Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 946 件
7XYD
DownloadVisualize
BU of 7xyd by Molmil
Crystal structure of TMPRSS2 in complex with Nafamostat
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ...
著者Wang, H, Liu, X, Duan, Y, Liu, X, Sun, L, Yang, H.
登録日2022-06-01
公開日2023-12-06
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
7Y0F
DownloadVisualize
BU of 7y0f by Molmil
Crystal structure of TMPRSS2 in complex with UK-371804
分子名称: 2-[(1-carbamimidamido-4-chloranyl-isoquinolin-7-yl)sulfonylamino]-2-methyl-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H.
登録日2022-06-04
公開日2023-12-06
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
7Y0E
DownloadVisualize
BU of 7y0e by Molmil
Crystal structure of TMPRSS2 in complex with Camostat
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ...
著者Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H.
登録日2022-06-04
公開日2023-12-06
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
8EAV
DownloadVisualize
BU of 8eav by Molmil
YAR027W and YAR028W in complex with c subunits from yeast VO complex
分子名称: YAR027W or YAR028W, subunit from the c ring of yeast VO complex
著者Wang, H, Bueler, S.A, Rubinstein, J.L.
登録日2022-08-29
公開日2022-11-02
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EAT
DownloadVisualize
BU of 8eat by Molmil
Yeast VO missing subunits a, e, and f in complex with Vma12-22p
分子名称: V-type proton ATPase subunit F, V-type proton ATPase subunit c, V-type proton ATPase subunit c', ...
著者Wang, H, Bueler, S.A, Rubinstein, J.L.
登録日2022-08-29
公開日2022-11-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EAS
DownloadVisualize
BU of 8eas by Molmil
Yeast VO in complex with Vma12-22p
分子名称: V-type proton ATPase assembly factor Vma12p, V-type proton ATPase subunit F, V-type proton ATPase subunit a, ...
著者Wang, H, Bueler, S.A, Rubinstein, J.L.
登録日2022-08-29
公開日2022-11-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EAU
DownloadVisualize
BU of 8eau by Molmil
Yeast VO in complex with Vma21p
分子名称: V-type proton ATPase subunit a, vacuolar isoform, V-type proton ATPase subunit c, ...
著者Wang, H, Bueler, S.A, Rubinstein, J.L.
登録日2022-08-29
公開日2022-11-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p.
Proc.Natl.Acad.Sci.USA, 120, 2023
3X0T
DownloadVisualize
BU of 3x0t by Molmil
Crystal structure of PirA
分子名称: NITRATE ION, Uncharacterized protein
著者Wang, H.C, Ko, T.P, Wang, A.H.J, Lo, C.F.
登録日2014-10-22
公開日2015-08-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin.
Proc.Natl.Acad.Sci.USA, 112, 2015
6LHE
DownloadVisualize
BU of 6lhe by Molmil
Crystal Structure of Gold-bound NDM-1
分子名称: GOLD ION, Metallo-beta-lactamase type 2, SULFATE ION
著者Wang, H, Sun, H, Wang, M.
登録日2019-12-07
公開日2020-09-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.206 Å)
主引用文献Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin.
Nat Commun, 11, 2020
8CEO
DownloadVisualize
BU of 8ceo by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Wang, H, Cramer, P.
登録日2023-02-02
公開日2023-03-08
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
5AYR
DownloadVisualize
BU of 5ayr by Molmil
The crystal structure of SAUGI/human UDG complex
分子名称: MAGNESIUM ION, Uncharacterized protein, Uracil-DNA glycosylase
著者Wang, H.C, Ko, T.P, Huang, M.F, Wang, A.H.J.
登録日2015-09-02
公開日2016-06-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase.
Nucleic Acids Res., 44, 2016
5AYS
DownloadVisualize
BU of 5ays by Molmil
Crystal structure of SAUGI/HSV UDG complex
分子名称: Uncharacterized protein, Uracil-DNA glycosylase
著者Wang, H.C, Ko, T.P, Huang, M.F, Wang, A.H.J.
登録日2015-09-02
公開日2016-06-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase.
Nucleic Acids Res., 44, 2016
6O60
DownloadVisualize
BU of 6o60 by Molmil
Crystal structure of GGTase3-FBXL2-SKP1 complex
分子名称: F-box/LRR-repeat protein 2, Geranylgeranyl transferase type-2 subunit beta, Protein prenyltransferase alpha subunit repeat-containing protein 1, ...
著者Wang, H, Zheng, N.
登録日2019-03-04
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase.
Nat.Struct.Mol.Biol., 26, 2019
3K3H
DownloadVisualize
BU of 3k3h by Molmil
Crystal structure of the PDE9A catalytic domain in complex with (S)-BAY73-6691
分子名称: 1-(2-chlorophenyl)-6-[(2S)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ...
