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PDB: 722 件
6L4R
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BU of 6l4r by Molmil
Crystal structure of Enterovirus D68 RdRp
分子名称: RdRp
著者Wang, M.L, Li, L, Zhang, Y, Chen, Y.P, Su, D.
登録日2019-10-21
公開日2020-06-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.147 Å)
主引用文献Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel.
J.Struct.Biol., 211, 2020
4X1D
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BU of 4x1d by Molmil
Ytterbium-bound human serum transferrin
分子名称: GLYCEROL, MALONATE ION, Serotransferrin, ...
著者Wang, M, Zhang, H, Sun, H.
登録日2014-11-24
公開日2015-04-08
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
4X1B
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Human serum transferrin with ferric ion bound at the C-lobe only
分子名称: FE (III) ION, GLYCEROL, MALONATE ION, ...
著者Wang, M, Zhang, H, Sun, H.
登録日2014-11-24
公開日2015-04-08
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
4QY1
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BU of 4qy1 by Molmil
Structure of H10 from human-infecting H10N8 in complex with avian receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
登録日2014-07-23
公開日2015-01-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
6LKG
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two-component system protein mediate signal transduction
分子名称: 6-O-phosphono-alpha-D-glucopyranose, ABC transporter, solute-binding protein, ...
著者Wang, M, Tao, Y.
登録日2019-12-19
公開日2020-12-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.948 Å)
主引用文献Interface switch mediates signal transmission in a two-component system.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LKK
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Two-component system protein mediate signal transduction
分子名称: 6-O-phosphono-alpha-D-glucopyranose, ABC transporter, solute-binding protein
著者Wang, M, Tao, Y.
登録日2019-12-19
公開日2020-12-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献Interface switch mediates signal transmission in a two-component system.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LKL
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Two-component system protein mediate signal transduction
分子名称: ABC transporter, solute-binding protein, MALONIC ACID
著者Wang, M, Tao, Y.
登録日2019-12-19
公開日2020-12-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.213 Å)
主引用文献Interface switch mediates signal transmission in a two-component system.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LKI
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Two-component system protein mediate signal transduction
分子名称: ABC transporter, solute-binding protein, MALONIC ACID, ...
著者Wang, M, Tao, Y.
登録日2019-12-19
公開日2020-12-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.781 Å)
主引用文献Interface switch mediates signal transmission in a two-component system.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LKJ
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Two-component system protein mediate signal transduction
分子名称: 6-O-phosphono-beta-D-galactopyranose, ABC transporter, solute-binding protein
著者Wang, M, Tao, Y.
登録日2019-12-19
公開日2020-12-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Interface switch mediates signal transmission in a two-component system.
Proc.Natl.Acad.Sci.USA, 117, 2020
3NHG
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BU of 3nhg by Molmil
RB69 DNA Polymerase (S565G/Y567A) Ternary Complex with dTTP Opposite dG
分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ...
著者Wang, M, Wang, J, Konigsberg, W.H.
登録日2010-06-14
公開日2011-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
3NDK
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RB69 DNA Polymerase (Y567A) Ternary Complex with dCTP Opposite dG
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M, Wang, J, Konigsberg, W.H.
登録日2010-06-07
公開日2011-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
3NGI
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BU of 3ngi by Molmil
RB69 DNA Polymerase (Y567A) Ternary Complex with dTTP Opposite dG
分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ...
著者Wang, M, Wang, J, Konigsberg, W.H.
登録日2010-06-11
公開日2011-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.886 Å)
主引用文献Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
6LSE
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BU of 6lse by Molmil
Crystal structure of the enterovirus 71 polymerase elongation complex (C3S6A/C3S6B form)
分子名称: Genome polyprotein, PYROPHOSPHATE 2-, RNA (35-MER), ...
著者Wang, M, Shu, B, Jing, X, Gong, P.
登録日2020-01-17
公開日2020-04-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
6LSF
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BU of 6lsf by Molmil
Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6RA/C2S6RB form)
分子名称: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ...
著者Wang, M, Shu, B, Jing, X, Gong, P.
登録日2020-01-17
公開日2020-04-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.152 Å)
主引用文献Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
3NCI
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BU of 3nci by Molmil
RB69 DNA Polymerase Ternary Complex with dCTP Opposite dG at 1.8 angstrom resolution
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M, Blaha, G, Steitz, T.A, Konigsberg, W.H, Wang, J.
登録日2010-06-04
公開日2011-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Insights into base selectivity from the 1.8 A resolution structure of an RB69 DNA polymerase ternary complex.
Biochemistry, 50, 2011
3LZI
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BU of 3lzi by Molmil
RB69 DNA Polymerase (Y567A) ternary complex with dATP Opposite 7,8-dihydro-8-oxoguanine
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H.
登録日2010-03-01
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .
Biochemistry, 49, 2010
3LZJ
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BU of 3lzj by Molmil
RB69 DNA Polymerase (Y567A) ternary complex with dCTP Opposite 7,8-Dihydro-8-oxoguanine
分子名称: CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H.
登録日2010-03-01
公開日2010-05-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .
Biochemistry, 49, 2010
3NAE
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BU of 3nae by Molmil
RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H.
登録日2010-06-01
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin .
Biochemistry, 49, 2010
3NE6
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BU of 3ne6 by Molmil
RB69 DNA Polymerase (S565G/Y567A) Ternary Complex with dCTP Opposite dG
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M, Wang, J, Konigsberg, W.H.
登録日2010-06-08
公開日2011-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
3S9H
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BU of 3s9h by Molmil
RB69 DNA Polymerase Triple Mutant(L561A/S565G/Y567A) ternary complex with dUpNpp and a dideoxy-terminated primer in the presence of Ca2+
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ...
著者Wang, M, Wang, J, Konigsberg, W.H.
登録日2011-06-01
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
3SJJ
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RB69 DNA Polymerase Triple Mutant (L561A/S565G/Y567A) Ternary Complex with dUpNpp and a Deoxy-terminated Primer in the presence of Mn2+
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ...
著者Wang, M, Wang, J, Konigsberg, W.H.
登録日2011-06-21
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
3SNN
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BU of 3snn by Molmil
RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dCTP Opposite dG in the presence of Mg2+
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3', 5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ...
著者Wang, M, Wang, J, Konigsberg, W.H.
登録日2011-06-29
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
3SCX
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BU of 3scx by Molmil
RB69 DNA Polymerase Triple Mutant(L561A/S565G/Y567A) Ternary Complex with dUpNpp and a Deoxy-terminated Primer in the Presence of Ca2+
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ...
著者Wang, M, Wang, J, Konigsberg, W.H.
登録日2011-06-08
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
6JJP
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Crystal structure of Fab of a PD-1 monoclonal antibody MW11-h317 in complex with PD-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of MW11-h317, Programmed cell death protein 1, ...
著者Wang, M, Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M.
登録日2019-02-26
公開日2019-10-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of a monoclonal antibody that targets PD-1 in a manner requiring PD-1 Asn58 glycosylation.
Commun Biol, 2, 2019
1SIR
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BU of 1sir by Molmil
The Crystal Structure and Mechanism of Human Glutaryl-CoA Dehydrogenase
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Glutaryl-CoA dehydrogenase, S-4-NITROBUTYRYL-COA
著者Wang, M, Fu, Z, Paschke, R, Goodman, S.L, Frerman, F.E, Kim, J.J.
登録日2004-03-01
公開日2004-09-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structures of Human Glutaryl-CoA Dehydrogenase with and without an Alternate Substrate: Structural Bases of Dehydrogenation and Decarboxylation Reactions
Biochemistry, 43, 2004

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