5WJT
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5XSI
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![BU of 5xsi by Molmil](/molmil-images/mine/5xsi) | The catalytic domain of GdpP | Descriptor: | MANGANESE (II) ION, Phosphodiesterase acting on cyclic dinucleotides | Authors: | Wang, F, Gu, L. | Deposit date: | 2017-06-14 | Release date: | 2018-01-31 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase Biochem. J., 475, 2018
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5WK5
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5WJX
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![BU of 5wjx by Molmil](/molmil-images/mine/5wjx) | Cryo-EM structure of B. subtilis flagellar filaments S17P | Descriptor: | Flagellin | Authors: | Wang, F, Burrage, A.M, Orlova, A, Kearns, D.B, Egelman, E.H. | Deposit date: | 2017-07-24 | Release date: | 2017-10-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
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5WJW
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![BU of 5wjw by Molmil](/molmil-images/mine/5wjw) | Cryo-EM structure of B. subtilis flagellar filaments H84R | Descriptor: | Flagellin | Authors: | Wang, F, Burrage, A.M, Orlova, A, Kearns, D.B, Egelman, E.H. | Deposit date: | 2017-07-24 | Release date: | 2017-10-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
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5WJV
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5WJZ
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![BU of 5wjz by Molmil](/molmil-images/mine/5wjz) | Cryo-EM structure of B. subtilis flagellar filaments E115G | Descriptor: | Flagellin | Authors: | Wang, F, Burrage, A.M, Orlova, A, Kearns, D.B, Egelman, E.H. | Deposit date: | 2017-07-24 | Release date: | 2017-10-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (5.7 Å) | Cite: | A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
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5XSN
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![BU of 5xsn by Molmil](/molmil-images/mine/5xsn) | The catalytic domain of GdpP with c-di-AMP | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MANGANESE (II) ION, Phosphodiesterase acting on cyclic dinucleotides | Authors: | Wang, F, Gu, L. | Deposit date: | 2017-06-14 | Release date: | 2018-01-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase Biochem. J., 475, 2018
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5XBW
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![BU of 5xbw by Molmil](/molmil-images/mine/5xbw) | The structure of BrlR | Descriptor: | Probable transcriptional regulator | Authors: | Wang, F, Qing, H, Gu, L. | Deposit date: | 2017-03-21 | Release date: | 2018-05-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.109 Å) | Cite: | BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin. Nat Commun, 9, 2018
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5XBI
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5XBT
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![BU of 5xbt by Molmil](/molmil-images/mine/5xbt) | The structure of BrlR bound to c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Wang, F, Qing, H, Gu, L. | Deposit date: | 2017-03-21 | Release date: | 2018-05-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.495 Å) | Cite: | BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin. Nat Commun, 9, 2018
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2I46
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![BU of 2i46 by Molmil](/molmil-images/mine/2i46) | Crystal structure of human TPP1 | Descriptor: | Adrenocortical dysplasia protein homolog | Authors: | Wang, F, Podell, E.R, Zaug, A.J, Yang, Y.T, Baciu, P, Else, T, Hammer, G.D, Cech, T.R, Lei, M. | Deposit date: | 2006-08-21 | Release date: | 2006-11-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature, 445, 2007
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2HVC
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![BU of 2hvc by Molmil](/molmil-images/mine/2hvc) | The Crystal Structure of Ligand-binding Domain (LBD) of human Androgen Receptor in Complex with a selective modulator LGD2226 | Descriptor: | 6-[BIS(2,2,2-TRIFLUOROETHYL)AMINO]-4-(TRIFLUOROMETHYL)QUINOLIN-2(1H)-ONE, Androgen receptor | Authors: | Wang, F, Liu, X.-Q, Li, H, Liang, K.-N, Miner, J.N, Hong, M, Kallel, E.A, van Oeveren, A, Zhi, L, Jiang, T. | Deposit date: | 2006-07-28 | Release date: | 2007-07-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the ligand-binding domain (LBD) of human androgen receptor in complex with a selective modulator LGD2226 ACTA CRYSTALLOGR.,SECT.F, 62, 2006
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2H9I
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![BU of 2h9i by Molmil](/molmil-images/mine/2h9i) | Mycobacterium tuberculosis InhA bound with ETH-NAD adduct | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH], {(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-ETHYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}METHYL [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE | Authors: | Wang, F, Sacchettini, J.C. | Deposit date: | 2006-06-09 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mechanism of thioamide drug action against tuberculosis and leprosy. J.Exp.Med., 204, 2007
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2LQI
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![BU of 2lqi by Molmil](/molmil-images/mine/2lqi) | NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2l3b conformation) | Descriptor: | CREB-binding protein, Forkhead box O3 | Authors: | Wang, F, Marshall, C.B, Yamamoto, K, Li, G.B, Gasmi-Seabrook, G.M.C, Okada, H, Mak, T.W, Ikura, M. | Deposit date: | 2012-03-06 | Release date: | 2012-05-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment. Proc.Natl.Acad.Sci.USA, 109, 2012
