5XZA
 
 | | Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent 6-phosphofructokinase, CITRATE ANION, ... | | Authors: | Wang, C.L, Tian, T, Zang, J.Y. | | Deposit date: | 2017-07-12 | | Release date: | 2019-03-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion.
Biochemistry, 57, 2018
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7CJX
 | | UDP-glucuronosyltransferase 2B15 C-terminal domain-L446S | | Descriptor: | L(+)-TARTARIC ACID, UDP-glucuronosyltransferase 2B15 | | Authors: | Wang, C.Y, Zhang, L. | | Deposit date: | 2020-07-14 | | Release date: | 2021-07-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.986414 Å) | | Cite: | Structure of UDP-glucuronosyltransferase 2B15 C-terminal domain L446S at 1.99 Angstroms resolution
To Be Published
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7DLA
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7D4B
 | | Crystal structure of 4-1BB in complex with a VHH | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | Authors: | Wang, C. | | Deposit date: | 2020-09-23 | | Release date: | 2021-07-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.14 Å) | | Cite: | Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer.
J Immunother Cancer, 9, 2021
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5XZ7
 | | Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with adenylylimidodiphosphate, the ATP analogue | | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, ATP-dependent 6-phosphofructokinase, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Wang, C.L, Tian, T, Zang, J.Y. | | Deposit date: | 2017-07-11 | | Release date: | 2019-03-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion.
Biochemistry, 57, 2018
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5XZ8
 | | Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with adenylylimidodiphosphate (the ATP analog) and fructose-6-phosphate | | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, ATP-dependent 6-phosphofructokinase, GLYCEROL, ... | | Authors: | Wang, C.L, Tian, T, Zang, J.Y. | | Deposit date: | 2017-07-11 | | Release date: | 2019-02-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion.
Biochemistry, 57, 2018
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5XZ6
 | | Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with adenylylimidodiphosphate, the ATP analogue | | Descriptor: | ATP-dependent 6-phosphofructokinase, GLYCEROL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Wang, C.L, Tian, T, Zang, J.Y. | | Deposit date: | 2017-07-11 | | Release date: | 2019-02-27 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion.
Biochemistry, 57, 2018
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7WN1
 | | Structure of PfNT1(Y190A) in complex with nanobody 48 and inosine | | Descriptor: | Equilibrative nucleoside/nucleobase transporter, INOSINE, nanobody48 | | Authors: | Wang, C, Deng, D, Ren, R.B, Yu, L.Y. | | Deposit date: | 2022-01-17 | | Release date: | 2023-02-01 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Nat Commun, 14, 2023
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7XDG
 | | Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor MDSA | | Descriptor: | 5-[(3-carboxy-4-oxidanyl-phenyl)methyl]-2-oxidanyl-benzoic acid, NAD-dependent malic enzyme, mitochondrial, ... | | Authors: | Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C. | | Deposit date: | 2022-03-27 | | Release date: | 2023-03-29 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Commun Biol, 6, 2023
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7XDF
 | | Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor EA | | Descriptor: | 4-[(3-carboxy-2-oxidanyl-naphthalen-1-yl)methyl]-3-oxidanyl-naphthalene-2-carboxylic acid, NAD-dependent malic enzyme, mitochondrial, ... | | Authors: | Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C. | | Deposit date: | 2022-03-27 | | Release date: | 2023-03-29 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Commun Biol, 6, 2023
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7XDE
 | | Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in apo form | | Descriptor: | NAD-dependent malic enzyme, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C. | | Deposit date: | 2022-03-26 | | Release date: | 2023-03-29 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Commun Biol, 6, 2023
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7YAN
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7UFJ
 | | Structure of human MR1-ethylvanillin in complex with human MAIT A-F7 TCR | | Descriptor: | 3-ethoxy-4-hydroxybenzaldehyde, ACETATE ION, Beta-2-microglobulin, ... | | Authors: | Wang, C.J, Rossjohn, J, Le Nours, J. | | Deposit date: | 2022-03-22 | | Release date: | 2022-12-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Quantitative affinity measurement of small molecule ligand binding to Major Histocompatibility Complex class-I related protein 1 MR1.
