1YD2
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant Y19F bound to the catalytic divalent cation | 分子名称: | GLYCEROL, MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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5WXB
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3TKR
| Crystal structure of full-length human peroxiredoxin 4 with T118E mutation | 分子名称: | Peroxiredoxin-4 | 著者 | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | 登録日 | 2011-08-28 | 公開日 | 2011-10-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
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3TKQ
| Crystal structure of full-length human peroxiredoxin 4 with mixed conformation | 分子名称: | Peroxiredoxin-4 | 著者 | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | 登録日 | 2011-08-28 | 公開日 | 2011-10-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
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6V51
| Spin-labeled T4 Lysozyme (9/131FnbY)-(4-Amino-TEMPO) | 分子名称: | 4-amino-2,2,6,6-tetramethylpiperidin-1-ol, Endolysin | 著者 | Liu, J, Morizumi, T, Ou, W.L, Wang, L, Ernst, O.P. | 登録日 | 2019-12-02 | 公開日 | 2020-10-07 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Genetically Encoded Quinone Methides Enabling Rapid, Site-Specific, and Photocontrolled Protein Modification with Amine Reagents. J.Am.Chem.Soc., 142, 2020
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3TKS
| Crystal structure of full-length human peroxiredoxin 4 in three different redox states | 分子名称: | PEROXIDE ION, Peroxiredoxin-4 | 著者 | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | 登録日 | 2011-08-28 | 公開日 | 2011-10-05 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
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3TKP
| Crystal structure of full-length human peroxiredoxin 4 in the reduced form | 分子名称: | Peroxiredoxin-4 | 著者 | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | 登録日 | 2011-08-28 | 公開日 | 2011-10-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
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3R7W
| Crystal Structure of Gtr1p-Gtr2p complex | 分子名称: | GTP-binding protein GTR1, GTP-binding protein GTR2, MAGNESIUM ION, ... | 著者 | Gong, R, Li, L, Liu, Y, Wang, P, Yang, H, Wang, L, Cheng, J, Guan, K.L, Xu, Y. | 登録日 | 2011-03-23 | 公開日 | 2011-08-24 | 最終更新日 | 2013-06-19 | 実験手法 | X-RAY DIFFRACTION (2.773 Å) | 主引用文献 | Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation Genes Dev., 25, 2011
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8WY4
| GajA tetramer with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-10-30 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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8WY5
| Structure of Gabija GajA in complex with DNA | 分子名称: | CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*T)-3'), ... | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-10-30 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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8X5I
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8X5N
| Tetramer Gabija with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, Gabija protein GajB, ... | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-11-17 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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8X51
| Cryo-EM structure of Gabija GajA in complex with DNA(focused refinement) | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*TP*T)-3'), ... | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-11-16 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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1X70
| HUMAN DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH A BETA AMINO ACID INHIBITOR | 分子名称: | (2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-A MINE, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kim, D, Wang, L, Beconi, M, Eiermann, G.J, Fisher, M.H, He, H, Hickey, G.J, Leiting, B, Lyons, K. | 登録日 | 2004-08-12 | 公開日 | 2005-01-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | (2R)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes J.Med.Chem., 48, 2005
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7WED
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7WLC
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7WEC
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7WE7
| SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv282 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 282, ... | 著者 | Wang, X, Wang, L. | 登録日 | 2021-12-23 | 公開日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants. Nature, 603, 2022
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7WEF
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7WE8
| SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv265 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 265, ... | 著者 | Wang, X, Wang, L. | 登録日 | 2021-12-23 | 公開日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants. Nature, 603, 2022
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7WEE
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7WEA
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7WE9
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7WEB
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3O6Y
| Robust computational design, optimization, and structural characterization of retroaldol enzymes | 分子名称: | Retro-Aldolase, SULFATE ION | 著者 | Althoff, E.A, Wang, L, Jiang, L, Moody, J, Bolduc, J, Lassila, J.K, Wang, Z.Z, Smith, M, Hari, S, Herschlag, D, Stoddard, B.L, Baker, D. | 登録日 | 2010-07-29 | 公開日 | 2011-06-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.091 Å) | 主引用文献 | Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design. J.Mol.Biol., 415, 2012
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