5JDT
| Structure of Spin-labelled T4 lysozyme mutant L118C-R1 at 100K | 分子名称: | AZIDE ION, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | 著者 | Loll, B, Consentius, P, Gohlke, U, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T. | 登録日 | 2016-04-17 | 公開日 | 2016-09-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Tracking Transient Conformational States of T4 Lysozyme at Room Temperature Combining X-ray Crystallography and Site-Directed Spin Labeling. J.Am.Chem.Soc., 138, 2016
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7PX3
| Structure of U5 snRNP assembly and recycling factor TSSC4 in complex with BRR2 and Jab1 domain of PRPF8 | 分子名称: | Pre-mRNA-processing-splicing factor 8, Protein TSSC4, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Bergfort, A, Kuropka, B, Ilik, I.A, Freund, C, Aktas, T, Hilal, T, Weber, G, Wahl, M.C. | 登録日 | 2021-10-07 | 公開日 | 2022-01-26 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling. Nucleic Acids Res., 50, 2022
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4XHV
| Crystal structure of Drosophila Spinophilin-PDZ and a C-terminal peptide of Neurexin | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, LP20995p, ... | 著者 | Driller, J.H, Muhammad, K.G.H, Reddy, S, Rey, U, Boehme, M.A, Hollmann, C, Ramesh, N, Depner, H, Luetzkendorf, J, Matkovic, T, Bergeron, D, Quentin, C, Schmoranzer, J, Goettfert, F, Holt, M, Wahl, M.C, Hell, S.W, Walter, A, Sigrist, S.J, Loll, B. | 登録日 | 2015-01-06 | 公開日 | 2015-07-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function. Nat Commun, 6, 2015
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4Y0Y
| Trypsin in complex with with BPTI | 分子名称: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | 著者 | Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. | 登録日 | 2015-02-06 | 公開日 | 2015-06-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Fluorine teams up with water to restore inhibitor activity to mutant BPTI. Chem Sci, 6, 2015
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4Y0Z
| Trypsin in complex with with BPTI mutant AMINOBUTYRIC ACID | 分子名称: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | 著者 | Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. | 登録日 | 2015-02-06 | 公開日 | 2015-06-24 | 最終更新日 | 2018-04-18 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Fluorine teams up with water to restore inhibitor activity to mutant BPTI. Chem Sci, 6, 2015
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6IB8
| Structure of a complex of SuhB and NusA AR2 domain | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, Inositol-1-monophosphatase, ... | 著者 | Huang, Y.H, Loll, B, Wahl, M.C. | 登録日 | 2018-11-29 | 公開日 | 2019-04-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.646 Å) | 主引用文献 | Structural basis for the function of SuhB as a transcription factor in ribosomal RNA synthesis. Nucleic Acids Res., 47, 2019
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6IB7
| Structure of wild type SuhB | 分子名称: | GLYCEROL, Inositol-1-monophosphatase, MAGNESIUM ION | 著者 | Huang, Y.H, Loll, B, Wahl, M.C. | 登録日 | 2018-11-29 | 公開日 | 2019-04-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | 主引用文献 | Structural basis for the function of SuhB as a transcription factor in ribosomal RNA synthesis. Nucleic Acids Res., 47, 2019
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7OS1
| Cryo-EM structure of Brr2 in complex with Fbp21 | 分子名称: | U5 small nuclear ribonucleoprotein 200 kDa helicase, WW domain-binding protein 4 | 著者 | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | 登録日 | 2021-06-07 | 公開日 | 2022-02-23 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling. Nucleic Acids Res., 50, 2022
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7OS2
| Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78 | 分子名称: | Pre-mRNA-processing-splicing factor 8, Telomere length and silencing protein 1 homolog, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | 登録日 | 2021-06-07 | 公開日 | 2022-02-23 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling. Nucleic Acids Res., 50, 2022
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5T73
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4F92
| Brr2 Helicase Region S1087L | 分子名称: | SULFANILAMIDE, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C. | 登録日 | 2012-05-18 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.662 Å) | 主引用文献 | Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome. Proc.Natl.Acad.Sci.USA, 109, 2012
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4F91
| Brr2 Helicase Region | 分子名称: | U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C. | 登録日 | 2012-05-18 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.697 Å) | 主引用文献 | Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome. Proc.Natl.Acad.Sci.USA, 109, 2012
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4F93
| Brr2 Helicase Region S1087L, Mg-ATP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C. | 登録日 | 2012-05-18 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome. Proc.Natl.Acad.Sci.USA, 109, 2012
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1HH2
| Crystal structure of NusA from Thermotoga maritima | 分子名称: | N UTILIZATION SUBSTANCE PROTEIN A | 著者 | Worbs, M, Bourenkov, G.P, Bartunik, H.D, Huber, R, Wahl, M.C. | 登録日 | 2000-12-18 | 公開日 | 2001-10-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | An Extended RNA Binding Surface Through Arrayed S1 and Kh Domains in Transcription Factor Nusa Mol.Cell, 7, 2001
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8Q3Q
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8Q3O
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8Q3N
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8Q3P
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8PDY
| E. coli RNA polymerase paused at ops site | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | 登録日 | 2023-06-13 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8PEN
| fully recruited RfaH bound to E. coli transcription complex paused at ops site (alternative state of RfaH) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | 登録日 | 2023-06-14 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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2V9V
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2WFI
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2X7K
| The crystal structure of PPIL1 in complex with cyclosporine A suggests a binding mode for SKIP | 分子名称: | CADMIUM ION, CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 1, ... | 著者 | Stegmann, C.M, Luehrmann, R, Wahl, M.C. | 登録日 | 2010-03-01 | 公開日 | 2010-03-23 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | The Crystal Structure of Ppil1 Bound to Cyclosporine a Suggests a Binding Mode for a Linear Epitope of the Skip Protein. Plos One, 5, 2010
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2WFJ
| Atomic resolution crystal structure of the PPIase domain of human cyclophilin G in complex with cyclosporin A. | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, CYCLOSPORIN A, ... | 著者 | Stegmann, C.M, Sheldrick, G.M, Wahl, M.C. | 登録日 | 2009-04-06 | 公開日 | 2009-06-16 | 最終更新日 | 2019-05-22 | 実験手法 | X-RAY DIFFRACTION (0.75 Å) | 主引用文献 | The Thermodynamic Influence of Trapped Water Molecules on a Protein-Ligand Interaction. Angew.Chem.Int.Ed.Engl., 48, 2009
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438D
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