J.Biol.Chem., 298, 2022
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6LPW
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7C4J
 | | Cryo-EM structure of the yeast Swi/Snf complex in a nucleosome free state | | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Regulator of Ty1 transposition protein 102, ... | | Authors: | Wang, C.C, Guo, Z.Y, Zhan, X.C, Zhang, X.F. | | Deposit date: | 2020-05-18 | | Release date: | 2020-07-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Structure of the yeast Swi/Snf complex in a nucleosome free state
Nat Commun, 2020
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5XOE
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6KOL
 | | Crystal structure of auracyanin from photosynthetic bacterium Roseiflexus castenholzii | | Descriptor: | Blue (Type 1) copper domain protein, CHLORIDE ION, COPPER (II) ION | | Authors: | Wang, C, Zhang, C.Y, Min, Z.Z, Xin, Y.Y, Xu, X.L. | | Deposit date: | 2019-08-12 | | Release date: | 2020-01-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.211 Å) | | Cite: | Structural basis underlying the electron transfer features of a blue copper protein auracyanin from the photosynthetic bacterium Roseiflexus castenholzii.
Photosyn. Res., 143, 2020
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6L9S
 | | Crystal structure of Na-dithionite reduced auracyanin from photosynthetic bacterium Roseiflexus castenholzii | | Descriptor: | Blue (Type 1) copper domain protein, COPPER (I) ION | | Authors: | Wang, C, Zhang, C.Y, Min, Z.Z, Xu, X.L. | | Deposit date: | 2019-11-10 | | Release date: | 2020-01-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis underlying the electron transfer features of a blue copper protein auracyanin from the photosynthetic bacterium Roseiflexus castenholzii.
Photosyn. Res., 143, 2020
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6LPV
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2LGK
 | | NMR Structure of UHRF1 PHD domains in a complex with histone H3 peptide | | Descriptor: | E3 ubiquitin-protein ligase UHRF1, ZINC ION, histone H3 peptide | | Authors: | Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C. | | Deposit date: | 2011-07-28 | | Release date: | 2011-09-28 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
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2LGG
 | | Structure of PHD domain of UHRF1 in complex with H3 peptide | | Descriptor: | E3 ubiquitin-protein ligase UHRF1, ZINC ION, histone H3 peptide | | Authors: | Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C. | | Deposit date: | 2011-07-26 | | Release date: | 2011-09-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
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2LGL
 | | NMR structure of the UHRF1 PHD domain | | Descriptor: | E3 ubiquitin-protein ligase UHRF1, ZINC ION | | Authors: | Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C. | | Deposit date: | 2011-07-28 | | Release date: | 2011-09-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
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2KCG
 | | Solution structure of cycloviolacin O2 | | Descriptor: | Cycloviolacin-O2 | | Authors: | Wang, C.K. | | Deposit date: | 2008-12-22 | | Release date: | 2009-07-21 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes.
Biophys.J., 97, 2009
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7WN0
 | | Structure of PfENT1(Y190A) in complex with nanobody 19 | | Descriptor: | Equilibrative nucleoside/nucleobase transporter, nanobody19 | | Authors: | Wang, C, Deng, D, Ren, R.B, Yu, L.Y. | | Deposit date: | 2022-01-17 | | Release date: | 2023-02-01 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.64 Å) | | Cite: | Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Nat Commun, 14, 2023
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2KCH
 | | Solution structure of micelle-bound kalata B2 | | Descriptor: | Kalata-B2 | | Authors: | Wang, C.K. | | Deposit date: | 2008-12-21 | | Release date: | 2009-07-21 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes.
Biophys.J., 97, 2009
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