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PDB: 1442 件

1CFB
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CRYSTAL STRUCTURE OF TANDEM TYPE III FIBRONECTIN DOMAINS FROM DROSOPHILA NEUROGLIAN AT 2.0 ANGSTROMS
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DROSOPHILA NEUROGLIAN, ...
著者Huber, A.H, Wang, Y.E, Bieber, A.J, Bjorkman, P.J.
登録日1994-08-27
公開日1994-11-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of tandem type III fibronectin domains from Drosophila neuroglian at 2.0 A.
Neuron, 12, 1994
7N6X
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Crystal structure of HIV-1 Protease multiple mutants PRS17 bound to inhibitor Amprenavir
分子名称: Protease, {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER
著者Burnaman, S.H, Wang, Y.-F, Weber, I.T.
登録日2021-06-09
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Revertant mutation V48G alters conformational dynamics of highly drug resistant HIV protease PRS17.
J.Mol.Graph.Model., 108, 2021
1ON9
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Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core (with hydrolyzed methylmalonyl-coenzyme a bound)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CADMIUM ION, METHYLMALONYL-COENZYME A, ...
著者Hall, P.R, Wang, Y.-F, Rivera-Hainaj, R.E, Zheng, X, Pustai-Carey, M, Carey, P.R, Yee, V.C.
登録日2003-02-27
公開日2003-05-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core
Embo J., 22, 2003
1F2E
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STRUCTURE OF SPHINGOMONAD, GLUTATHIONE S-TRANSFERASE COMPLEXED WITH GLUTATHIONE
分子名称: GLUTATHIONE, GLUTATHIONE S-TRANSFERASE
著者Nishio, T, Watanabe, T, Patel, A, Wang, Y, Lau, P.C.K, Grochulski, P, Li, Y, Cygler, M.
登録日2000-05-24
公開日2000-06-21
最終更新日2011-12-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Properties of a Sphingomonad and Marine Bacterium Beta-Class Glutathione S-Transferases and Crystal Structure of the Former Complex with Glutathione
To be published
1FF7
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THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII (FUCOSYLATED AT SER-60), NMR, 20 STRUCTURES
分子名称: PROTEIN (Blood Coagulation Factor VII), alpha-L-fucopyranose
著者Kao, Y.-H, Lee, G.F, Wang, Y, Starovasnik, M.A, Kelley, R.F, Spellman, M.W, Lerner, L.
登録日1999-02-19
公開日1999-06-16
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
5VEW
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Structure of the human GLP-1 receptor complex with PF-06372222
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Glucagon-like peptide 1 receptor,Endolysin chimera, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine, ...
著者Song, G, Yang, D, Wang, Y, Graaf, C.D, Zhou, Q, Jiang, S, Liu, K, Cai, X, Dai, A, Lin, G, Liu, D, Wu, F, Wu, Y, Zhao, S, Ye, L, Han, G.W, Lau, J, Wu, B, Hanson, M.A, Liu, Z.-J, Wang, M.-W, Stevens, R.C.
登録日2017-04-05
公開日2017-05-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.
Nature, 546, 2017
4DZD
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Crystal structure of the CRISPR-associated protein Cas6e from Escherichia coli str. K-12
分子名称: GLYCEROL, Uncharacterized protein ygcH
著者Wei, J, Huang, G, Wang, Y, Gong, W.
登録日2012-03-01
公開日2013-03-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Crystal Structure of endoribonuclease Cas6e from Escherichia coli
To be Published
8WQR
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Structure of the DDB1-AMBRA1 E3 ligase receptor complex linked to cell cycle regulation
分子名称: Activating molecule in BECN1-regulated autophagy protein 1, DNA damage-binding protein 1
著者Liu, M, Wang, Y, Su, M.Y, Stjepanovic, G.
登録日2023-10-12
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structure of the DDB1-AMBRA1 E3 ligase receptor complex linked to cell cycle regulation.
