 | 2007-04-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | The structure of CodY, a GTP- and isoleucine-responsive regulator of stationary phase and virulence in gram-positive bacteria.
J.Biol.Chem., 281, 2006
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2HGV
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5LOE
 | | Structure of full length Cody from Bacillus subtilis in complex with Ile | | 分子名称: | GTP-sensing transcriptional pleiotropic repressor CodY, ISOLEUCINE | | 著者 | Wilkinson, A.J, Levdikov, V.M, Blagova, E.V. | | 登録日 | 2016-08-09 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of the Branched-chain Amino Acid and GTP-sensing Global Regulator, CodY, from Bacillus subtilis.
J. Biol. Chem., 292, 2017
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5LOJ
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5LOO
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5LNH
 | | Structure of full length Unliganded CodY from Bacillus subtilis | | 分子名称: | GTP-sensing transcriptional pleiotropic repressor CodY, SULFATE ION | | 著者 | Wilkinson, A.J, Levdikov, V.M, Blagova, E.V. | | 登録日 | 2016-08-04 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of the Branched-chain Amino Acid and GTP-sensing Global Regulator, CodY, from Bacillus subtilis.
J. Biol. Chem., 292, 2017
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8BPT
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2RKM
 | | STRUCTURE OF OPPA COMPLEXED WITH LYS-LYS | | 分子名称: | LYSINE, OLIGO-PEPTIDE BINDING PROTEIN, URANYL (VI) ION | | 著者 | Sleigh, S.H, Tame, J.R.H, Wilkinson, A.J. | | 登録日 | 1997-03-25 | | 公開日 | 1997-07-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Peptide binding in OppA, the crystal structures of the periplasmic oligopeptide binding protein in the unliganded form and in complex with lysyllysine.
Biochemistry, 36, 1997
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5AEO
 | | Virulence-associated protein VapG from the intracellular pathogen Rhodococcus equi | | 分子名称: | POTASSIUM ION, R. EQUI VAPG PROTEIN | | 著者 | Okoko, T, Blagova, E.V, Whittingham, J.L, Dover, L.G, Wilkinson, A.J. | | 登録日 | 2015-01-07 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Characterisation of the Virulence-Associated Protein Vapg from the Horse Pathogen Rhodococcus Equi.
Vet.Microbiol., 179, 2015
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3DD6
 | | Crystal structure of Rph, an exoribonuclease from Bacillus anthracis at 1.7 A resolution | | 分子名称: | Ribonuclease PH, SULFATE ION | | 著者 | Rawlings, A.E, Blagova, E.V, Levdikov, V.M, Fogg, M.J, Wilson, K.S, Wilkinson, A.J, Structural Proteomics in Europe 2 (SPINE-2) | | 登録日 | 2008-06-05 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | The structure of Rph, an exoribonuclease from Bacillus anthracis, at 1.7 A resolution.
Acta Crystallogr.,Sect.F, 65, 2009
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4PEM
 | | Crystal Structure of S1G mutant of Penicillin G Acylase from Kluyvera citrophila | | 分子名称: | CALCIUM ION, Penicillin G acylase Alpha, Penicillin G acylase Beta | | 著者 | Ramasamy, S, Varshney, N.K, Brannigan, J.A, Wilkinson, A.J, Suresh, C.G. | | 登録日 | 2014-04-24 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of S1G mutant of Penicillin G Acylase from Kluyvera citrophilla
To be Published
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4PEL
 | | S1C mutant of Penicillin G acylase from Kluyvera citrophila | | 分子名称: | CALCIUM ION, Penicillin G acylase subunit alpha, Penicillin G acylase subunit beta | | 著者 | Ramasamy, S, Chand, D, Varshney, N.K, Brannigan, J.A, Wilkinson, A.J, Suresh, C.G. | | 登録日 | 2014-04-24 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Penicillin G acylase
To Be Published
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2TGF
 | | THE SOLUTION STRUCTURE OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA | | 分子名称: | TRANSFORMING GROWTH FACTOR-ALPHA | | 著者 | Harvey, T.S, Wilkinson, A.J, Tappin, M.J, Cooke, R.M, Campbell, I.D. | | 登録日 | 1991-01-23 | | 公開日 | 1993-04-15 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of human transforming growth factor alpha.
Eur.J.Biochem., 198, 1991
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1MYJ
 | | DISTAL POLARITY IN LIGAND BINDING TO MYOGLOBIN: STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF A THREONINE68(E11) MUTANT | | 分子名称: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | 著者 | Smerdon, S.J, Oldfield, T.J, Wilkinson, A.J, Dauter, Z, Petratos, K, Wilson, K.S. | | 登録日 | 1992-02-27 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Distal pocket polarity in ligand binding to myoglobin: structural and functional characterization of a threonine68(E11) mutant.
