6XC2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xc2 by Molmil](/molmil-images/mine/6xc2) | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC12.1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 heavy chain, CC12.1 light chain, ... | Authors: | Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. | Deposit date: | 2020-06-08 | Release date: | 2020-07-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.112 Å) | Cite: | Structural basis of a shared antibody response to SARS-CoV-2. Science, 369, 2020
|
|
6WG0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wg0 by Molmil](/molmil-images/mine/6wg0) | |
6XC4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xc4 by Molmil](/molmil-images/mine/6xc4) | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC12.3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 heavy chain, CC12.3 light chain, ... | Authors: | Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. | Deposit date: | 2020-06-08 | Release date: | 2020-07-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.341 Å) | Cite: | Structural basis of a shared antibody response to SARS-CoV-2. Science, 369, 2020
|
|
6WFW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wfw by Molmil](/molmil-images/mine/6wfw) | Crystal structure of Fab364 in complex with NPNA2 peptide from circumsporozoite protein | Descriptor: | Fab364 heavy chain, Fab364 light chain, Immunoglobulin G-binding protein G, ... | Authors: | Pholcharee, T, Oyen, D, Wilson, I.A. | Deposit date: | 2020-04-04 | Release date: | 2020-07-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.093 Å) | Cite: | Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum. Nat Commun, 12, 2021
|
|
6WG2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wg2 by Molmil](/molmil-images/mine/6wg2) | |
1Z5L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z5l by Molmil](/molmil-images/mine/1z5l) | Structure of a highly potent short-chain galactosyl ceramide agonist bound to CD1D | Descriptor: | (2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zajonc, D.M, Cantu, C, Mattner, J, Zhou, D, Savage, P.B, Bendelac, A, Wilson, I.A, Teyton, L. | Deposit date: | 2005-03-18 | Release date: | 2005-07-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor. Nat.Immunol., 6, 2005
|
|
1Y18
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y18 by Molmil](/molmil-images/mine/1y18) | Fab fragment of catalytic elimination antibody 34E4 E(H50)D mutant in complex with hapten | Descriptor: | 2-AMINO-5,6-DIMETHYL-BENZIMIDAZOLE-1-PENTANOIC ACID, CHLORIDE ION, Catalytic antibody 34E4 heavy chain, ... | Authors: | Debler, E.W, Ito, S, Heine, A, Wilson, I.A. | Deposit date: | 2004-11-17 | Release date: | 2005-04-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural origins of efficient proton abstraction from carbon by a catalytic antibody Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
1XZ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xz0 by Molmil](/molmil-images/mine/1xz0) | Crystal structure of CD1a in complex with a synthetic mycobactin lipopeptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(HYDROXY-HEXADECANOYL-AMINO)-2-{[(4S)-2-(2-HYDROXY-PHENYL)-4,5-DIHYDRO-OXAZOLE-4-CARBONYL]-AMINO}-HEXANOIC ACID 2-[(3S)-1-(TERT-BUTYL-DIPHENYL-SILANYLOXY)-2-OXO-AZEPAN-3-YLCARBAMOYL]-(1S)-1-METHYL-ETHYL ESTER, Beta-2-microglobulin, ... | Authors: | Zajonc, D.M, Crispin, M.D, Bowden, T.A, Young, D.C, Cheng, T.Y, Hu, J, Costello, C.E, Miller, M.J, Moody, D.B, Wilson, I.A. | Deposit date: | 2004-11-11 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular Mechanism of Lipopeptide Presentation by CD1a. Immunity, 22, 2005
|
|
2AFE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2afe by Molmil](/molmil-images/mine/2afe) | Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence | Descriptor: | protein Asl1650 | Authors: | Johnson, M.A, Peti, W, Herrmann, T, Wilson, I.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG) | Deposit date: | 2005-07-25 | Release date: | 2005-08-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence Protein Sci., 15, 2006
|
|
1Y0L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y0l by Molmil](/molmil-images/mine/1y0l) | Catalytic elimination antibody 34E4 in complex with hapten | Descriptor: | 2-AMINO-5,6-DIMETHYL-BENZIMIDAZOLE-1-PENTANOIC ACID, CHLORIDE ION, Catalytic Antibody Fab 34E4 Heavy chain, ... | Authors: | Debler, E.W, Ito, S, Heine, A, Wilson, I.A. | Deposit date: | 2004-11-15 | Release date: | 2005-04-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural origins of efficient proton abstraction from carbon by a catalytic antibody Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
1ZXT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zxt by Molmil](/molmil-images/mine/1zxt) | Crystal Structure of A Viral Chemokine | Descriptor: | functional macrophage inflammatory protein 1-alpha homolog | Authors: | Luz, J.G, Yu, M, Su, Y, Wu, Z, Zhou, Z, Sun, R, Wilson, I.A. | Deposit date: | 2005-06-08 | Release date: | 2005-08-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A. J.Mol.Biol., 352, 2005
|
|
2AFD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2afd by Molmil](/molmil-images/mine/2afd) | Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence | Descriptor: | protein Asl1650 | Authors: | Johnson, M.A, Peti, W, Herrmann, T, Wilson, I.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG) | Deposit date: | 2005-07-25 | Release date: | 2005-08-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence Protein Sci., 15, 2006
|
|
2AJV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ajv by Molmil](/molmil-images/mine/2ajv) | |
