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PDB: 188 件

5O4V
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P.vivax NMT with aminomethylindazole and quinoline inhibitors bound
分子名称: 1-[5-(4-fluoranyl-2-methyl-phenyl)-1~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, 2-oxopentadecyl-CoA, CHLORIDE ION, ...
著者Brannigan, J.A, Wilkinson, A.J.
登録日2017-05-31
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus.
Nat Chem, 10, 2018
1OLC
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OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH LYS-LYS-LYS-ALA
分子名称: LYS-LYS-LYS-ALA, OLIGO-PEPTIDE BINDING PROTEIN, URANYL (VI) ION
著者Tame, J, Wilkinson, A.J.
登録日1995-09-10
公開日1996-01-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structures of the oligopeptide-binding protein OppA complexed with tripeptide and tetrapeptide ligands.
Structure, 3, 1995
2WWF
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Plasmodium falciparum thymidylate kinase in complex with TMP and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, SODIUM ION, ...
著者Whittingham, J.L, Carrero-Lerida, J, Brannigan, J.A, Ruiz-Perez, L.M, Silva, A.P.G, Fogg, M.J, Wilkinson, A.J, Gilbert, I.H, Wilson, K.S, Gonzalez-Pacanowska, D.
登録日2009-10-23
公開日2010-04-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural Basis for the Efficient Phosphorylation of Aztmp and Dgmp by Plasmodium Falciparum Type I Thymidylate Kinase.
Biochem.J., 428, 2010
2WWI
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Plasmodium falciparum thymidylate kinase in complex with AZTMP and ADP
分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, THYMIDILATE KINASE, ...
著者Whittingham, J.L, Carrero-Lerida, J, Brannigan, J.A, Ruiz-Perez, L.M, Silva, A.P.G, Fogg, M.J, Wilkinson, A.J, Gilbert, I.H, Wilson, K.S, Gonzalez-Pacanowska, D.
登録日2009-10-23
公開日2010-04-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Structural Basis for the Efficient Phosphorylation of Aztmp and Dgmp by Plasmodium Falciparum Type I Thymidylate Kinase.
Biochem.J., 428, 2010
2WWH
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Plasmodium falciparum thymidylate kinase in complex with AP5dT
分子名称: P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, SODIUM ION, THYMIDILATE KINASE, ...
著者Whittingham, J.L, Carrero-Lerida, J, Brannigan, J.A, Ruiz-Perez, L.M, Silva, A.P.G, Fogg, M.J, Wilkinson, A.J, Gilbert, I.H, Wilson, K.S, Gonzalez-Pacanowska, D.
登録日2009-10-23
公開日2010-04-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for the Efficient Phosphorylation of Aztmp and Dgmp by Plasmodium Falciparum Type I Thymidylate Kinase.
Biochem.J., 428, 2010
2C40
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CRYSTAL STRUCTURE OF INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE FROM BACILLUS ANTHRACIS AT 2.2A RESOLUTION
分子名称: CALCIUM ION, INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE FAMILY PROTEIN, alpha-D-ribofuranose
著者Moroz, O.V, Blagova, E.V, Fogg, M.J, Levdikov, V.M, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S.
登録日2005-10-13
公開日2007-02-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of Inosine-Uridine Preferring Nucleoside Hydrolase from Bacillus Anthracis at 2.2A Resolution
To be Published
1PMB
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BU of 1pmb by Molmil
THE DETERMINATION OF THE CRYSTAL STRUCTURE OF RECOMBINANT PIG MYOGLOBIN BY MOLECULAR REPLACEMENT AND ITS REFINEMENT
分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
著者Smerdon, S.J, Oldfield, T.J, Dodson, E.J, Dodson, G.G, Hubbard, R.E, Wilkinson, A.J.
登録日1989-11-27
公開日1990-01-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Determination of the crystal structure of recombinant pig myoglobin by molecular replacement and its refinement.
Acta Crystallogr.,Sect.B, 46, 1990
2YAL
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SinR, Master Regulator of biofilm formation in Bacillus subtilis
分子名称: HTH-TYPE TRANSCRIPTIONAL REGULATOR SINR, NICKEL (II) ION
著者Colledge, V.L, Fogg, M.J, Levdikov, V.M, Leech, A, Dodson, E.J, Wilkinson, A.J.
登録日2011-02-23
公開日2011-06-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structure and Organisation of Sinr, the Master Regulator of Biofilm Formation in Bacillus Subtilis.
J.Mol.Biol., 411, 2011
1UZ9
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BU of 1uz9 by Molmil
Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting insulins.
分子名称: (2S)-2-AMINO-6-({(4R)-4-[(10R,13S)-10,13-DIMETHYL-3-OXOHEXADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL]PENTANOYL}AMINO)HEXANOIC ACID, CHLORIDE ION, INSULIN, ...
著者Whittingham, J.L, Jonassen, I, Havelund, S, Roberts, S.M, Dodson, E.J, Verma, C.S, Wilkinson, A.J, Dodson, G.G.
