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PDB: 481 results

6U5Y
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Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Descriptor: 3-{[(5-bromo-3-chloro-2-hydroxyphenyl)sulfonyl]amino}-5-(1-cyanocyclobutyl)-2-hydroxy-N-methylbenzamide, WD repeat-containing protein 5
Authors:Zhao, B, Wang, F.
Deposit date:2019-08-28
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.532 Å)
Cite:Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
6U5M
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Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Descriptor: 5-bromo-2-hydroxy-N-[3-(methylsulfonyl)-5-(pentafluoro-lambda~6~-sulfanyl)phenyl]benzene-1-sulfonamide, WD repeat-containing protein 5
Authors:Zhao, B, Wang, F.
Deposit date:2019-08-28
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
6U6W
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BU of 6u6w by Molmil
Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Descriptor: 5-bromo-N-(5-chloro-2-hydroxyphenyl)-2-methoxybenzene-1-sulfonamide, WD repeat-containing protein 5
Authors:Zhao, B, Wang, F.
Deposit date:2019-08-30
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
6U8O
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BU of 6u8o by Molmil
Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Descriptor: 5-bromo-N-[5-(1-cyanocyclobutyl)-2-hydroxyphenyl]-2-hydroxybenzene-1-sulfonamide, WD repeat-containing protein 5
Authors:Zhao, B, Wang, F.
Deposit date:2019-09-05
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
8FQC
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BU of 8fqc by Molmil
Structure of baseplate with receptor binding complex of Agrobacterium phage Milano
Descriptor: Baseplate Centerpiece, gp25, Baseplate Central Spike, ...
Authors:Sonani, R.R, Leiman, P.G, Wang, F, Kreutzberger, M.A.B, Sebastian, A, Esteves, N.C, Kelly, R.J, Scharf, B, Egelman, E.H.
Deposit date:2023-01-05
Release date:2024-01-31
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:An extensive disulfide bond network prevents tail contraction in Agrobacterium tumefaciens phage Milano.
Nat Commun, 15, 2024
6U80
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BU of 6u80 by Molmil
Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Descriptor: 5-bromo-N-(4-hydroxy[1,1'-biphenyl]-3-yl)-2-methoxybenzene-1-sulfonamide, WD repeat-containing protein 5
Authors:Zhao, B, Wang, F.
Deposit date:2019-09-04
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
8GAE
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BU of 8gae by Molmil
Hsp90 provides platform for CRaf dephosphorylation by PP5
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ...
Authors:Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A.
Deposit date:2023-02-22
Release date:2023-04-26
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Hsp90 provides a platform for kinase dephosphorylation by PP5.
Nat Commun, 14, 2023
6K6L
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BU of 6k6l by Molmil
YGL082W-catalytic domain
Descriptor: pseudo deubiquitinase
Authors:Lu, L.N, Wang, F.
Deposit date:2019-06-03
Release date:2019-07-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Inactivity of YGL082W in vitro due to impairment of conformational change in the catalytic center loop
Sci China Chem, 2019
4ZMI
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BU of 4zmi by Molmil
Crystal structure of the Helical domain of S. pombe Taz1
Descriptor: COBALT (II) ION, MAGNESIUM ION, Telomere length regulator taz1
Authors:Deng, W, Wu, J, Wang, F, Lei, M.
Deposit date:2015-05-04
Release date:2015-09-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2.
Cell Res., 25, 2015
3K5M
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BU of 3k5m by Molmil
Crystal structure of E.coli Pol II-abasic DNA-ddGTP Lt(-2, 2) ternary complex
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*TP*GP*(3DR)P*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-07
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
4ZWV
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BU of 4zwv by Molmil
Crystal Structure of Aminotransferase AtmS13 from Actinomadura melliaura
Descriptor: GLYCEROL, Putative aminotransferase
Authors:Kim, Y, Bigelow, L, Endres, M, Wang, F, Phillips Jr, G.N, Joachimiak, A, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2015-05-19
Release date:2015-06-03
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.503 Å)
Cite:Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis.
Proteins, 83, 2015
3J3T
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BU of 3j3t by Molmil
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
Descriptor: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
4ZMK
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BU of 4zmk by Molmil
Crystal structure of the dimerization domain of S. pombe Taz1
Descriptor: Telomere length regulator taz1
Authors:Deng, W, Wu, J, Wang, F, Lei, M.
Deposit date:2015-05-04
Release date:2015-09-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2.
Cell Res., 25, 2015
3J3R
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BU of 3j3r by Molmil
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
Descriptor: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine
J.Biol.Chem., 288, 2013
3K59
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BU of 3k59 by Molmil
Crystal structure of E.coli Pol II-normal DNA-dCTP ternary complex
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*GP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
3K5N
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BU of 3k5n by Molmil
Crystal structure of E.coli Pol II-abasic DNA binary complex
Descriptor: DNA (5'-D(*GP*TP*CP*CP*TP*GP*(3DR)*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*G)-3'), DNA polymerase II
Authors:Yang, W, Wang, F.
Deposit date:2009-10-07
Release date:2010-02-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
3K57
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BU of 3k57 by Molmil
Crystal structure of E.coli Pol II-normal DNA-dATP ternary complex
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*G*TP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*G)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
3JCI
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BU of 3jci by Molmil
2.9 Angstrom Resolution Cryo-EM 3-D Reconstruction of Close-packed PCV2 Virus-like Particles
Descriptor: Capsid protein
Authors:Liu, Z, Guo, F, Wang, F, Li, T.C, Jiang, W.
Deposit date:2015-12-13
Release date:2016-02-03
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:2.9 angstrom Resolution Cryo-EM 3D Reconstruction of Close-Packed Virus Particles.
Structure, 24, 2016
3K58
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BU of 3k58 by Molmil
Crystal structure of E.coli Pol II-normal DNA-dTTP ternary complex
Descriptor: DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*AP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA polymerase II, ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
3K5L
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BU of 3k5l by Molmil
Crystal structure of E.coli Pol II-abasic DNA-dATP Lt(0, 3) ternary complex
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*TP*(3DR)P*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-07
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
3J3S
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BU of 3j3s by Molmil
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
Descriptor: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J3U
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BU of 3j3u by Molmil
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
Descriptor: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3JCP
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BU of 3jcp by Molmil
Structure of yeast 26S proteasome in M2 state derived from Titan dataset
Descriptor: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
Authors:Luan, B, Huang, X.L, Wu, J.P, Shi, Y.G, Wang, F.
Deposit date:2016-01-06
Release date:2016-06-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of an endogenous yeast 26S proteasome reveals two major conformational states.
Proc.Natl.Acad.Sci.USA, 113, 2016
3MAQ
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BU of 3maq by Molmil
Crystal structure of E.coli Pol II-normal DNA-dGTP ternary complex
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*CP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2010-03-24
Release date:2010-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
4Y2I
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Gold ion bound to GolB
Descriptor: GOLD ION, Putative metal-binding transport protein
Authors:Wei, W, Wang, F, Ma, L, Zhao, J.
Deposit date:2015-02-10
Release date:2016-02-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015

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PDB entries from 2024-11-06

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