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PDB: 258 results
6VFJ
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BU of 6vfj by Molmil
De novo designed icosahedral nanoparticle I53_dn5
Descriptor: I53_dn5A, I53_dn5B
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2020-01-05
Release date:2020-08-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.35 Å)
Cite:Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFH
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BU of 6vfh by Molmil
De novo designed tetrahedral nanoparticle T33_dn10
Descriptor: T33_dn10A, T33_dn10B
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2020-01-05
Release date:2020-08-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFK
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BU of 6vfk by Molmil
De novo designed tetrahedral nanoparticle T33_dn10 displaying 4 copies of BG505-SOSIP trimer on the surface
Descriptor: BG505-SOSIP-T33_dn10A, T33_dn10B
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2020-01-05
Release date:2020-07-22
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.25 Å)
Cite:Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Plos Pathog., 16, 2020
6VFI
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BU of 6vfi by Molmil
De novo designed octahedral nanoparticle O43_dn18
Descriptor: O43_dn18A, O43_dn18B
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2020-01-05
Release date:2020-08-12
Last modified:2020-08-19
Method:ELECTRON MICROSCOPY (4.54 Å)
Cite:Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFL
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BU of 6vfl by Molmil
BG505-SOSIP model reconstructed by subparticle extraction and refinement from a tetrahedral nanoparticle T33_dn10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIPv5.2(7S) - gp120, ...
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2020-01-05
Release date:2020-07-22
Last modified:2020-08-26
Method:ELECTRON MICROSCOPY (4.14 Å)
Cite:Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Plos Pathog., 16, 2020
6V0R
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BU of 6v0r by Molmil
BG505 SOSIP.664 Trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Nogal, B, Cottrell, C.A, Ward, A.B.
Deposit date:2019-11-19
Release date:2020-04-01
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines.
Cell Rep, 30, 2020
6VO3
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BU of 6vo3 by Molmil
AMC009 SOSIP.v4.2 in complex with PGV04 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC009 SOSIP.v4.2 envelope glycoprotein gp120, ...
Authors:Cottrell, C.A, de Val, N, Ward, A.B.
Deposit date:2020-01-29
Release date:2020-09-23
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (4.25 Å)
Cite:Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers.
J.Virol., 94, 2020
6VO0
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BU of 6vo0 by Molmil
BG505 SOSIP.v5.2 in complex with rabbit Fab 43A2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 43A2 heavy chain, ...
Authors:Nogal, B, Cottrell, C.A, Ward, A.B.
Deposit date:2020-01-29
Release date:2020-07-01
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite.
Sci Adv, 6, 2020
6VKN
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BU of 6vkn by Molmil
BG505 SOSIP.v5.2.N241.N289 in complex with rhesus macaque Fab RM19R
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cottrell, C.A, Ward, A.B.
Deposit date:2020-01-21
Release date:2020-08-12
Last modified:2020-09-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations.
NPJ Vaccines, 5, 2020
6VV5
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BU of 6vv5 by Molmil
Cryo-EM structure of porcine epidemic diarrhea virus (PEDV) spike protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITOLEIC ACID, ...
Authors:Kirchdoerfer, R.N, Ward, A.B.
Deposit date:2020-02-17
Release date:2020-02-26
Last modified:2021-04-14
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure and immune recognition of the porcine epidemic diarrhea virus spike protein.
Structure, 29, 2021
8SW7
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BU of 8sw7 by Molmil
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody FP1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 Boost 2 gp120, BG505 Boost 2 gp41, ...
Authors:Pratap, P.P, Antansijevic, A, Ozorowski, G, Ward, A.B.
Deposit date:2023-05-17
Release date:2023-07-26
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Focusing antibody responses to the fusion peptide in rhesus macaques.
Biorxiv, 2023
8T56
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BU of 8t56 by Molmil
Structure of mechanically activated ion channel OSCA1.2 in peptidiscs
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ...
Authors:Burendei, B, Jojoa-Cruz, S, Lee, W.H, Ward, A.B.
Deposit date:2023-06-12
Release date:2023-12-27
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain.
