3RRM
 
 | | S. cerevisiae dbp5 l327v bound to nup159, gle1 h337r, ip6 and adp | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | 登録日 | 2011-04-29 | | 公開日 | 2011-05-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature, 472, 2011
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8ODW
 | | Crystal structure of LbmA Ox-ACP didomain in complex with NADP and ethyl glycinate from the lobatamide PKS (Gynuella sunshinyii) | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Francois, R.M.M, Fraley, A.E, Piel, J, Weissman, K.J, Gruez, A. | | 登録日 | 2023-03-09 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Modular Oxime Formation by a trans-AT Polyketide Synthase.
Angew.Chem.Int.Ed.Engl., 62, 2023
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6ZL9
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6UFE
 | | The structure of a potassium selective ion channel at atomic resolution | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Transporter | | 著者 | Langan, P.S, Vandavasi, V.G, Sullivan, B, Afonine, P.V, Weiss, K.L. | | 登録日 | 2019-09-24 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | The structure of a potassium-selective ion channel reveals a hydrophobic gate regulating ion permeation.
Iucrj, 7, 2020
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1GS9
 | | Apolipoprotein E4, 22k domain | | 分子名称: | APOLIPOPROTEIN E | | 著者 | Verderame, J.R, Kantardjieff, K, Segelke, B, Weisgraber, K, Rupp, B. | | 登録日 | 2002-01-02 | | 公開日 | 2003-06-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of the 22K Domain of Human Apolipoprotein E4
To be Published
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6BIT
 | | SIRPalpha antibody complex | | 分子名称: | KWAR23 Fab heavy chain, KWAR23 Fab light chain, Tyrosine-protein phosphatase non-receptor type substrate 1 | | 著者 | Ring, N.G, Herndler-Brandstetter, D, Weiskopf, K, Shan, L, Volkmer, J.P, George, B.M, Lietzenmayer, M, McKenna, K.M, Naik, T.J, McCarty, A, Zheng, Y, Ring, A.M, Flavell, R.A, Weissman, I.L. | | 登録日 | 2017-11-03 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.191 Å) | | 主引用文献 | Anti-SIRP alpha antibody immunotherapy enhances neutrophil and macrophage antitumor activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6B85
 | | Crystal structure of transmembrane protein TMHC4_R | | 分子名称: | TMHC4_R | | 著者 | Lu, P, DiMaio, F, Min, D, Bowie, J, Wei, K.Y, Baker, D. | | 登録日 | 2017-10-05 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.889 Å) | | 主引用文献 | Accurate computational design of multipass transmembrane proteins.
Science, 359, 2018
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6B87
 | | Crystal structure of transmembrane protein TMHC2_E | | 分子名称: | TMHC2_E | | 著者 | Lu, P, DiMaio, F, Min, D, Wei, K.Y, Bowie, J, Baker, D. | | 登録日 | 2017-10-05 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.947 Å) | | 主引用文献 | Accurate computational design of multipass transmembrane proteins.
