7E4R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e4r by Molmil](/molmil-images/mine/7e4r) | Crystal structure of tubulin in complex with D-DM1-SMe | Descriptor: | (10E,12E)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-methyl-N-(3-(methylsulfinothioyl)propanoyl)-D-alaninate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Wang, Y, Li, W. | Deposit date: | 2021-02-15 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | C3 ester side chain plays a pivotal role in the antitumor activity of Maytansinoids. Biochem.Biophys.Res.Commun., 566, 2021
|
|
2JOW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jow by Molmil](/molmil-images/mine/2jow) | Differences in the electrostatic surfaces of the type III secretion needle proteins | Descriptor: | Protein prgI | Authors: | Wang, Y, Ouellette, A.N, Egan, C.W, De Guzman, R.N. | Deposit date: | 2007-04-06 | Release date: | 2007-07-24 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Differences in the Electrostatic Surfaces of the Type III Secretion Needle Proteins PrgI, BsaL, and MxiH J.Mol.Biol., 371, 2007
|
|
7EN3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7en3 by Molmil](/molmil-images/mine/7en3) | Crystal structure of tubulin in complex with Tubulysin analogue TGL | Descriptor: | (2S,4R)-5-(4-fluorophenyl)-2-methyl-4-[[2-[(1R,3R)-4-methyl-3-[5-methylhexyl-[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidin-2-yl]carbonylamino]pentanoyl]amino]-1-oxidanyl-pentyl]-1,3-thiazol-4-yl]carbonylamino]pentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Wang, Y, Li, W. | Deposit date: | 2021-04-15 | Release date: | 2022-04-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.643 Å) | Cite: | The X-ray structure of tubulysin analogue TGL in complex with tubulin and three possible routes for the development of next-generation tubulysin analogues. Biochem.Biophys.Res.Commun., 565, 2021
|
|
7E4P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e4p by Molmil](/molmil-images/mine/7e4p) | Crystal structure of tubulin in complex with Ansamitocin P3 | Descriptor: | (1S,2S,3S,5S,6S,16Z,18Z,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl 2-methylpropanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Wang, Y, Li, W. | Deposit date: | 2021-02-14 | Release date: | 2022-02-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | C3 Ester Side Chain Plays a Pivotal Role in the Antitumor Activity of Maytansinoids To Be Published
|
|
7E4Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e4y by Molmil](/molmil-images/mine/7e4y) | Crystal structure of tubulin in complex with L-DM4-SMe | Descriptor: | (1S,2S,3S,5R,6S,16E,18E,20S,21R)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl (2S)-2-{methyl[3-methyl-3-(methyldisulfanyl)butanoyl]amino}propanoate (non-preferred name), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Wang, Y, Li, W. | Deposit date: | 2021-02-16 | Release date: | 2022-02-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.708 Å) | Cite: | C3 Ester Side Chain Plays a Pivotal Role in the Antitumor Activity of Maytansinoids To Be Published
|
|
2IVH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ivh by Molmil](/molmil-images/mine/2ivh) | Crystal structure of the nuclease domain of ColE7 (H545Q mutant) in complex with an 18-bp duplex DNA | Descriptor: | 5'-D(*GP*GP*AP*AP*TP*TP*CP*GP*AP*TP *CP*GP*AP*AP*TP*TP*CP*C)-3', COLCIN-E7, ZINC ION | Authors: | Wang, Y.T, Yang, W.J, Li, C.L, Doudeva, L.G, Yuan, H.S. | Deposit date: | 2006-06-13 | Release date: | 2007-01-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases. Nucleic Acids Res., 35, 2007
|
|
2IVK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ivk by Molmil](/molmil-images/mine/2ivk) | Crystal structure of the periplasmic endonuclease Vvn complexed with a 16-bp DNA | Descriptor: | 5'-D(*AP*AP*TP*TP*CP*GP*AP*TP*CP*GP *AP*AP*TP*TP*C)-3', 5'-D(*GP*AP*AP*TP*TP*CP*GP*AP*TP*CP *GP*AP*AP*TP*T)-3', 5'-D(*GP*AP*AP*TP*TP*CP*GP*AP*TP*CP *GP*AP*AP*TP*TP*C)-3', ... | Authors: | Wang, Y.T, Yang, W.J, Li, C.L, Doudeva, L.G, Yuan, H.S. | Deposit date: | 2006-06-14 | Release date: | 2007-01-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases. Nucleic Acids Res., 35, 2007
|
|
2IL3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2il3 by Molmil](/molmil-images/mine/2il3) | Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity | Descriptor: | Epsilon-class Glutathione S-transferase | Authors: | Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L. | Deposit date: | 2006-10-02 | Release date: | 2007-10-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity J.Struct.Biol., 164, 2008
|
|
2IMK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2imk by Molmil](/molmil-images/mine/2imk) | Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity | Descriptor: | Epsilon-class Glutathione S-transferase, S-HEXYLGLUTATHIONE | Authors: | Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L. | Deposit date: | 2006-10-02 | Release date: | 2007-10-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity J.Struct.Biol., 164, 2008