Nat Commun, 14, 2023
7KRJ
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The GR-Maturation Complex: Glucocorticoid Receptor in complex with Hsp90 and co-chaperone p23
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ...
著者Noddings, C.M, Wang, Y.-R, Agard, D.A.
登録日2020-11-20
公開日2022-01-12
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献Structure of Hsp90-p23-GR reveals the Hsp90 client-remodelling mechanism.
Nature, 601, 2021
6NOH
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Crystal structure of FBF-2 repeat 5 mutant (C363S, R364Y, Q367S) in complex with 8-nt RNA
分子名称: 1,2-ETHANEDIOL, Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*GP*UP*AP*AP*AP*UP*A)-3')
著者McCann, K.L, Wang, Y, Qiu, C, Hall, T.M.T.
登録日2019-01-16
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.249 Å)
主引用文献Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
6DJ7
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HIV-1 protease with mutation L76V in complex with GRL-5010 (gem-difluoro-bis-tetrahydrofuran as P2 ligand)
分子名称: (3R,3aS,6aS)-4,4-difluorohexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, ACETATE ION, CHLORIDE ION, ...
著者Wong-Sam, A.E, Wang, Y.F, Weber, I.T.
登録日2018-05-24
公開日2018-10-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Drug Resistance Mutation L76V Alters Nonpolar Interactions at the Flap-Core Interface of HIV-1 Protease.
ACS Omega, 3, 2018
6DXF
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BU of 6dxf by Molmil
Crystal structure of chalcone synthase from Selaginella moellendorffii - hydrogen peroxide treated
分子名称: Chalcone synthase
著者Liou, G, Chiang, Y.C, Wang, Y, Weng, J.K.
登録日2018-06-28
公開日2018-10-17
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants.
J. Biol. Chem., 293, 2018
6NOF
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Crystal structure of FBF-2 repeat 5 mutant (C363A, R364Y, Q367S) in complex with 8-nt RNA
分子名称: 1,2-ETHANEDIOL, Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*GP*UP*AP*AP*AP*UP*A)-3')
著者McCann, K.L, Wang, Y, Qiu, C, Hall, T.M.T.
登録日2019-01-16
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
5WQE
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Crystal structure of Alicyclobacillus acidoterrestris C2c1 in complex with single-guide RNA at 3.1 Angstrom resolution
分子名称: CRISPR-associated endonuclease C2c1, RNA (60-MER)
著者Liu, L, Wang, Y.L.
登録日2016-11-26
公開日2017-01-25
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3.126 Å)
主引用文献C2c1-sgRNA Complex Structure Reveals RNA-Guided DNA Cleavage Mechanism
Mol. Cell, 65, 2017
6DD2
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Crystal structure of Selaginella moellendorffii HCT
分子名称: Probable hydroxycinnamoyl transferase
著者Levsh, O, Chiang, Y.C, Lam, C.K, Wang, Y, Weng, J.K.
登録日2018-05-09
公開日2018-10-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9056 Å)
主引用文献Structural and dynamic basis of substrate permissiveness in hydroxycinnamoyltransferase (HCT).
PLoS Comput. Biol., 14, 2018
6DJ5
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HIV-1 protease with mutation L76V in complex with GRL-0519 (tris-tetrahydrofuran as P2 ligand)
分子名称: (3R,3aS,3bR,6aS,7aS)-octahydrodifuro[2,3-b:3',2'-d]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate, CHLORIDE ION, GLYCEROL, ...
著者Wong-Sam, A.E, Wang, Y.F, Weber, I.T.
登録日2018-05-24
公開日2018-10-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Drug Resistance Mutation L76V Alters Nonpolar Interactions at the Flap-Core Interface of HIV-1 Protease.
ACS Omega, 3, 2018
6DXD
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Crystal structure of chalcone synthase from Arabidopsis thaliana - C347S mutant
分子名称: Chalcone synthase
著者Liou, G, Chiang, Y.C, Wang, Y, Weng, J.K.