Biochemistry, 30, 1991
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1MYI
 | | HIGH RESOLUTION X-RAY STRUCTURES OF PIG METMYOGLOBIN AND TWO CD3 MUTANTS MB(LYS45-> ARG) AND MB(LYS45-> SER) | | 分子名称: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Smerdon, S.J, Oldfield, T.J, Wilkinson, A.J, Dauter, Z, Petratos, K, Wilson, K.S. | | 登録日 | 1992-02-27 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | High-resolution X-ray structures of pig metmyoglobin and two CD3 mutants: Mb(Lys45----Arg) and Mb(Lys45----Ser).
Biochemistry, 31, 1992
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2FYI
 | | Crystal Structure of the Cofactor-Binding Domain of the Cbl Transcriptional Regulator | | 分子名称: | HTH-type transcriptional regulator cbl | | 著者 | Stec, E, Neumann, P, Wilkinson, A.J, Brzozowski, A.M, Bujacz, G.D. | | 登録日 | 2006-02-08 | | 公開日 | 2006-02-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Basis of the Sulphate Starvation Response in E. coli: Crystal Structure and Mutational Analysis of the Cofactor-binding Domain of the Cbl Transcriptional Regulator.
J.Mol.Biol., 364, 2006
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9FDD
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4UFW
 | | Plasmodium vivax N-myristoyltransferase in complex with a pyridyl inhibitor (compound 22) | | 分子名称: | 2-oxopentadecyl-CoA, 4-chloranyl-N-[2-(3-methoxyphenyl)ethanimidoyl]-2-piperidin-4-yloxy-benzamide, CHLORIDE ION, ... | | 著者 | Yu, Z, Brannigan, J.A, Rangachari, K, Heal, W.P, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | | 登録日 | 2015-03-19 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Discovery of Pyridyl-Based Inhibitors of Plasmodium Falciparum N-Myristoyltransferase
Medchemcomm, 6, 2015
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4UFX
 | | Plasmodium vivax N-myristoyltransferase in complex with a pyridyl inhibitor (compound 19) | | 分子名称: | 2-oxopentadecyl-CoA, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Yu, Z, Brannigan, J.A, Rangachari, K, Heal, W.P, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | | 登録日 | 2015-03-19 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Discovery of Pyridyl-Based Inhibitors of Plasmodium Falciparum N-Myristoyltransferase
Medchemcomm, 6, 2015
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4UFV
 | | Plasmodium vivax N-myristoyltransferase in complex with a pyridyl inhibitor (compound 18) | | 分子名称: | 2-oxopentadecyl-CoA, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Yu, Z, Brannigan, J.A, Rangachari, K, Heal, W.P, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | | 登録日 | 2015-03-19 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Discovery of Pyridyl-Based Inhibitors of Plasmodium Falciparum N-Myristoyltransferase
Medchemcomm, 6, 2015
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6ZM3
 | | The structure of an E2 ubiquitin-conjugating complex (UBC2-UEV1) essential for Leishmania amastigote differentiation | | 分子名称: | Putative ubiquitin-conjugating enzyme e2, Ubiquitin-conjugating enzyme-like protein | | 著者 | Burge, R.J, Dodson, E.J, Wilkinson, A.J, Mottram, J.C. | | 登録日 | 2020-07-01 | | 公開日 | 2020-07-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex.
Plos Pathog., 16, 2020
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1MWC
 | | WILD TYPE MYOGLOBIN WITH CO | | 分子名称: | CARBON MONOXIDE, PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Murshudov, G.N, Krzywda, S, Brzozowski, A.M, Jaskolski, M, Scott, E.E, Klizas, S.A, Gibson, Q.H, Olson, J.S, Wilkinson, A.J. | | 登録日 | 1998-08-12 | | 公開日 | 1998-08-19 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Stabilizing bound O2 in myoglobin by valine68 (E11) to asparagine substitution.
Biochemistry, 37, 1998
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1MWD
 | | WILD TYPE DEOXY MYOGLOBIN | | 分子名称: | PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Murshudov, G.N, Krzywda, S, Brzozowski, A.M, Jaskolski, M, Scott, E.E, Klizas, A.A, Gibson, Q.H, Olson, J.S, Wilkinson, A.J. | | 登録日 | 1998-08-11 | | 公開日 | 1998-08-19 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Stabilizing bound O2 in myoglobin by valine68 (E11) to asparagine substitution.
Biochemistry, 37, 1998
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2OLB
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7ATR
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