|
|
2K48
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2k48 by Molmil](/molmil-images/mine/2k48) | NMR Structure of the N-terminal Coiled Coil Domain of the Andes Hantavirus Nucleocapsid Protein | Descriptor: | Nucleoprotein | Authors: | Wang, Y, Boudreaux, D.M, Estrada, D.F, Egan, C.W, St Jeor, S.C, De Guzman, R.N. | Deposit date: | 2008-05-30 | Release date: | 2008-08-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR Structure of the N-terminal Coiled Coil Domain of the Andes Hantavirus Nucleocapsid Protein. J.Biol.Chem., 283, 2008
|
|
2M5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m5i by Molmil](/molmil-images/mine/2m5i) | |
2KKT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kkt by Molmil](/molmil-images/mine/2kkt) | Solution structure of the SCA7 domain of human Ataxin-7-L3 protein | Descriptor: | Ataxin-7-like protein 3, ZINC ION | Authors: | Wang, Y, Atkinson, A.R, Bonnet, J, Romier, C, Kieffer, B. | Deposit date: | 2009-06-29 | Release date: | 2010-06-16 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Histone deubiquitination by SAGA is modulated by an atypical zinc finger domain of Ataxin-7 To be Published
|
|
7EF1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ef1 by Molmil](/molmil-images/mine/7ef1) | |
7EEZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7eez by Molmil](/molmil-images/mine/7eez) | crystal structure of maize SHH2 SAWADEE domain | Descriptor: | HB transcription factor, ZINC ION | Authors: | Wang, Y, Du, J. | Deposit date: | 2021-03-20 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Recognition of H3K9me1 by maize RNA-directed DNA methylation factor SHH2. J Integr Plant Biol, 63, 2021
|
|
7EF2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ef2 by Molmil](/molmil-images/mine/7ef2) | |
7EF3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ef3 by Molmil](/molmil-images/mine/7ef3) | |
7EF0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ef0 by Molmil](/molmil-images/mine/7ef0) | |
7DAD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dad by Molmil](/molmil-images/mine/7dad) | EPD in complex with tubulin | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Wang, Y, Wu, C. | Deposit date: | 2020-10-16 | Release date: | 2021-03-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | High-resolution X-ray structure of three microtubule-stabilizing agents in complex with tubulin provide a rationale for drug design. Biochem.Biophys.Res.Commun., 534, 2021
|
|
7ENR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7enr by Molmil](/molmil-images/mine/7enr) | |
7ENI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7eni by Molmil](/molmil-images/mine/7eni) | Crystal structure of cas and anti-cas protein complex | Descriptor: | AcrIIA13 protein, CRISPR-associated endonuclease Cas9, PHOSPHATE ION, ... | Authors: | Wang, Y, Li, X. | Deposit date: | 2021-04-17 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.632 Å) | Cite: | Crystal structure of cas and anti-cas protein complex To Be Published
|
|
7ENH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7enh by Molmil](/molmil-images/mine/7enh) | Crystal structure of cas and anti-cas protein complex | Descriptor: | AcrIIA14 protein, CRISPR-associated endonuclease Cas9, NICKEL (II) ION | Authors: | Wang, Y, Li, X. | Deposit date: | 2021-04-17 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Crystal structure of cas and anti-cas protein complex To Be Published
|
|
7ENM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7enm by Molmil](/molmil-images/mine/7enm) | |
2KKR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kkr by Molmil](/molmil-images/mine/2kkr) | Solution structure of SCA7 zinc finger domain from human ataxin-7 protein | Descriptor: | Ataxin-7, ZINC ION | Authors: | Wang, Y, Atkinson, A.R, Bonnet, J, Romier, C, Kieffer, B, Structural Proteomics in Europe (SPINE) | Deposit date: | 2009-06-29 | Release date: | 2010-06-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Histone deubiquitination by SAGA is modulated by an atypical zinc finger domain of Ataxin-7 To be Published
|
|
7DMZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dmz by Molmil](/molmil-images/mine/7dmz) | GMPCPP microtubule complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Wang, Y.X. | Deposit date: | 2020-12-08 | Release date: | 2021-12-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | GMPCPP microtubule complex To Be Published
|
|
7DN0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dn0 by Molmil](/molmil-images/mine/7dn0) | AJ-GMPCPP-MT-non-seam | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Wang, Y.X. | Deposit date: | 2020-12-08 | Release date: | 2021-12-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | GMPCPP microtubule To Be Published
|
|