5WQE
Crystal structure of Alicyclobacillus acidoterrestris C2c1 in complex with single-guide RNA at 3.1 Angstrom resolution
Summary for 5WQE
| Entry DOI | 10.2210/pdb5wqe/pdb |
| Descriptor | CRISPR-associated endonuclease C2c1, RNA (60-MER) (3 entities in total) |
| Functional Keywords | crispr-cas endonuclease, recognition lobe, nuclease lobe, rna binding protein |
| Biological source | Alicyclobacillus acidoterrestris More |
| Total number of polymer chains | 2 |
| Total formula weight | 169244.82 |
| Authors | Liu, L.,Wang, Y.L. (deposition date: 2016-11-26, release date: 2017-01-25, Last modification date: 2017-10-18) |
| Primary citation | Liu, L.,Chen, P.,Wang, M.,Li, X.,Wang, J.,Yin, M.,Wang, Y. C2c1-sgRNA Complex Structure Reveals RNA-Guided DNA Cleavage Mechanism Mol. Cell, 65:310-322, 2017 Cited by PubMed: 27989439DOI: 10.1016/j.molcel.2016.11.040 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.126 Å) |
Structure validation
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