7WO1
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7ENR
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7ENI
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7ENH
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7ENM
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7CNM
| YDX in complex with tubulin | 分子名称: | (2~{S},4~{S})-4-[[2-[(1~{R},3~{R})-1-acetyloxy-4-methyl-3-[[(2~{S},3~{S})-3-methyl-2-[[(2~{R})-1-methylpiperidin-2-yl]carbonylamino]pentanoyl]amino]pentyl]-1,3-thiazol-4-yl]carbonylamino]-5-cyclohexyl-2-methyl-pentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Wang, Y.X, Wu, C.Y. | 登録日 | 2020-08-02 | 公開日 | 2021-08-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | The high-resolution X-ray structure of vinca-domain inhibitors of microtubules provides a rational approach for drug design. Febs Lett., 595, 2021
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2IVH
| Crystal structure of the nuclease domain of ColE7 (H545Q mutant) in complex with an 18-bp duplex DNA | 分子名称: | 5'-D(*GP*GP*AP*AP*TP*TP*CP*GP*AP*TP *CP*GP*AP*AP*TP*TP*CP*C)-3', COLCIN-E7, ZINC ION | 著者 | Wang, Y.T, Yang, W.J, Li, C.L, Doudeva, L.G, Yuan, H.S. | 登録日 | 2006-06-13 | 公開日 | 2007-01-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases. Nucleic Acids Res., 35, 2007
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7DMZ
| GMPCPP microtubule complex | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | 著者 | Wang, Y.X. | 登録日 | 2020-12-08 | 公開日 | 2021-12-08 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | GMPCPP microtubule complex To Be Published
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7DN0
| AJ-GMPCPP-MT-non-seam | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | 著者 | Wang, Y.X. | 登録日 | 2020-12-08 | 公開日 | 2021-12-08 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | GMPCPP microtubule To Be Published
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7Y3E
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2IVK
| Crystal structure of the periplasmic endonuclease Vvn complexed with a 16-bp DNA | 分子名称: | 5'-D(*AP*AP*TP*TP*CP*GP*AP*TP*CP*GP *AP*AP*TP*TP*C)-3', 5'-D(*GP*AP*AP*TP*TP*CP*GP*AP*TP*CP *GP*AP*AP*TP*T)-3', 5'-D(*GP*AP*AP*TP*TP*CP*GP*AP*TP*CP *GP*AP*AP*TP*TP*C)-3', ... | 著者 | Wang, Y.T, Yang, W.J, Li, C.L, Doudeva, L.G, Yuan, H.S. | 登録日 | 2006-06-14 | 公開日 | 2007-01-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases. Nucleic Acids Res., 35, 2007
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2IL3
| Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity | 分子名称: | Epsilon-class Glutathione S-transferase | 著者 | Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L. | 登録日 | 2006-10-02 | 公開日 | 2007-10-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity J.Struct.Biol., 164, 2008
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2IMK
| Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity | 分子名称: | Epsilon-class Glutathione S-transferase, S-HEXYLGLUTATHIONE | 著者 | Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L. | 登録日 | 2006-10-02 | 公開日 | 2007-10-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity J.Struct.Biol., 164, 2008
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2JOW
| Differences in the electrostatic surfaces of the type III secretion needle proteins | 分子名称: | Protein prgI | 著者 | Wang, Y, Ouellette, A.N, Egan, C.W, De Guzman, R.N. | 登録日 | 2007-04-06 | 公開日 | 2007-07-24 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Differences in the Electrostatic Surfaces of the Type III Secretion Needle Proteins PrgI, BsaL, and MxiH J.Mol.Biol., 371, 2007
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2K48
| NMR Structure of the N-terminal Coiled Coil Domain of the Andes Hantavirus Nucleocapsid Protein | 分子名称: | Nucleoprotein | 著者 | Wang, Y, Boudreaux, D.M, Estrada, D.F, Egan, C.W, St Jeor, S.C, De Guzman, R.N. | 登録日 | 2008-05-30 | 公開日 | 2008-08-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of the N-terminal Coiled Coil Domain of the Andes Hantavirus Nucleocapsid Protein. J.Biol.Chem., 283, 2008
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7WO3
| SARS-CoV-2 3CLpro | 分子名称: | (2S)-2-[[(2S)-2-[[(E)-3-(4-methoxyphenyl)prop-2-enoyl]amino]-3-methyl-butanoyl]amino]-4-methyl-N-[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepiperidin-3-yl]propan-2-yl]pentanamide, 3C-like proteinase | 著者 | Wang, Y, Ye, S. | 登録日 | 2022-01-20 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions. Int J Mol Sci, 23, 2022
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2M5I
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7WO2
| SARS-CoV-2 3CLPro Peptidomimetic Inhibitor TPM5 | 分子名称: | 3C-like proteinase, N-[(2S)-3-methyl-1-[[(2S)-4-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanylidene-3-[(3S}-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]furan-2-carboxamide | 著者 | Wang, Y, Ye, S. | 登録日 | 2022-01-20 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions. Int J Mol Sci, 23, 2022
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2KKT
| Solution structure of the SCA7 domain of human Ataxin-7-L3 protein | 分子名称: | Ataxin-7-like protein 3, ZINC ION | 著者 | Wang, Y, Atkinson, A.R, Bonnet, J, Romier, C, Kieffer, B. | 登録日 | 2009-06-29 | 公開日 | 2010-06-16 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Histone deubiquitination by SAGA is modulated by an atypical zinc finger domain of Ataxin-7 To be Published
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7WQB
| SARS-CoV-2 main protease mutant (P168A) in complex with MG-132 | 分子名称: | 3C-like proteinase nsp5, MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]-L-leucinamide | 著者 | Wang, Y.C, Yang, C.S, Hou, M.H, Tsai, C.L, Chen, Y. | 登録日 | 2022-01-25 | 公開日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | SARS-CoV-2 main protease mutant (P168A) in complex with MG-132 To Be Published
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7CNN
| vinorelbine in complex with tubulin | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wang, Y.X, Wu, C.Y. | 登録日 | 2020-08-02 | 公開日 | 2021-08-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The high-resolution X-ray structure of vinca-domain inhibitors of microtubules provides a rational approach for drug design. Febs Lett., 595, 2021
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4N74
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7WOH
| SARS-CoV-2 3CLpro | 分子名称: | (2S)-4-methyl-N-[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-2-[[(2S)-3-phenyl-2-[[(E)-3-phenylprop-2-enoyl]amino]propanoyl]amino]pentanamide, 3C-like proteinase | 著者 | Wang, Y, Ye, S. | 登録日 | 2022-01-21 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions. Int J Mol Sci, 23, 2022
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7WQA
| SARS-CoV-2 main protease in complex with Z-VAD-FMK | 分子名称: | 3C-like proteinase, Z-VAD(OMe)-FMK | 著者 | Wang, Y.C, Yang, C.S, Hou, M.H, Tsai, C.L, Chen, Y. | 登録日 | 2022-01-25 | 公開日 | 2023-03-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | SARS-CoV-2 main protease in complex with Z-VAD-FMK To Be Published
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7WQ9
| Crystal structure of SARS-CoV-2 main protease in complex with Z-IETD-FMK | 分子名称: | 3C-like proteinase, Z-IETD-FMK | 著者 | Wang, Y.C, Yang, C.S, Hou, M.H, Tsai, C.L, Chen, Y. | 登録日 | 2022-01-25 | 公開日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.054 Å) | 主引用文献 | Crystal structure of SARS-CoV-2 main protease in complex with Z-IETD-FMK To Be Published
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