7H1C
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![BU of 7h1c by Molmil](/molmil-images/mine/7h1c) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0014597-001 | 分子名称: | 7-[(1S)-1-{[(5R,8S)-10-acetyl-6,7,8,9-tetrahydro-5H-5,8-epiminocyclohepta[d]pyrimidin-4-yl]amino}-2-methylpropyl]-3,4-dihydro-1lambda~6~-benzothiopyran-1,1(2H)-dione, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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7H08
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![BU of 7h08 by Molmil](/molmil-images/mine/7h08) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0012346-001 | 分子名称: | 4-{[(1S)-1-(1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~-benzothiopyran-7-yl)-2-methylpropyl]amino}-N-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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7H13
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![BU of 7h13 by Molmil](/molmil-images/mine/7h13) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0013385-001 | 分子名称: | 7-[(1R)-1-{[(6M)-6-(3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}-2-methylpropyl]-3,4-dihydro-1lambda~6~-benzothiopyran-1,1(2H)-dione, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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6KWL
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![BU of 6kwl by Molmil](/molmil-images/mine/6kwl) | Crystal structure of pSLA-1*0401(R156A) complex with FMDV-derived epitope MTAHITVPY | 分子名称: | Beta-2-microglobulin, MHC class I antigen, peptide | 著者 | Wei, X.H, Wang, S, Zhang, N.Z, Xia, C. | 登録日 | 2019-09-07 | 公開日 | 2020-09-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Peptidomes and Structures Illustrate Two Distinguishing Mechanisms of Alternating the Peptide Plasticity Caused by Swine MHC Class I Micropolymorphism. Front Immunol, 12, 2021
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6KWO
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![BU of 6kwo by Molmil](/molmil-images/mine/6kwo) | Crystal structure of pSLA-1*1301 complex with mutant epitope ESDTVGWSW | 分子名称: | Beta-2-microglobulin, MHC class I antigen, peptide | 著者 | Wei, X.H, Wang, S, Zhang, N.Z, Xia, C. | 登録日 | 2019-09-07 | 公開日 | 2020-09-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | Peptidomes and Structures Illustrate Two Distinguishing Mechanisms of Alternating the Peptide Plasticity Caused by Swine MHC Class I Micropolymorphism. Front Immunol, 12, 2021
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1JPX
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![BU of 1jpx by Molmil](/molmil-images/mine/1jpx) | Mutation that destabilize the gp41 core: determinants for stabilizing the SIV/CPmac envelope glycoprotein complex. Wild type. | 分子名称: | gp41 envelope protein | 著者 | Liu, J, Wang, S, LaBranche, C.C, Hoxie, J.A, Lu, M. | 登録日 | 2001-08-03 | 公開日 | 2002-04-24 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mutations that destabilize the gp41 core are determinants for stabilizing the simian immunodeficiency virus-CPmac envelope glycoprotein complex. J.Biol.Chem., 277, 2002
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1JQ0
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![BU of 1jq0 by Molmil](/molmil-images/mine/1jq0) | Mutation that destabilize the gp41 core: determinants for stabilizing the SIV/CPmac envelope glycoprotein complex. Mutant structure. | 分子名称: | gp41 envelope protein | 著者 | Liu, J, Wang, S, LaBranche, C.C, Hoxie, J.A, Lu, M. | 登録日 | 2001-08-03 | 公開日 | 2002-04-24 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mutations that destabilize the gp41 core are determinants for stabilizing the simian immunodeficiency virus-CPmac envelope glycoprotein complex. J.Biol.Chem., 277, 2002
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5H3O
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![BU of 5h3o by Molmil](/molmil-images/mine/5h3o) | Structure of a eukaryotic cyclic nucleotide-gated channel | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel, SODIUM ION | 著者 | Li, M, Zhou, X, Wang, S, Michailidis, I, Gong, Y, Su, D, Li, H, Li, X, Yang, J. | 登録日 | 2016-10-26 | 公開日 | 2017-01-25 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of a eukaryotic cyclic-nucleotide-gated channel. Nature, 542, 2017
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5GYJ
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![BU of 5gyj by Molmil](/molmil-images/mine/5gyj) | Structure of catalytically active sortase from Clostridium difficile | 分子名称: | Putative peptidase C60B, sortase B | 著者 | Yin, J.-C, Fei, C.-H, Hsiao, Y.-Y, Nix, J.C, Huang, I.-H, Wang, S. | 登録日 | 2016-09-22 | 公開日 | 2017-01-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | Structural Insights into Substrate Recognition by Clostridium difficile Sortase. Front Cell Infect Microbiol, 6, 2016
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4ZX5
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![BU of 4zx5 by Molmil](/molmil-images/mine/4zx5) | |
3FZV
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![BU of 3fzv by Molmil](/molmil-images/mine/3fzv) | Crystal structure of PA01 protein, putative LysR family transcriptional regulator from Pseudomonas aeruginosa | 分子名称: | Probable transcriptional regulator, SULFATE ION | 著者 | Knapik, A.A, Tkaczuk, K.L, Chruszcz, M, Wang, S, Zimmerman, M.D, Cymborowski, M, Skarina, T, Kagan, O, Savchenko, A, Edwards, A.M, Joachimiak, A, Bujnicki, J.M, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2009-01-26 | 公開日 | 2009-03-10 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Crystal structure of PA01 protein, putative LysR family transcriptional regulator from Pseudomonas aeruginosa To be Published