登録日2004-03-08
公開日2005-03-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallographic and Solution Studies of N-Lithocholyl Insulin: A New Generation of Prolonged-Acting Human Insulins
Biochemistry, 43, 2004
1OLA
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THE STRUCTURAL BASIS OF MULTISPECIFICITY IN THE OLIGOPEPTIDE-BINDING PROTEIN OPPA
分子名称: OLIGO-PEPTIDE BINDING PROTEIN, PEPTIDE VAL-LYS-PRO-GLY, URANYL (VI) ION
著者Tame, J, Wilkinson, A.J.
登録日1994-04-26
公開日1994-07-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structural basis of sequence-independent peptide binding by OppA protein.
Science, 264, 1994
1UOH
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HUMAN GANKYRIN
分子名称: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10
著者Krzywda, S, Brzozowski, A.M, Wilkinson, A.J.
登録日2003-09-17
公開日2003-10-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of Gankyrin, an Oncoprotein Found in Complexes with Cyclin-Dependent Kinase 4, a 19 S Proteasomal ATPase Regulator, and the Tumor Suppressors Rb and P53
J.Biol.Chem., 279, 2004
2YND
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BU of 2ynd by Molmil
Plasmodium vivax N-myristoyltransferase in complex with a pyrazole sulphonamide inhibitor.
分子名称: 2,6-dichloro-4-(2-piperazin-1-ylpyridin-4-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide, 2-oxopentadecyl-CoA, CHLORIDE ION, ...
著者Wright, M.H, Clough, B, Rackham, M.D, Brannigan, J.A, Grainger, M, Bottrill, A.R, Heal, W.P, Broncel, M, Serwa, R.A, Mann, D, Leatherbarrow, R.J, Wilkinson, A.J, Holder, A.A, Tate, E.W.
登録日2012-10-13
公開日2014-01-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Validation of N-Myristoyltransferase as an Antimalarial Drug Target Using an Integrated Chemical Biology Approach.
Nat.Chem., 6, 2014
2YNE
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BU of 2yne by Molmil
Plasmodium vivax N-myristoyltransferase in complex with a benzothiophene inhibitor
分子名称: 2-(3-piperidin-4-yloxy-1-benzothiophen-2-yl)-5-[(1,3,5-trimethylpyrazol-4-yl)methyl]-1,3,4-oxadiazole, 2-oxopentadecyl-CoA, CHLORIDE ION, ...
著者Wright, M.H, Clough, B, Rackham, M.D, Brannigan, J.A, Grainger, M, Bottrill, A.R, Heal, W.P, Broncel, M, Serwa, R.A, Mann, D, Leatherbarrow, R.J, Wilkinson, A.J, Holder, A.A, Tate, E.W.
登録日2012-10-13
公開日2014-01-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Validation of N-Myristoyltransferase as an Antimalarial Drug Target Using an Integrated Chemical Biology Approach.
Nat.Chem., 6, 2014
2YNC
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Plasmodium vivax N-myristoyltransferase in complex with YnC12-CoA thioester.
分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, ...
著者Wright, M.H, Clough, B, Rackham, M.D, Brannigan, J.A, Grainger, M, Bottrill, A.R, Heal, W.P, Broncel, M, Serwa, R.A, Mann, D, Leatherbarrow, R.J, Wilkinson, A.J, Holder, A.A, Tate, E.W.
登録日2012-10-13
公開日2014-01-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Validation of N-Myristoyltransferase as an Antimalarial Drug Target Using an Integrated Chemical Biology Approach.
Nat.Chem., 6, 2014
2BZB
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BU of 2bzb by Molmil
NMR Solution Structure of a protein aspartic acid phosphate phosphatase from Bacillus Anthracis
分子名称: CONSERVED DOMAIN PROTEIN
著者Grenha, R, Rzechorzek, N.J, Brannigan, J.A, Ab, E, Folkers, G.E, De Jong, R.N, Diercks, T, Wilkinson, A.J, Kaptein, R, Wilson, K.S.
登録日2005-08-14
公開日2006-09-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural characterization of Spo0E-like protein-aspartic acid phosphatases that regulate sporulation in bacilli.
J. Biol. Chem., 281, 2006
2C0S
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BU of 2c0s by Molmil
NMR Solution Structure of a protein aspartic acid phosphate phosphatase from Bacillus Anthracis
分子名称: CONSERVED DOMAIN PROTEIN
著者Grenha, R, Rzechorzek, N.J, Brannigan, J.A, Ab, E, Folkers, G.E, De Jong, R.N, Diercks, T, Wilkinson, A.J, Kaptein, R, Wilson, K.S.
登録日2005-09-07
公開日2006-09-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural characterization of Spo0E-like protein-aspartic acid phosphatases that regulate sporulation in bacilli.
