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PDB: 785 件

4EK7
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High speed X-ray analysis of plant enzymes at room temperature
分子名称: CHLORIDE ION, Raucaffricine-O-beta-D-glucosidase, beta-D-glucopyranose
著者Xia, L, Rajendran, C, Ruppert, M, Panjikar, S, Wang, M, Stoeckigt, J.
登録日2012-04-09
公開日2013-02-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献High speed X-ray analysis of plant enzymes at room temperature.
Phytochemistry, 2012
4FYP
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Crystal Structure of Plant Vegetative Storage Protein
分子名称: MAGNESIUM ION, Vegetative storage protein 1
著者Chen, Y, Wei, J, Wang, M, Gong, W, Zhang, M.
登録日2012-07-05
公開日2013-06-26
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of Arabidopsis VSP1 reveals the plant class C-like phosphatase structure of the DDDD superfamily of phosphohydrolases
Plos One, 7, 2012
4PW6
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structure of UHRF2-SRA in complex with a 5hmC-containing DNA, complex II
分子名称: 5hmC-containing DNA1, 5hmC-containing DNA2, E3 ubiquitin-protein ligase UHRF2
著者Zhou, T, Xiong, J, Wang, M, Yang, N, Wong, J, Zhu, B, Xu, R.M.
登録日2014-03-18
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.789 Å)
主引用文献Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Mol.Cell, 54, 2014
8IOW
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Cryo-EM structure of the sarilumab Fab/IL-6R complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Sarilumab Fab, Interleukin-6 receptor subunit alpha, ...
著者She, J, Chen, L, Wang, M.X.
登録日2023-03-13
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of the sarilumab Fab/IL-6R complex
To Be Published
8JIP
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Cryo-EM structure of the GLP-1R/GCGR dual agonist MEDI0382-bound human GLP-1R-Gs complex
分子名称: Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T.
登録日2023-05-27
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Structural analysis of the dual agonism at GLP-1R and GCGR.
Proc.Natl.Acad.Sci.USA, 120, 2023
3U57
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Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
分子名称: (2beta,7beta,16S,17R,19E,21beta)-21-(beta-D-glucopyranosyloxy)-2,7-dihydro-7,17-cyclosarpagan-17-yl acetate, CHLORIDE ION, Raucaffricine-O-beta-D-glucosidase
著者Xia, L, Ruppert, M, Wang, M, Panjikar, S, Lin, H, Rajendran, C, Barleben, L, Stoeckigt, J.
登録日2011-10-11
公開日2011-11-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structures of alkaloid biosynthetic glucosidases decode substrate specificity.
Acs Chem.Biol., 7, 2012
8JIR
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Cryo-EM structure of the GLP-1R/GCGR dual agonist SAR425899-bound human GLP-1R-Gs complex
分子名称: Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T.
登録日2023-05-27
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献Structural analysis of the dual agonism at GLP-1R and GCGR.
Proc.Natl.Acad.Sci.USA, 120, 2023
3U5Y
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Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
分子名称: CHLORIDE ION, Raucaffricine-O-beta-D-glucosidase, Secologanin
著者Xia, L, Ruppert, M, Wang, M, Panjikar, S, Lin, H, Rajendran, C, Barleben, L, Stoeckigt, J.
登録日2011-10-11
公開日2011-11-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of alkaloid biosynthetic glucosidases decode substrate specificity.
Acs Chem.Biol., 7, 2012
8JIT
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Cryo-EM structure of the GLP-1R/GCGR dual agonist MEDI0382-bound human GCGR-Gs complex
分子名称: Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T.
登録日2023-05-27
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Structural analysis of the dual agonism at GLP-1R and GCGR.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JIQ
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Cryo-EM structure of the GLP-1R/GCGR dual agonist Peptide 15-bound human GCGR-Gs complex
分子名称: Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T.
登録日2023-05-27
公開日2023-09-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural analysis of the dual agonism at GLP-1R and GCGR.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JIU
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Cryo-EM structure of the GLP-1R/GCGR dual agonist SAR425899-bound human GCGR-Gs complex
分子名称: Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T.
登録日2023-05-27
公開日2023-09-13
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Structural analysis of the dual agonism at GLP-1R and GCGR.
Proc.Natl.Acad.Sci.USA, 120, 2023
7C3M
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Structure of FERM protein
分子名称: Fermitin family homolog 3,Fermitin family homolog 3,Fermitin family homolog 3
著者Bu, W, Loh, Z.Y, Jin, S, Basu, S, Ero, R, Park, J.E, Yan, X, Wang, M, Sze, S.K, Tan, S.M, Gao, Y.G.
登録日2020-05-13
公開日2020-06-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural basis of human full-length kindlin-3 homotrimer in an auto-inhibited state.
