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PDB: 120 results

8UF9
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EcDsbA in complex with 2-benzyl-4-phenylthiazole-5-carboxylic acid
Descriptor: 2-benzyl-4-phenyl-1,3-thiazole-5-carboxylic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA
Authors:Wang, G, Heras, B.
Deposit date:2023-10-04
Release date:2024-10-16
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Two-mode inhibition of DsbA: combination of two site-specific inhibitors enhances virulence inhibition in Salmonella enterica serovar Typhimurium
To Be Published
7TTV
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BU of 7ttv by Molmil
E.coli DsbA in complex with 4-phenyl-2-(3-phenylpropyl)thiazole-5-carboxylic acid
Descriptor: 4-phenyl-2-(3-phenylpropyl)-1,3-thiazole-5-carboxylic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA
Authors:Wang, G, Heras, B.
Deposit date:2022-02-02
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Methyl probes in proteins for determining ligand binding mode in weak protein-ligand complexes.
Sci Rep, 12, 2022
5T17
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BU of 5t17 by Molmil
NMR structure of the E. coli protein NPr, residues 1-85
Descriptor: Phosphocarrier protein NPr
Authors:Wang, G, Li, X, Peterkofsky, A.
Deposit date:2016-08-18
Release date:2016-09-28
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of NPr, a bacterial signal-transducing protein that controls the phosphorylation state of the potassium transporter-regulating protein IIA Ntr.
Amino Acids, 35, 2008
2LMF
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BU of 2lmf by Molmil
Solution structure of human LL-23 bound to membrane-mimetic micelles
Descriptor: Antibacterial protein LL-37
Authors:Wang, G.
Deposit date:2011-11-30
Release date:2011-12-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure, Dynamics, and Antimicrobial and Immune Modulatory Activities of Human LL-23 and Its Single-Residue Variants Mutated on the Basis of Homologous Primate Cathelicidins.
Biochemistry, 51, 2012
2L5M
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BU of 2l5m by Molmil
Solution structure of GF-17 in complex with micelles
Descriptor: GF-17
Authors:Wang, G.
Deposit date:2010-11-02
Release date:2011-11-02
Last modified:2012-02-29
Method:SOLUTION NMR
Cite:Decoding the Functional Roles of Cationic Side Chains of the Major Antimicrobial Region of Human Cathelicidin LL-37.
Antimicrob.Agents Chemother., 56, 2012
6XSP
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BU of 6xsp by Molmil
Crystal structure of E.coli DsbA in complex with 2-(2,6-bis(3-methoxyphenyl)benzofuran-3-yl)acetic acid
Descriptor: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [2,6-bis(3-methoxyphenyl)-1-benzofuran-3-yl]acetic acid
Authors:Wang, G, Heras, B.
Deposit date:2020-07-15
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds.
Bioorg.Med.Chem., 45, 2021
6XSQ
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BU of 6xsq by Molmil
Crystal structure of E.coli DsbA in complex with 2-(6-(3-methoxyphenyl)-2-(4-methoxyphenyl)benzofuran-3-yl)acetic acid
Descriptor: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [6-(3-methoxyphenyl)-2-(4-methoxyphenyl)-1-benzofuran-3-yl]acetic acid
Authors:Wang, G, Heras, B.
Deposit date:2020-07-16
Release date:2021-08-11
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds.
Bioorg.Med.Chem., 45, 2021
6XT3
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BU of 6xt3 by Molmil
Crystal structure of E.coli DsbA in complex with 3-(3-(carboxymethyl)-6-(3-methoxyphenyl)benzofuran-2-yl)benzoic acid
Descriptor: 3-[3-(carboxymethyl)-6-(3-methoxyphenyl)-1-benzofuran-2-yl]benzoic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA
Authors:Wang, G, Heras, B.
Deposit date:2020-07-17
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds.