登録日2018-06-28
公開日2018-10-17
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants.
J. Biol. Chem., 293, 2018
6DXB
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Crystal structure of chalcone synthase from Arabidopsis thaliana
分子名称: Chalcone synthase
著者Liou, G, Chiang, Y.C, Wang, Y, Weng, J.K.
登録日2018-06-28
公開日2018-10-17
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (1.549 Å)
主引用文献Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants.
J. Biol. Chem., 293, 2018
1MOZ
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ADP-ribosylation factor-like 1 (ARL1) from Saccharomyces cerevisiae
分子名称: ADP-ribosylation factor-like protein 1, GUANOSINE-5'-DIPHOSPHATE
著者Amor, J.C, Horton, J.R, Zhu, X, Wang, Y, Sullards, C, Ringe, D, Cheng, X, Kahn, R.A.
登録日2002-09-10
公開日2002-10-09
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Structures of Yeast ARF2 and ARL1: DISTINCT ROLES FOR THE N TERMINUS IN THE STRUCTURE AND FUNCTION OF ARF FAMILY GTPases
J.Biol.Chem., 276, 2001
6DX9
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Crystal structure of chalcone synthase from Equisetum arvense
分子名称: Chalcone synthase
著者Weng, J.K, Liou, G, Chiang, Y.C, Wang, Y.
登録日2018-06-28
公開日2018-10-17
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants.
J. Biol. Chem., 293, 2018
6DXC
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Crystal structure of chalcone synthase from Selaginella moellendorffii - S340C mutant
分子名称: Chalcone synthase
著者Liou, G, Chiang, Y.C, Wang, Y, Weng, J.K.
登録日2018-06-28
公開日2018-10-17
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants.
J. Biol. Chem., 293, 2018
6NOC
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Crystal structure of FBF-2 repeat 5 mutant (C363A, R364Y) in complex with 8-nt RNA
分子名称: Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*GP*UP*AP*AP*AP*UP*A)-3')
著者McCann, K, Wang, Y, Qiu, C, Hall, T.M.T.
登録日2019-01-16
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.849 Å)
主引用文献Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
7VI6
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Crystal structure of GH3 beta-N-acetylhexosaminidase Amuc_2109 from Akkermansia muciniphila
分子名称: Beta-N-acetylhexosaminidase, CHLORIDE ION, MAGNESIUM ION
著者Qian, K, Yang, W, Chen, X, Wang, Y, Zhang, M, Wang, M.
登録日2021-09-26
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Functional and structural characterization of a GH3 beta-N-acetylhexosaminidase from Akkermansia muciniphila involved in mucin degradation
Biochem.Biophys.Res.Commun., 589, 2022
7VI7
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Crystal structure of GH3 beta-N-acetylhexosaminidase Amuc_2109 from Akkermansia muciniphila in complex with GlcNAc
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, Beta-N-acetylhexosaminidase, CHLORIDE ION, ...
著者Qian, K, Yang, W, Chen, X, Wang, Y, Zhang, M, Wang, M.
登録日2021-09-26
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Functional and structural characterization of a GH3 beta-N-acetylhexosaminidase from Akkermansia muciniphila involved in mucin degradation
Biochem.Biophys.Res.Commun., 589, 2022
6P7H
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Vaccine-elicited NHP FP-targeting neutralizing antibody DF2F-b.04 in complex with HIV fusion peptide (residue 512-519)
分子名称: Antibody DF2F-b.04 heavy chain, Antibody DF2F-b.04 light chain, HIV fusion peptide residues (512-519)
著者Xu, K, Liu, K, Wang, Y, Kwong, P.D.
登録日2019-06-05
公開日2020-06-10
実験手法X-RAY DIFFRACTION (1.782 Å)
主引用文献Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies
To Be Published

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