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2LQH
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![BU of 2lqh by Molmil](/molmil-images/mine/2lqh) | NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2b3l conformation) | Descriptor: | CREB-binding protein, Forkhead box O3 | Authors: | Wang, F, Marshall, C.B, Yamamoto, K, Li, G.B, Gasmi-Seabrook, G.M.C, Okada, H, Mak, T.W, Ikura, M. | Deposit date: | 2012-03-06 | Release date: | 2012-05-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment. Proc.Natl.Acad.Sci.USA, 109, 2012
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7ESE
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![BU of 7ese by Molmil](/molmil-images/mine/7ese) | The Crystal Structure of human DHFR from Biortus | Descriptor: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Wang, F, Cheng, W, Xu, C, Qi, J, Bao, X, Miao, Q. | Deposit date: | 2021-05-10 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Crystal Structure of human DHFR from Biortus To Be Published
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6XG6
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![BU of 6xg6 by Molmil](/molmil-images/mine/6xg6) | Full-length human mitochondrial Hsp90 (TRAP1) with ADP-BeF3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Heat shock protein 75 kDa, ... | Authors: | Liu, Y.X, Wang, F, Agard, D.A. | Deposit date: | 2020-06-17 | Release date: | 2020-09-30 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | General and robust covalently linked graphene oxide affinity grids for high-resolution cryo-EM. Proc.Natl.Acad.Sci.USA, 117, 2020
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6DY7
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![BU of 6dy7 by Molmil](/molmil-images/mine/6dy7) | WDR5 in complex with a WIN site inhibitor | Descriptor: | DIMETHYL SULFOXIDE, N-[3-(2,4-dichlorophenoxy)propyl]-1H-imidazol-2-amine, SULFATE ION, ... | Authors: | Phan, J, Wang, F, Fesik, S.W. | Deposit date: | 2018-07-01 | Release date: | 2019-03-13 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Rep, 26, 2019
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6DYA
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![BU of 6dya by Molmil](/molmil-images/mine/6dya) | WDR5 in complex with a WIN site inhibitor | Descriptor: | DIMETHYL SULFOXIDE, N-[(3,5-dichlorophenyl)methyl]-3-[(1H-imidazol-1-yl)methyl]benzamide, SULFATE ION, ... | Authors: | Phan, J, Wang, F, Fesik, S.W. | Deposit date: | 2018-07-01 | Release date: | 2019-03-13 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Rep, 26, 2019
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3MAQ
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![BU of 3maq by Molmil](/molmil-images/mine/3maq) | Crystal structure of E.coli Pol II-normal DNA-dGTP ternary complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*CP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... | Authors: | Yang, W, Wang, F. | Deposit date: | 2010-03-24 | Release date: | 2010-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
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4ZWV
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![BU of 4zwv by Molmil](/molmil-images/mine/4zwv) | Crystal Structure of Aminotransferase AtmS13 from Actinomadura melliaura | Descriptor: | GLYCEROL, Putative aminotransferase | Authors: | Kim, Y, Bigelow, L, Endres, M, Wang, F, Phillips Jr, G.N, Joachimiak, A, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-05-19 | Release date: | 2015-06-03 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (1.503 Å) | Cite: | Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis. Proteins, 83, 2015
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7SLZ
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![BU of 7slz by Molmil](/molmil-images/mine/7slz) | CRYSTAL STRUCTURE OF GID4 IN COMPLEX WITH BPF023596 | Descriptor: | Glucose-induced degradation protein 4 homolog, N-[(1s,4s)-4-(1H-benzimidazol-2-yl)cyclohexyl]-N~2~-[(1H-indol-2-yl)methyl]glycinamide | Authors: | Song, X, Dong, A, Calabrese, M, Wang, F, Owen, D, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2021-10-25 | Release date: | 2022-01-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | CRYSTAL STRUCTURE OF GID4 IN COMPLEX WITH BPF023596 To Be Published
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5W5F
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![BU of 5w5f by Molmil](/molmil-images/mine/5w5f) | Cryo-EM structure of the T4 tail tube | Descriptor: | Tail tube protein gp19 | Authors: | Zheng, W, Wang, F, Taylor, N.M, Guerrero-Ferreira, R.C, Leiman, P.G, Egelman, E.H. | Deposit date: | 2017-06-15 | Release date: | 2017-08-16 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Refined Cryo-EM Structure of the T4 Tail Tube: Exploring the Lowest Dose Limit. Structure, 25, 2017
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7DLV
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![BU of 7dlv by Molmil](/molmil-images/mine/7dlv) | shrimp dUTPase in complex with Stl | Descriptor: | CALCIUM ION, Orf20, SULFATE ION, ... | Authors: | Ma, Q, Wang, F. | Deposit date: | 2020-11-30 | Release date: | 2021-12-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.525 Å) | Cite: | Structural basis of staphylococcal Stl inhibition on a eukaryotic dUTPase. Int.J.Biol.Macromol., 184, 2021
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