Bioorg.Med.Chem., 45, 2021
3BGW
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BU of 3bgw by Molmil
The Structure Of A DnaB-Like Replicative Helicase And Its Interactions With Primase
Descriptor: DNAB-Like Replicative Helicase
Authors:Wang, G, Klein, M.G, Tokonzaba, E, Zhang, Y, Holden, L.G, Chen, X.S.
Deposit date:2007-11-27
Release date:2007-12-25
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.91 Å)
Cite:The structure of a DnaB-family replicative helicase and its interactions with primase.
Nat.Struct.Mol.Biol., 15, 2008
1GW3
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BU of 1gw3 by Molmil
THE HELIX-HINGE-HELIX STRUCTURAL MOTIF IN HUMAN APOLIPOPROTEIN A-I DETERMINED BY NMR SPECTROSCOPY, 1 STRUCTURE
Descriptor: APOA-I
Authors:Wang, G, Sparrow, J.T, Cushley, R.J.
Deposit date:1997-06-04
Release date:1997-07-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The helix-hinge-helix structural motif in human apolipoprotein A-I determined by NMR spectroscopy.
Biochemistry, 36, 1997
1GW4
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BU of 1gw4 by Molmil
THE HELIX-HINGE-HELIX STRUCTURAL MOTIF IN HUMAN APOLIPOPROTEIN A-I DETERMINED BY NMR SPECTROSCOPY, 1 STRUCTURE
Descriptor: APOA-I
Authors:Wang, G, Sparrow, J.T, Cushley, R.J.
Deposit date:1997-06-04
Release date:1997-07-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The helix-hinge-helix structural motif in human apolipoprotein A-I determined by NMR spectroscopy.
Biochemistry, 36, 1997
1VM3
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BU of 1vm3 by Molmil
Solution structure of a membrane-targeting peptide designed based on the N-terminal sequence of E. coli enzyme IIA (Glucose)
Descriptor: peptide A3
Authors:Wang, G, Li, X.
Deposit date:2004-08-31
Release date:2004-12-07
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Correlation of Three-dimensional Structures with the Antibacterial Activity of a Group of Peptides Designed Based on a Nontoxic Bacterial Membrane Anchor.
J.Biol.Chem., 280, 2005
1VM2
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BU of 1vm2 by Molmil
Solution structure of an anticancer peptide designed based on the N-terminal sequence of E. coli enzyme IIA (Glucose)
Descriptor: peptide A2
Authors:Wang, G, Li, X.
Deposit date:2004-08-31
Release date:2004-12-07
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Correlation of Three-dimensional Structures with the Antibacterial Activity of a Group of Peptides Designed Based on a Nontoxic Bacterial Membrane Anchor.
J.Biol.Chem., 280, 2005
1VM4
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BU of 1vm4 by Molmil
Solution structure of an antibacterial and antitumor peptide designed based on the N-terminal membrane anchor of E. coli enzyme IIA (Glucose)
Descriptor: peptide A4
Authors:Wang, G, Li, X.
Deposit date:2004-08-31
Release date:2004-12-07
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Correlation of Three-dimensional Structures with the Antibacterial Activity of a Group of Peptides Designed Based on a Nontoxic Bacterial Membrane Anchor.
J.Biol.Chem., 280, 2005
2K6O
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BU of 2k6o by Molmil
Human LL-37 Structure
Descriptor: Cathelicidin antimicrobial peptide
Authors:Wang, G.
Deposit date:2008-07-14
Release date:2008-09-23
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles
J.Biol.Chem., 283, 2008
3KLX
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BU of 3klx by Molmil
Crystal structure of native abscisic acid receptor PYL3
Descriptor: F3N23.20 protein, SULFATE ION
Authors:Zhang, X, Wang, G, Chen, Z.
Deposit date:2009-11-09
Release date:2010-11-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Complex Structures of the Abscisic Acid Receptor PYL3/RCAR13 Reveal a Unique Regulatory Mechanism
Structure, 20, 2012
2Q9Q
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BU of 2q9q by Molmil
The crystal structure of full length human GINS complex
Descriptor: DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, GINS complex subunit 3, ...