著者Wang, H, Luo, X, Ye, M, Hou, J, Robinson, H, Ke, H.
登録日2009-10-02
公開日2010-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insight into Binding of Phosphodiesterase-9A Selective Inhibitors by Crystal Structures and Mutagenesis
J.Med.Chem., 53, 2010
3K3E
DownloadVisualize
BU of 3k3e by Molmil
Crystal structure of the PDE9A catalytic domain in complex with (R)-BAY73-6691
分子名称: 1-(2-chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ...
著者Wang, H, Luo, X, Ye, M, Hou, J, Robinson, H, Ke, H.
登録日2009-10-02
公開日2010-02-16
最終更新日2013-11-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Insight into Binding of Phosphodiesterase-9A Selective Inhibitors by Crystal Structures and Mutagenesis
J.Med.Chem., 53, 2010
7MOM
DownloadVisualize
BU of 7mom by Molmil
Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) in complex with a metaphosphate intermediate
分子名称: BETA-MERCAPTOETHANOL, PHOSPHITE ION, Tyrosine-protein phosphatase DSP1
著者Wang, H, Shears, S.B.
登録日2021-05-01
公開日2022-03-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Nat Commun, 13, 2022
7MOL
DownloadVisualize
BU of 7mol by Molmil
Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) in complex with phosphate in conformation B (Pi(B))
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PHOSPHATE ION, Tyrosine-protein phosphatase DSP1
著者Wang, H, Shears, S.B.
登録日2021-05-01
公開日2022-03-02
最終更新日2022-05-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Nat Commun, 13, 2022
7MOK
DownloadVisualize
BU of 7mok by Molmil
Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) in Complex with Phosphate in Conformation A (Pi(A))
分子名称: BETA-MERCAPTOETHANOL, PHOSPHATE ION, Tyrosine-protein phosphatase DSP1
著者Wang, H, Shears, S.B.
登録日2021-05-01
公開日2022-03-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Nat Commun, 13, 2022
8CEN
DownloadVisualize
BU of 8cen by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Wang, H, Schilbach, S, Cramer, P.
登録日2023-02-02
公開日2023-03-22
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
6S01
DownloadVisualize
BU of 6s01 by Molmil
Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome
分子名称: Histone H2A, Histone H2B 1.1, Histone H3, ...
著者Wang, H, Farnung, L, Dienemann, C, Cramer, P.
登録日2019-06-13
公開日2019-12-18
最終更新日2020-01-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding.
Nat.Struct.Mol.Biol., 27, 2020
6T9J
DownloadVisualize
BU of 6t9j by Molmil
SAGA Tra1 module
分子名称: Transcription factor SPT20, Transcription initiation factor TFIID subunit 12, Transcription-associated protein 1
著者Wang, H, Cheung, A, Cramer, P.
登録日2019-10-28
公開日2020-01-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of the transcription coactivator SAGA.
Nature, 577, 2020
3X0U
DownloadVisualize
BU of 3x0u by Molmil
Crystal structure of PirB
分子名称: Uncharacterized protein
著者Wang, H.C, Ko, T.P, Wang, A.H.J, Lo, C.F.
登録日2014-10-22
公開日2015-08-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin.
Proc.Natl.Acad.Sci.USA, 112, 2015
3KUZ
DownloadVisualize
BU of 3kuz by Molmil
Crystal structure of the ubiquitin like domain of PLXNC1
分子名称: Plexin-C1, UNKNOWN ATOM OR ION
著者Wang, H, Li, B, Tempel, W, Tong, Y, Guan, X, Zhong, N, Crombet, L, MacKenzie, F, Buck, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2009-11-28
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the ubiquitin like domain of PLXNC1
to be published
3VK0
DownloadVisualize
BU of 3vk0 by Molmil
Crystal Structure of hypothetical transcription factor NHTF from Neisseria
分子名称: Transcriptional regulator
著者Wang, H.-C, Ko, T.-P, Wu, M.-L, Wu, H.-J, Ku, S.-C, Wang, A.H.-J.
登録日2011-11-01
公開日2012-03-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Neisseria conserved protein DMP19 is a DNA mimic protein that prevents DNA binding to a hypothetical nitrogen-response transcription factor
Nucleic Acids Res., 2012
6IO4
DownloadVisualize
BU of 6io4 by Molmil
Silver-bound Glyceraldehyde-3-phosphate dehydrogenase A
分子名称: Glyceraldehyde-3-phosphate dehydrogenase A, SILVER ION
著者Wang, H, Sun, H, Wang, M.
登録日2018-10-29
公開日2019-07-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis ofE. coli.
Chem Sci, 10, 2019

222415

件を2024-07-10に公開中

PDB statisticsPDBj update infoContact PDBjnumon