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4ZY1
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4U3H
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![BU of 4u3h by Molmil](/molmil-images/mine/4u3h) | |
4ZY2
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![BU of 4zy2 by Molmil](/molmil-images/mine/4zy2) | X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10o | 分子名称: | CARBONATE ION, DIMETHYL SULFOXIDE, N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluorobiphenyl-4-yl)ethyl]-2,2-dimethylpropanamide, ... | 著者 | Drinkwater, N, McGowan, S. | 登録日 | 2015-05-21 | 公開日 | 2016-03-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
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4ZY0
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4ZX9
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![BU of 4zx9 by Molmil](/molmil-images/mine/4zx9) | |
4ZX8
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![BU of 4zx8 by Molmil](/molmil-images/mine/4zx8) | |
4ZYQ
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![BU of 4zyq by Molmil](/molmil-images/mine/4zyq) | |
2FFS
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![BU of 2ffs by Molmil](/molmil-images/mine/2ffs) | Structure of PR10-allergen-like protein PA1206 from Pseudomonas aeruginosa PAO1 | 分子名称: | hypothetical protein PA1206 | 著者 | Zimmerman, M.D, Chruszcz, M, Cymborowski, M.T, Wang, S, Kirillova, O, Skarina, T, Onopriyenko, O, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2005-12-20 | 公開日 | 2006-01-10 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of PR10-Allergen-Like Protein PA1206 From Pseudomonas aeruginosa PAO1 To be Published
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6AUM
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![BU of 6aum by Molmil](/molmil-images/mine/6aum) | Crystal structure of human soluble epoxide hydrolase complexed with trans-4-[4-(3-trifluoromethoxyphenyl-l-ureido)-cyclohexyloxy]-benzoic acid. | 分子名称: | 4-{[trans-4-({[4-(trifluoromethoxy)phenyl]carbamoyl}amino)cyclohexyl]oxy}benzoic acid, Bifunctional epoxide hydrolase 2, CHLORIDE ION, ... | 著者 | Kodani, S.D, Bahkta, S, Hwang, S.H, Pakhomova, S, Newcomer, M.E, Morisseau, C, Hammock, B. | 登録日 | 2017-09-01 | 公開日 | 2018-02-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. Bioorg. Med. Chem. Lett., 28, 2018
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6L81
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![BU of 6l81 by Molmil](/molmil-images/mine/6l81) | Crystal structure of Homo sapiens GCP5 N-terminus and Mozart1 | 分子名称: | Gamma-tubulin complex component 5, Mitotic-spindle organizing protein 1 | 著者 | Huang, T.L, Wang, H.J, Wang, S.W, Hsia, K.C. | 登録日 | 2019-11-04 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.19651 Å) | 主引用文献 | Promiscuous Binding of Microprotein Mozart1 to gamma-Tubulin Complex Mediates Specific Subcellular Targeting to Control Microtubule Array Formation. Cell Rep, 31, 2020
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6KYC
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![BU of 6kyc by Molmil](/molmil-images/mine/6kyc) | Structure of the S207A mutant of Clostridium difficile sortase B | 分子名称: | Putative peptidase C60B, sortase B | 著者 | Kang, C.Y, Huang, I.H, Wu, T.Y, Chang, J.C, Hsiao, Y.Y, Cheng, C.H, Tsai, W.J, Hsu, K.C, Wang, S.Y. | 登録日 | 2019-09-17 | 公開日 | 2020-02-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | 主引用文献 | Functional analysis ofClostridium difficilesortase B reveals key residues for catalytic activity and substrate specificity. J.Biol.Chem., 295, 2020
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6L80
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![BU of 6l80 by Molmil](/molmil-images/mine/6l80) | Crystal structure of pombe Mod21 N-terminus and Mozart1 | 分子名称: | Gamma-tubulin complex subunit mod21, Mitotic-spindle organizing protein 1 | 著者 | Huang, T.L, Wang, H.J, Wang, S.W, Hsia, K.C. | 登録日 | 2019-11-03 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.00049758 Å) | 主引用文献 | Promiscuous Binding of Microprotein Mozart1 to gamma-Tubulin Complex Mediates Specific Subcellular Targeting to Control Microtubule Array Formation. Cell Rep, 31, 2020
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3AKB
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![BU of 3akb by Molmil](/molmil-images/mine/3akb) | Structural basis for prokaryotic calcium-mediated regulation by a Streptomyces coelicolor calcium-binding protein | 分子名称: | CALCIUM ION, Putative calcium binding protein | 著者 | Zhao, X, Pang, H, Wang, S, Zhou, W, Yang, K, Bartlam, M. | 登録日 | 2010-07-09 | 公開日 | 2011-01-26 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural basis for prokaryotic calciummediated regulation by a Streptomyces coelicolor calcium binding protein Protein Cell, 1, 2010
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2IAI
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![BU of 2iai by Molmil](/molmil-images/mine/2iai) | Crystal structure of SCO3833, a member of the TetR transcriptional regulator family from Streptomyces coelicolor A3 | 分子名称: | Putative transcriptional regulator SCO3833 | 著者 | Zimmerman, M.D, Xu, X, Wang, S, Gu, J, Chruszcz, M, Cymborowski, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-09-08 | 公開日 | 2006-09-26 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of SCO3833, a member of the TetR transcriptional regulator family from Streptomyces coelicolor A3 To be Published
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