Authors:Chang, Y.P, Wang, G, Chen, X.S.
Deposit date:2007-06-13
Release date:2007-08-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Crystal structure of the GINS complex and functional insights into its role in DNA replication.
Proc.Natl.Acad.Sci.Usa, 104, 2007
6LX3
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BU of 6lx3 by Molmil
Cryo-EM structure of human secretory immunoglobulin A
Descriptor: Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor
Authors:Wang, Y, Wang, G, Li, Y, Xiao, J.
Deposit date:2020-02-10
Release date:2020-05-27
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
6LXW
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BU of 6lxw by Molmil
Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA
Descriptor: Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor, ...
Authors:Wang, Y, Wang, G, Li, Y, Xiao, J.
Deposit date:2020-02-12
Release date:2020-05-27
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
1J55
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BU of 1j55 by Molmil
The Crystal Structure of Ca+-bound Human S100P Determined at 2.0A Resolution by X-ray
Descriptor: CALCIUM ION, S-100P PROTEIN
Authors:Zhang, H, Wang, G, Ding, Y, Wang, Z, Barraclough, R, Rudland, P.S, Fernig, D.G, Rao, Z.
Deposit date:2002-01-25
Release date:2003-01-07
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure at 2A Resolution of the Ca2+-binding Protein S100P
J.Mol.Biol., 325, 2003
7XBK
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BU of 7xbk by Molmil
Structure and mechanism of a mitochondrial AAA+ disaggregase CLPB
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Isoform 2 of Caseinolytic peptidase B protein homolog, MAGNESIUM ION, ...
Authors:Wu, D, Liu, Y, Dai, Y, Wang, G, Lu, G, Chen, Y, Li, N, Lin, J, Gao, N.
Deposit date:2022-03-21
Release date:2023-01-25
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Comprehensive structural characterization of the human AAA+ disaggregase CLPB in the apo- and substrate-bound states reveals a unique mode of action driven by oligomerization.
Plos Biol., 21, 2023
7BYR
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BU of 7byr by Molmil
BD23-Fab in complex with the S ectodomain trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab23-Fab-Heavy Chain, ...
Authors:Zhu, Q, Wang, G, Xiao, J.
Deposit date:2020-04-24
Release date:2020-06-10
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells.
Cell, 182, 2020
3KL1
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BU of 3kl1 by Molmil
Crystal structure of abscisic acid receptor PYL2 at 1.55 A
Descriptor: Putative uncharacterized protein At2g26040
Authors:Zhang, X, Wang, G, Chen, Z.
Deposit date:2009-11-06
Release date:2010-11-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Complex Structures of the Abscisic Acid Receptor PYL3/RCAR13 Reveal a Unique Regulatory Mechanism
Structure, 20, 2012
8F28
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BU of 8f28 by Molmil
Lysozyme Structures from Single-Entity Crystallization Method NanoAC
Descriptor: ACETATE ION, CHLORIDE ION, Lysozyme C, ...
Authors:Yang, R, Sankaran, B, Ogbonna, E, Wang, G.
Deposit date:2022-11-07
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:A Single-Entity Method for Actively Controlled Nucleation and High-Quality Protein Crystal Synthesis.
Anal.Chem., 95, 2023
1VE7
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BU of 1ve7 by Molmil
Crystal structure of an acylpeptide hydrolase/esterase from Aeropyrum pernix K1 in complex with p-nitrophenyl phosphate
Descriptor: 4-NITROPHENYL PHOSPHATE, Acylamino-acid-releasing enzyme, GLYCEROL
Authors:Bartlam, M, Wang, G, Gao, R, Yang, H, Zhao, X, Xie, G, Cao, S, Feng, Y, Rao, Z.
Deposit date:2004-03-27
Release date:2004-11-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of an acylpeptide hydrolase/esterase from Aeropyrum pernix K1
STRUCTURE, 12, 2004

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