Plos Biol., 18, 2020
8JIS
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Cryo-EM structure of the GLP-1R/GCGR dual agonist peptide15-bound human GLP-1R-Gs complex
分子名称: Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T.
登録日2023-05-27
公開日2023-11-08
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献Structural analysis of the dual agonism at GLP-1R and GCGR.
Proc.Natl.Acad.Sci.USA, 120, 2023
6LI6
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Crystal structure of MCR-1-S treated by Au(PEt3)Cl
分子名称: GOLD ION, Probable phosphatidylethanolamine transferase Mcr-1, TRIETHYLPHOSPHANE
著者Zhang, Q, Wang, M, Sun, H.
登録日2019-12-10
公開日2020-09-16
最終更新日2020-10-28
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin.
Nat Commun, 11, 2020
4EQ3
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Crystal Structure Analysis of Selenomethionine (Se-Met) Substituted Chicken Interferon Gamma Receptor Alpha Chain
分子名称: Interferon gamma receptor 1
著者Ping, Z, Qi, J, Lu, G, Shi, Y, Wang, X, Gao, G.F, Wang, M.
登録日2012-04-18
公開日2013-04-24
最終更新日2014-05-21
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Crystal structure of the interferon gamma receptor alpha chain from chicken reveals an undetected extra helix compared with the human counterparts.
J.Interferon Cytokine Res., 34, 2014
6LHE
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Crystal Structure of Gold-bound NDM-1
分子名称: GOLD ION, Metallo-beta-lactamase type 2, SULFATE ION
著者Wang, H, Sun, H, Wang, M.
登録日2019-12-07
公開日2020-09-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.206 Å)
主引用文献Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin.
Nat Commun, 11, 2020
3JUI
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Crystal Structure of the C-terminal Domain of Human Translation Initiation Factor eIF2B epsilon Subunit
分子名称: GLYCEROL, Translation initiation factor eIF-2B subunit epsilon
著者Wei, J, Xu, H, Zhang, C, Wang, M, Gao, F, Gong, W.
登録日2009-09-15
公開日2009-10-06
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the C-terminal Domain of Human Translation Initiation Factor eIF2B epsilon Subunit
To be published
3V0T
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Crystal Structure of Perakine Reductase, Founder Member of a Novel AKR Subfamily with Unique Conformational Changes during NADPH Binding
分子名称: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, Perakine Reductase
著者Sun, L, Chen, Y, Rajendran, C, Panjikar, S, Mueller, U, Wang, M, Rosenthal, C, Mindnich, R, Penning, T.M, Stoeckigt, J.
登録日2011-12-08
公開日2012-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.333 Å)
主引用文献Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
7DUR
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Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex
分子名称: CHOLESTEROL, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M.
登録日2021-01-11
公開日2021-08-11
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor.
Nat Commun, 12, 2021
6LI4
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Crystal structure of MCR-1-S
分子名称: Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION
著者Zhang, Q, Wang, M, Sun, H.
登録日2019-12-10
公開日2020-09-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin.
Nat Commun, 11, 2020
6LI5
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Crystal structure of apo-MCR-1-S
分子名称: Probable phosphatidylethanolamine transferase Mcr-1
著者Zhang, Q, Wang, M, Sun, H.
登録日2019-12-10
公開日2020-09-16
最終更新日2020-10-28
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin.
Nat Commun, 11, 2020
4GIQ
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Crystal Structure of mouse RANK bound to RANKL
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, SODIUM ION, ...
著者Nelson, C.A, Wang, M.W.-H, Fremont, D.H.
登録日2012-08-08
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor.
Structure, 20, 2012
3V0U
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Crystal Structure of Perakine Reductase, Founder Member of a Novel AKR Subfamily with Unique Conformational Changes during NADPH Binding
分子名称: Perakine reductase
著者Sun, L, Chen, Y, Rajendran, C, Panjikar, S, Mueller, U, Wang, M, Rosenthal, C, Mindnich, R, Penning, T.M, Stoeckigt, J.
登録日2011-12-08
公開日2012-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.203 Å)
主引用文献Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
6HY2
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Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase
分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, TRP-MET-LEU-ASP-PRO-ILE-ALA-GLY-LYS-TRP-SER-ARG
著者Williams, A.H, Dangkulwanich, M.
登録日2018-10-19
公開日2019-01-23
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase.
Sci Rep, 9, 2019
3QNN
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RB69 DNA Polymerase (Y567A) Ternary Complex with dGT Opposite 3tCo
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA Primer, ...
著者Xia, S, Wang, M, Wang, J, Konigsberg, W.H.
登録日2011-02-08
公開日2012-02-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Using a Fluorescent Cytosine Analogue tC(o) To Probe the Effect of the Y567 to Ala Substitution on the Preinsertion Steps of dNMP Incorporation by RB69 DNA Polymerase.
Biochemistry, 51, 2012

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