Science, 359, 2018
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8R6K
 | | Crystal structure of Candida glabrata Bdf1 bromodomain 1 bound to a phenyltriazine ligand | | 分子名称: | 6-methyl-~{N}-[(5-methylfuran-2-yl)methyl]-3-(4-methylphenyl)-1,2,4-triazin-5-amine, Candida glabrata strain CBS138 chromosome C complete sequence, PHOSPHATE ION, ... | | 著者 | Petosa, C, Wei, K, McKenna, C.E, Govin, J. | | 登録日 | 2023-11-22 | | 公開日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection
Advanced Science, 2024
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6ERL
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8R6M
 | | Crystal structure of Candida glabrata Bdf1 bromodomain 2 bound to I-BET151 | | 分子名称: | 7-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-8-METHOXY-1-[(1R)-1-(PYRIDIN-2-YL)ETHYL]-1H,2H,3H-IMIDAZO[4,5-C]QUINOLIN-2-ONE, Candida glabrata strain CBS138 chromosome C complete sequence, GLYCEROL, ... | | 著者 | Petosa, C, Wei, K, McKenna, C.E, Govin, J. | | 登録日 | 2023-11-22 | | 公開日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection
Advanced Science, 2024
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8R6L
 | | Crystal structure of Candida glabrata Bdf1 bromodomain 2 in the unbound state | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Candida glabrata strain CBS138 chromosome C complete sequence, ... | | 著者 | Petosa, C, Wei, K, McKenna, C.E, Govin, J. | | 登録日 | 2023-11-22 | | 公開日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection
Advanced Science, 2024
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8R6I
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8R6J
 | | Crystal structure of Candida glabrata Bdf1 bromodomain 1 bound to a pyrazole ligand | | 分子名称: | 2-methyl-~{N}-[[5-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]methyl]pyrazole-3-carboxamide, Candida glabrata strain CBS138 chromosome C complete sequence, SULFATE ION | | 著者 | Petosa, C, Wei, K, McKenna, C.E, Govin, J. | | 登録日 | 2023-11-22 | | 公開日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection
Advanced Science, 2024
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8R6N
 | | Crystal structure of Candida glabrata Bdf1 bromodomain 2 bound to a pyridoindole ligand | | 分子名称: | 2-ethanoyl-~{N}-(4-morpholin-4-ylphenyl)-1,3,4,5-tetrahydropyrido[4,3-b]indole-8-carboxamide, Candida glabrata strain CBS138 chromosome C complete sequence | | 著者 | Petosa, C, Wei, K, McKenna, C.E, Govin, J. | | 登録日 | 2023-11-22 | | 公開日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection
Advanced Science, 2024
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6U58
 | | Toho1 Beta Lactamase Glu166Gln Mutant | | 分子名称: | Beta-lactamase, SULFATE ION | | 著者 | Langan, P.S, Sullivan, B, Weiss, K.L. | | 登録日 | 2019-08-27 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | NEUTRON DIFFRACTION (1.9 Å), X-RAY DIFFRACTION | | 主引用文献 | Probing the Role of the Conserved Residue Glu166 in a Class A Beta-Lactamase Using Neutron and X-ray Protein Crystallography
Acta Crystallogr.,Sect.D, 76, 2020
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6V8Y
 | | Structure of a Sodium Potassium ion Channel | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein, ... | | 著者 | Roy, R, Weiss, K.L, Coates, L. | | 登録日 | 2019-12-12 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Structural plasticity of the selectivity filter in a nonselective ion channel.
Iucrj, 8, 2021
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7PNE
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6DZ1
 | | Studies of Ion Transport in K+ Channels | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein | | 著者 | Langan, P.S, Vandavasi, V.G, Weiss, K.L, Wagner, A, Duman, R, El Omari, K, Afonine, P.V, Coates, L. | | 登録日 | 2018-07-02 | | 公開日 | 2018-11-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Anomalous X-ray diffraction studies of ion transport in K+channels.
Nat Commun, 9, 2018
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7PNG
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8VJ0
 | | Neutron Structure of Oxidized Trp161Phe MnSOD | | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | | 登録日 | 2024-01-05 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-10-16 | | 実験手法 | NEUTRON DIFFRACTION (2.3 Å) | | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Nat Commun, 15, 2024
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8VJ4
 | | X-ray Counterpart to the Neutron Structure of Peroxide-Soaked Trp161Phe MnSOD | | 分子名称: | HYDROGEN PEROXIDE, MANGANESE (II) ION, Superoxide dismutase [Mn], ... | | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | | 登録日 | 2024-01-05 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Nat Commun, 15, 2024
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7O1H
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8VJ8
 | | X-ray Counterpart to Neutron Structure of Reduced Trp161Phe MnSOD | | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | | 登録日 | 2024-01-05 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Nat Commun, 15, 2024
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8VHW
 | | Neutron Structure of Peroxide-Soaked Trp161Phe MnSOD | | 分子名称: | HYDROGEN PEROXIDE, MANGANESE (II) ION, Superoxide dismutase [Mn], ... | | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Coates, L, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | | 登録日 | 2024-01-02 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-10-16 | | 実験手法 | NEUTRON DIFFRACTION (2.3 Å) | | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Nat Commun, 15, 2024
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