5D9Q
 
 | | Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 and scFv NIH45-46 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Julien, J.-P, Stanfield, R.L, Ward, A.B, Wilson, I.A. | | Deposit date: | 2015-08-18 | | Release date: | 2016-08-17 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (4.4 Å) | | Cite: | Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.
Plos Pathog., 12, 2016
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7KEW
 | | Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-43 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BDBV-43 Fab heavy chain, ... | | Authors: | Murin, C.D, Ward, A.B. | | Deposit date: | 2020-10-13 | | Release date: | 2021-04-28 | | Method: | ELECTRON MICROSCOPY (4.16 Å) | | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
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7KFG
 | | Antibody Fab BDBV-289 | | Descriptor: | Antibody Fab BDBV-289 heavy chain, Antibody Fab BDBV-289 light chain, DI(HYDROXYETHYL)ETHER | | Authors: | Murin, C.D, Bruhn, J.F, Ward, A.B. | | Deposit date: | 2020-10-13 | | Release date: | 2021-04-28 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.002 Å) | | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
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7KFE
 | | Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-329 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody BDBV-329 heavy chain, ... | | Authors: | Murin, C.D, Ward, A.B. | | Deposit date: | 2020-10-13 | | Release date: | 2021-04-28 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
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7KFH
 | | Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-437 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab EBOV-437 heavy chain, ... | | Authors: | Murin, C.D, Ward, A.B. | | Deposit date: | 2020-10-13 | | Release date: | 2021-04-28 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
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7KFB
 | | Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-442 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab EBOV-442 heavy chain, ... | | Authors: | Murin, C.D, Ward, A.B. | | Deposit date: | 2020-10-13 | | Release date: | 2021-04-28 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
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7KEX
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7KF9
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7LX3
 | | Cryo-EM structure of EDC-crosslinked ConSOSL.UFO.664 (ConS-EDC) in complex with bNAb PGT122 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Env glycoprotein gp160, ... | | Authors: | Martin, G.M, Ward, A.B, Sattentau, Q.J. | | Deposit date: | 2021-03-03 | | Release date: | 2022-03-09 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens.
Npj Vaccines, 8, 2023
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7LX2
 | | Cryo-EM structure of ConSOSL.UFO.664 (ConS) in complex with bNAb PGT122 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Env glycoprotein gp160, ... | | Authors: | Martin, G.M, Ward, A.B, Sattentau, Q.J. | | Deposit date: | 2021-03-03 | | Release date: | 2022-03-09 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens.
Npj Vaccines, 8, 2023
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7LXM
 | | Cryo-EM structure of ConM SOSIP.v7 (ConM) in complex with bNAb PGT122 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env glycoprotein gp120, ... | | Authors: | Martin, G.M, Ward, A.B, Sattentau, Q.J. | | Deposit date: | 2021-03-04 | | Release date: | 2022-03-09 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens.
Npj Vaccines, 8, 2023
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7LXN
 | | Cryo-EM structure of EDC-crosslinked ConM SOSIP.v7 (ConM-EDC) in complex with bNAb PGT122 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env glycoprotein gp120, ... | | Authors: | Martin, G.M, Ward, A.B, Sattentau, Q.J. | | Deposit date: | 2021-03-04 | | Release date: | 2022-03-09 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (3.85 Å) | | Cite: | Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens.
Npj Vaccines, 8, 2023
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7MDT
 | | BG505 SOSIP.v5.2 in complex with the monoclonal antibody Rh4O9.8 (as Fab fragment) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Rh4O9.8 monoclonal antibody Heavy Chain, ... | | Authors: | Antanasijevic, A, Ozorowski, G, Nogal, B, Ward, A.B. | | Deposit date: | 2021-04-06 | | Release date: | 2022-01-26 | | Last modified: | 2022-02-02 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | From structure to sequence: Antibody discovery using cryoEM.
Sci Adv, 8, 2022
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7LG6
 | | BG505 SOSIP.v5.2 in complex with VRC40.01 and RM19R Fabs | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Cottrell, C.A, Torres, J.L, Wu, N.R, Ward, A.B. | | Deposit date: | 2021-01-19 | | Release date: | 2021-09-15 | | Last modified: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies.
Cell Rep, 37, 2021
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7MEP
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7MDU
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7M8L
 | | EBOV GP bound to rEBOV-442 and rEBOV-515 Fabs | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Virion spike glycoprotein 1, ... | | Authors: | Murin, C.D, Ward, A.B. | | Deposit date: | 2021-03-30 | | Release date: | 2021-11-10 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Pan-ebolavirus protective therapy by two multifunctional human antibodies.
Cell, 184, 2021
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7L8S
 | | BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-4 from animal Rh.33172 (Wk38 time point) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ... | | Authors: | Antanasijevic, A, Sewall, L.M, Ward, A.B. | | Deposit date: | 2020-12-31 | | Release date: | 2021-08-04 | | Last modified: | 2021-08-25 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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7L89
 | | BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-4 from animal Rh.32034 (Wk26 time point) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ... | | Authors: | Antanasijevic, A, Sewall, L.M, Rantalainen, K, Perrett, H.R, Ward, A.B. | | Deposit date: | 2020-12-31 | | Release date: | 2021-08-04 | | Last modified: | 2021-12-01 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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7L8X
 | | BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-4 from animal Rh.33311 (Wk26 time point) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ... | | Authors: | Antanasijevic, A, Sewall, L.M, Yang, Y.R, Ward, A.B. | | Deposit date: | 2021-01-01 | | Release date: | 2021-08-04 | | Last modified: | 2021-08-25 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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7L90
 | | BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-8 from animal Rh.33311 (Wk26 time point) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ... | | Authors: | Antanasijevic, A, Sewall, L.M, Ward, A.B. | | Deposit date: | 2021-01-01 | | Release date: | 2021-08-04 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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7L86
 | | BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-1 from animal Rh.32034 (Wk26 time point) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ... | | Authors: | Antanasijevic, A, Sewall, L.M, Ward, A.B. | | Deposit date: | 2020-12-31 | | Release date: | 2021-08-04 | | Last modified: | 2021-11-24 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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7L87
 | | BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-2 from animal Rh.32034 (Wk26 time point) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ... | | Authors: | Antanasijevic, A, Sewall, L.M, Yang, Y.R, Perrett, H.R, Ward, A.B. | | Deposit date: | 2020-12-31 | | Release date: | 2021-08-04 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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7L8E
 | | BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-1 from animal Rh.33172 (Wk38 time point) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | Authors: | Antanasijevic, A, Sewall, L.M, Ward, A.B. | | Deposit date: | 2020-12-31 | | Release date: | 2021-08-04 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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7L8W
 | | BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-3 from animal Rh.33311 (Wk26 time point) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ... | | Authors: | Antanasijevic, A, Sewall, L.M, Ward, A.B. | | Deposit date: | 2021-01-01 | | Release date: | 2021-08-04 | | Last modified: | 2021-08-25 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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