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PDB: 882 件
2O5Z
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Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab 5-beta-androstane-3,17-dione complex
分子名称: 5-BETA-ANDROSTANE-3,17-DIONE, SULFATE ION, chimeric antibody Fab 1E9-DB3
著者Verdino, P, Wilson, I.A.
登録日2006-12-06
公開日2007-12-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3IMU
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Transthyretin in complex with (E)-4-(3-aminostyryl)-2,6-dibromoaniline
分子名称: 4-[(E)-2-(3-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
2OJZ
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Anti-DNA antibody ED10
分子名称: Fab ED10 heavy chain, Fab ED10 light chain
著者Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
登録日2007-01-15
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
2O5X
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Crystal structure of 1E9 LeuH47Trp/ArgH100Trp, an engineered Diels-Alderase Fab with nM steroid-binding affinity
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, chimeric antibody Fab 1E9-DB3
著者Verdino, P, Wilson, I.A.
登録日2006-12-06
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3J5M
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Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs
分子名称: BG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 heavy chain, ...
著者Lyumkis, D, Julien, J.-P, Wilson, I.A, Ward, A.B.
登録日2013-10-26
公開日2013-11-13
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
2OK0
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Fab ED10-DNA complex
分子名称: 5'-D(*TP*C)-3', Fab ED10 heavy chain, Fab ED10 light chain
著者Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
登録日2007-01-15
公開日2007-06-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
2OP4
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Crystal Structure of Quorum-Quenching Antibody 1G9
分子名称: 1,2-ETHANEDIOL, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, Murine Antibody Fab RS2-1G9 Lambda Light Chain
著者Kirchdoerfer, R.N, Debler, E.W, Wilson, I.A.
登録日2007-01-26
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
2OQJ
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Crystal structure analysis of Fab 2G12 in complex with peptide 2G12.1
分子名称: Fab 2G12 heavy chain, Fab 2G12 light chain, peptide 2G12.1 (ACPPSHVLDMRSGTCLAAEGK)
著者Calarese, D.A, Stanfield, R.L, Menendez, A, Scott, J.K, Wilson, I.A.
登録日2007-01-31
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120.
Faseb J., 22, 2008
2NTF
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Crystal Structure of a Quorum-Quenching Antibody in Complex with an N-Acyl-L-Homoserine Lactone Analog
分子名称: 3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, Murine Antibody Fab RS2-1G9 Lambda Light Chain
著者Debler, E.W, Wilson, I.A.
登録日2006-11-07
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
3GMN
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Structure of mouse CD1d in complex with C10Ph
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
著者Schiefner, A, Wilson, I.A.
登録日2009-03-14
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
3GML
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Structure of mouse CD1d in complex with C6Ph
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
著者Schiefner, A, Wilson, I.A.
登録日2009-03-14
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
1Y18
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Fab fragment of catalytic elimination antibody 34E4 E(H50)D mutant in complex with hapten
分子名称: 2-AMINO-5,6-DIMETHYL-BENZIMIDAZOLE-1-PENTANOIC ACID, CHLORIDE ION, Catalytic antibody 34E4 heavy chain, ...
著者Debler, E.W, Ito, S, Heine, A, Wilson, I.A.
登録日2004-11-17
公開日2005-04-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural origins of efficient proton abstraction from carbon by a catalytic antibody
Proc.Natl.Acad.Sci.USA, 102, 2005
3IMV
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BU of 3imv by Molmil
Transthyretin in complex with (E)-4-(4-aminostyryl)-2,6-dibromoaniline
分子名称: 4-[(E)-2-(4-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
2AFE
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Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence
分子名称: protein Asl1650
著者Johnson, M.A, Peti, W, Herrmann, T, Wilson, I.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
登録日2005-07-25
公開日2005-08-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence
Protein Sci., 15, 2006
1ZXT
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Crystal Structure of A Viral Chemokine
分子名称: functional macrophage inflammatory protein 1-alpha homolog
著者Luz, J.G, Yu, M, Su, Y, Wu, Z, Zhou, Z, Sun, R, Wilson, I.A.
登録日2005-06-08
公開日2005-08-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A.
J.Mol.Biol., 352, 2005
2PRT
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BU of 2prt by Molmil
Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
分子名称: DNA (5'-D(*CP*AP*GP*AP*CP*GP*CP*CP*CP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*GP*GP*GP*CP*GP*TP*CP*TP*G)-3'), Wilms tumor 1, ...
著者Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
登録日2007-05-04
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
2O5Y
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Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab progesterone complex
分子名称: PROGESTERONE, SULFATE ION, chimeric antibody Fab 1E9-DB3
著者Verdino, P, Wilson, I.A.
登録日2006-12-06
公開日2007-12-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1Y0L
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Catalytic elimination antibody 34E4 in complex with hapten
分子名称: 2-AMINO-5,6-DIMETHYL-BENZIMIDAZOLE-1-PENTANOIC ACID, CHLORIDE ION, Catalytic Antibody Fab 34E4 Heavy chain, ...
著者Debler, E.W, Ito, S, Heine, A, Wilson, I.A.
登録日2004-11-15
公開日2005-04-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural origins of efficient proton abstraction from carbon by a catalytic antibody
Proc.Natl.Acad.Sci.USA, 102, 2005
2AFD
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BU of 2afd by Molmil
Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence
分子名称: protein Asl1650
著者Johnson, M.A, Peti, W, Herrmann, T, Wilson, I.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
登録日2005-07-25
公開日2005-08-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence
Protein Sci., 15, 2006
2AJV
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Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with Cocaine
分子名称: Antibody 7A1 Fab', COCAINE
著者Zhu, X, Wilson, I.A.
登録日2005-08-02
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2Q7Y
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Structure of the endogenous iNKT cell ligand iGb3 bound to mCD1d
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Zajonc, D.M, Wilson, I.A, Teyton, L.
登録日2007-06-07
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Valpha14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids.
J.Mol.Biol., 377, 2008
2QGE
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Human transthyretin (TTR) complexed with 2-(3,5-Dimethylphenyl)benzoxazole
分子名称: 2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2007-06-28
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
2QGB
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Human transthyretin (TTR) in Apo-form
分子名称: Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2007-06-28
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
2QGD
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Human transthyretin (TTR) complexed with 2-(3,5-Dibromo-4-hydroxyphenyl)benzoxazole
分子名称: 4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2007-06-28
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
3L4B
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Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritima
分子名称: ADENOSINE MONOPHOSPHATE, TrkA K+ Channel protein TM1088A, TrkA K+ Channel protein TM1088B, ...
著者Deller, M.C, Johnson, H.A, Miller, M, Spraggon, G, Wilson, I.A, Lesley, S.A, Joint Center for Structural Genomics (JCSG)
登録日2009-12-18
公開日2010-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritima
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