Structure, 32, 2024
8T57
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BU of 8t57 by Molmil
Structure of mechanically activated ion channel OSCA2.3 in peptidiscs
Descriptor: CHOLESTEROL, CSC1-like protein HYP1, PALMITIC ACID
Authors:Jojoa-Cruz, S, Burendei, B, Lee, W.H, Ward, A.B.
Deposit date:2023-06-12
Release date:2023-12-27
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain.
Structure, 32, 2024
8T4A
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BU of 8t4a by Molmil
MD65 N332-GT5 SOSIP in complex with RM_N332_36 Fab and RM20A3 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MD65 N332-GT5 SOSIP gp120, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2023-06-08
Release date:2024-05-08
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Science, 384, 2024
8T49
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BU of 8t49 by Molmil
MD65 N332-GT5 SOSIP in complex with RM_N332_03 Fab and RM20A3 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MD65 N332-GT5 SOSIP gp120, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2023-06-08
Release date:2024-05-08
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Science, 384, 2024
8SX3
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BU of 8sx3 by Molmil
10E8-GT10.2 immunogen in complex with human Fab 10E8 and mouse Fab W6-10
Descriptor: 10E8 Fab heavy chain, 10E8 light chain, 10E8-GT10.2 immunogen, ...
Authors:Huang, J, Ozorowski, G, Ward, A.B.
Deposit date:2023-05-19
Release date:2024-05-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8T4L
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BU of 8t4l by Molmil
MD65 N332-GT5 SOSIP in complex with RM_N332_07 Fab and RM20A3 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MD65 N332-GT5 SOSIP gp120, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2023-06-09
Release date:2024-05-08
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Science, 384, 2024
8T4K
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BU of 8t4k by Molmil
MD64 N332-GT5 SOSIP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MD64 N332-GT5 SOSIP gp120, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2023-06-09
Release date:2024-05-08
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Science, 384, 2024
8SWX
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BU of 8swx by Molmil
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody Base4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Base4 Heavy Chain, ...
Authors:Pratap, P.P, Antansijevic, A, Ward, A.B.
Deposit date:2023-05-19
Release date:2024-05-22
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Priming antibody responses to the fusion peptide in rhesus macaques.
Npj Vaccines, 9, 2024
8T4D
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BU of 8t4d by Molmil
MD65 N332-GT5 SOSIP in complex with RM_N332_08 Fab and RM20A3 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MD65 N332-GT5 SOSIP gp120, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2023-06-09
Release date:2024-05-08
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Science, 384, 2024
8SWW
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BU of 8sww by Molmil
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody IF3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NHP polyclonal antibody IF3 Heavy Chain, ...
Authors:Pratap, P.P, Antansijevic, A, Ward, A.B.
Deposit date:2023-05-19
Release date:2024-05-22
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Priming antibody responses to the fusion peptide in rhesus macaques.
Npj Vaccines, 9, 2024
8T4B
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BU of 8t4b by Molmil
MD65 N332-GT5 SOSIP in complex with RM_N332_32 Fab and RM20A3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MD65 N332-GT5 SOSIP gp120, MD65 N332-GT5 SOSIP gp41, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2023-06-08
Release date:2024-05-08
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Science, 384, 2024
8T2E
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BU of 8t2e by Molmil
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody FP3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FP3 Heavy Chain, ...
Authors:Pratap, P.P, Antansijevic, A, Ozorowski, G, Ward, A.B.
Deposit date:2023-06-05
Release date:2024-06-12
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Priming antibody responses to the fusion peptide in rhesus macaques.
Npj Vaccines, 9, 2024
8T2F
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BU of 8t2f by Molmil
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody N289
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N289 Heavy Chain, ...
Authors:Pratap, P.P, Antansijevic, A, Ozorowski, G, Ward, A.B.
Deposit date:2023-06-05
Release date:2024-06-12
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Priming antibody responses to the fusion peptide in rhesus macaques.
Npj Vaccines, 9, 2024
8U1C
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BU of 8u1c by Molmil
A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-400 heavy chain, ...
Authors:Ferguson, J.A, Oeverdieck, S, Ward, A.B.
Deposit date:2023-08-31
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface
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226262

数据于2024-10-16公开中

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