J. Biol. Chem., 281, 2006
2V36
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Crystal structure of gamma-glutamyl transferase from Bacillus subtilis
分子名称: GAMMA-GLUTAMYLTRANSPEPTIDASE LARGE CHAIN, GAMMA-GLUTAMYLTRANSPEPTIDASE SMALL CHAIN
著者Sharath, B, Prabhune, A.A, Suresh, C.G, Wilkinson, A.J, Brannigan, J.A.
登録日2007-06-13
公開日2008-07-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of Gamma-Glutamyl Transferase
To be Published
1XOC
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The structure of the oligopeptide-binding protein, AppA, from Bacillus subtilis in complex with a nonapeptide.
分子名称: Nonapeptide VDSKNTSSW, Oligopeptide-binding protein appA, ZINC ION
著者Levdikov, V.M, Blagova, E.V, Brannigan, J.A, Wright, L, Vagin, A.A, Wilkinson, A.J.
登録日2004-10-06
公開日2005-01-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The structure of the oligopeptide-binding protein, AppA, from Bacillus subtilis in complex with a nonapeptide.
J.Mol.Biol., 345, 2005
2D30
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Crystal Structure of Cytidine Deaminase Cdd-2 (BA4525) from Bacillus Anthracis at 2.40A Resolution
分子名称: ZINC ION, cytidine deaminase
著者Levdikov, V.M, Blagova, E.V, Fogg, M.J, Brannigan, J.A, Moroz, O.V, Wilkinson, A.J, Wilson, K.S, Structural Proteomics in Europe (SPINE)
登録日2005-09-21
公開日2006-09-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Cytidine Deaminase Cdd-2 (BA4525) from Bacillus Anthracis at 2.40A Resolution
To be Published
2BTU
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Crystal structure of Phosphoribosylformylglycinamidine cyclo-ligase from Bacillus Anthracis at 2.3A resolution.
分子名称: PHOSPHORIBOSYL-AMINOIMIDAZOLE SYNTHETASE
著者Moroz, O.V, Blagova, E.V, Levdikov, V.M, Fogg, M.J, Lebedev, A.A, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S.
登録日2005-06-07
公開日2006-08-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal Structure of Phosphoribosylformylglycinamidine Cyclo-Ligase from Bacillus Anthracis at 2.3A Resolution.
To be Published
2CHU
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CeuE in complex with mecam
分子名称: ENTEROCHELIN UPTAKE PERIPLASMIC BINDING PROTEIN, FE (III) ION, N,N',N''-[BENZENE-1,3,5-TRIYLTRIS(METHYLENE)]TRIS(2,3-DIHYDROXYBENZAMIDE), ...
著者Muller, A, Wilkinson, A.J, Wilson, K.S, Duhme-Klair, A.K.
登録日2006-03-16
公開日2006-08-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An [{Fe(Mecam)}(2)](6-) Bridge in the Crystal Structure of a Ferric Enterobactin Binding Protein.
Angew.Chem.Int.Ed.Engl., 45, 2006
2BW2
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BofC from Bacillus subtilis
分子名称: BYPASS OF FORESPORE C
著者Patterson, H.M, Brannigan, J.A, Cutting, S.M, Wilson, K.S, Wilkinson, A.J, Ab, E, Diercks, T, Folkers, G.E, de Jong, R.N, Truffault, V, Kaptein, R.
登録日2005-07-08
公開日2005-09-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The structure of bypass of forespore C, an intercompartmental signaling factor during sporulation in Bacillus.
J. Biol. Chem., 280, 2005
1YPF
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Crystal Structure of GuaC (BA5705) from Bacillus anthracis at 1.8 A Resolution
分子名称: GMP reductase
著者Grenha, R, Levdikov, V.M, Blagova, E.V, Fogg, M.J, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S, Structural Proteomics in Europe (SPINE)
登録日2005-01-31
公開日2006-02-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of GuaC (BA5705) from Bacillus anthracis at 1.8 A Resolution.
To be Published
2WC8
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BU of 2wc8 by Molmil
S100A12 complex with zinc in the absence of calcium
分子名称: CITRIC ACID, PROTEIN S100-A12, SODIUM ION, ...
著者Moroz, O.V, Blagova, E.V, Wilkinson, A.J, Wilson, K.S, Bronstein, I.B.
登録日2009-03-10
公開日2009-06-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献The Crystal Structures of Human S100A12 in Apo Form and in Complex with Zinc: New Insights Into S100A12 Oligomerisation.
J.Mol.Biol., 391, 2009
1XP3
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Crystal Structure of Endonuclease IV (BA4508) from Bacillus anthracis at 2.57A Resolution.
分子名称: SULFATE ION, ZINC ION, endonuclease IV
著者Fogg, M.J, Levdikov, V.M, Blagova, E.V, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S, Structural Proteomics in Europe (SPINE)
登録日2004-10-08
公開日2005-10-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Crystal Structure of Endonuclease IV (BA4508) from Bacillus anthracis at 2.57A Resolution.
To be Published

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