2AJS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ajs by Molmil](/molmil-images/mine/2ajs) | Crystal structure of cocaine catalytic antibody 7A1 Fab' in complex with heptaethylene glycol | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Antibody 7A1 FAB', GLYCEROL, ... | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2005-08-02 | Release date: | 2006-02-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Complete reaction cycle of a cocaine catalytic antibody at atomic resolution. Structure, 14, 2006
|
|
2AJZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ajz by Molmil](/molmil-images/mine/2ajz) | |
4DGV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4dgv by Molmil](/molmil-images/mine/4dgv) | Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody HCV1, P2(1) form | Descriptor: | E2 peptide, HCV1 Heavy Chain, HCV1 Light Chain, ... | Authors: | Kong, L, Wilson, I.A, Law, M. | Deposit date: | 2012-01-26 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.805 Å) | Cite: | Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4DGY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4dgy by Molmil](/molmil-images/mine/4dgy) | Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody HCV1, C2 form | Descriptor: | CHLORIDE ION, E2 peptide, GLYCEROL, ... | Authors: | Kong, L, Wilson, I.A, Law, M. | Deposit date: | 2012-01-27 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4EW1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ew1 by Molmil](/molmil-images/mine/4ew1) | High resolution structure of human glycinamide ribonucleotide transformylase in apo form. | Descriptor: | PHOSPHATE ION, SULFATE ION, Trifunctional purine biosynthetic protein adenosine-3 | Authors: | Connelly, S, DeMartino, K, Boger, D.L, Wilson, I.A. | Deposit date: | 2012-04-26 | Release date: | 2013-07-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.522 Å) | Cite: | Biological and Structural Evaluation of 10R- and 10S-Methylthio-DDACTHF Reveals a New Role for Sulfur in Inhibition of Glycinamide Ribonucleotide Transformylase. Biochemistry, 52, 2013
|
|
4EW3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ew3 by Molmil](/molmil-images/mine/4ew3) | The structure of human glycinamide ribonucleotide transformylase in complex with 10R-methylthio-DDATHF. | Descriptor: | N-({4-[(1R)-4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-(methylsulfanyl)butyl]phenyl}carbonyl)-L-glutamic acid, PHOSPHATE ION, SULFATE ION, ... | Authors: | Connelly, S, DeMartino, K, Boger, D.L, Wilson, I.A. | Deposit date: | 2012-04-26 | Release date: | 2013-07-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.702 Å) | Cite: | Biological and Structural Evaluation of 10R- and 10S-Methylthio-DDACTHF Reveals a New Role for Sulfur in Inhibition of Glycinamide Ribonucleotide Transformylase. Biochemistry, 52, 2013
|
|
2B1I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b1i by Molmil](/molmil-images/mine/2b1i) | crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase | Descriptor: | Bifunctional purine biosynthesis protein PURH, POTASSIUM ION, [3,4-DIHYDROXY-5R-(2,2,4-TRIOXO-1,2R,3S,4R-TETRAHYDRO-2L6-IMIDAZO[4,5-C][1,2,6]THIADIAZIN-7-YL)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN PHOSPHATE | Authors: | Xu, L, Chong, Y, Hwang, I, D'Onofrio, A, Amore, K, Beardsley, G.P, Li, C, Olson, A.J, Boger, D.L, Wilson, I.A. | Deposit date: | 2005-09-15 | Release date: | 2006-11-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase. J.Biol.Chem., 282, 2007
|
|
2B1G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b1g by Molmil](/molmil-images/mine/2b1g) | Crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase | Descriptor: | 7-(3,4-DIHYDROXY-5R-HYDROXYMETHYLTETRAHYDROFURAN-2-YL)-2,2-DIOXO-1,2R,3R,7-TETRAHYDRO-2L6-IMIDAZO[4,5-C][1,2,6]THIADIAZIN-4S-ONE, Bifunctional purine biosynthesis protein PURH, PHOSPHATE ION, ... | Authors: | Xu, L, Chong, Y, Hwang, I, D'Onofrio, A, Amore, K, Beardsley, G.P, Li, C, Olson, A.J, Boger, D.L, Wilson, I.A. | Deposit date: | 2005-09-15 | Release date: | 2006-11-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase. J.Biol.Chem., 282, 2007
|
|
4EW2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ew2 by Molmil](/molmil-images/mine/4ew2) | The structure of human glycinamide ribonucleotide transformylase in complex with 10S-methylthio-DDATHF. | Descriptor: | N-({4-[(1S)-4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-(methylsulfanyl)butyl]phenyl}carbonyl)-L-glutamic acid, PHOSPHATE ION, SULFATE ION, ... | Authors: | Connelly, S, DeMartino, K, Boger, D.L, Wilson, I.A. | Deposit date: | 2012-04-26 | Release date: | 2013-07-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.602 Å) | Cite: | Biological and Structural Evaluation of 10R- and 10S-Methylthio-DDACTHF Reveals a New Role for Sulfur in Inhibition of Glycinamide Ribonucleotide Transformylase. Biochemistry, 52, 2013
|
|
4EEF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4eef by Molmil](/molmil-images/mine/4eef) | |
4F3Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4f3z by Molmil](/molmil-images/mine/4f3z) | Crystal structure of a swine H1N2 influenza virus hemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Xu, R, Wilson, I.A. | Deposit date: | 2012-05-09 | Release date: | 2012-07-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Functional Balance of the Hemagglutinin and Neuraminidase Activities Accompanies the Emergence of the 2009 H1N1 Influenza Pandemic. J.Virol., 86, 2012
|
|
4F6N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4f6n by Molmil](/molmil-images/mine/4f6n) | Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA | Descriptor: | DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM)P*GP*GP*TP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'), GLYCEROL, ... | Authors: | Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E. | Deposit date: | 2012-05-15 | Release date: | 2012-09-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|