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PDB: 13131 results

8G0X
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BU of 8g0x by Molmil
Backbone modifications in the inter-helix loop of designed miniprotein oPPalpha: Pro10DPro11 turn
Descriptor: Designed miniprotein oPPalpha: Pro10DPro11 turn
Authors:Harmon, T.W, Horne, W.S.
Deposit date:2023-02-01
Release date:2023-04-05
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Protein Backbone Alteration in Non-Hairpin beta-Turns: Impacts on Tertiary Folded Structure and Folded Stability.
Chembiochem, 24, 2023
4Q2W
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BU of 4q2w by Molmil
Crystal Structure of pneumococcal peptidoglycan hydrolase LytB
Descriptor: GLYCEROL, Putative endo-beta-N-acetylglucosaminidase
Authors:Bai, X.H, Chen, H.J, Jiang, Y.L, Wen, Z, Cheng, W, Li, Q, Zhang, J.R, Chen, Y, Zhou, C.Z.
Deposit date:2014-04-10
Release date:2014-07-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of pneumococcal peptidoglycan hydrolase LytB reveals insights into the bacterial cell wall remodeling and pathogenesis.
J.Biol.Chem., 289, 2014
2NA9
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BU of 2na9 by Molmil
Transmembrane Structure of the P441A Mutant of the Cytokine Receptor Common Subunit beta
Descriptor: Cytokine receptor common subunit beta
Authors:Schmidt, T, Ye, F, Situ, A.J, An, W, Ginsberg, M.H, Ulmer, T.S.
Deposit date:2015-12-21
Release date:2016-07-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A Conserved Ectodomain-Transmembrane Domain Linker Motif Tunes the Allosteric Regulation of Cell Surface Receptors.
J.Biol.Chem., 291, 2016
6A82
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BU of 6a82 by Molmil
Crystal structure of the C-terminal periplasmic domain of EcEptC from Escherichia coli
Descriptor: Phosphoethanolamine transferase EptC, SODIUM ION
Authors:Zhao, Y.Q, Gu, Y.J, Cheng, W.
Deposit date:2018-07-06
Release date:2018-12-26
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and mechanistic insights into polymyxin resistance mediated by EptC originating from Escherichia coli.
FEBS J., 286, 2019
3IYG
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BU of 3iyg by Molmil
Ca model of bovine TRiC/CCT derived from a 4.0 Angstrom cryo-EM map
Descriptor: T-complex protein 1 subunit, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
Authors:Cong, Y, Baker, M.L, Ludtke, S.J, Frydman, J, Chiu, W.
Deposit date:2009-11-28
Release date:2010-03-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4 Å)
Cite:4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement.
Proc.Natl.Acad.Sci.USA, 107, 2010
6I66
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BU of 6i66 by Molmil
Crystal structure of human ERRg LBD in complex with 4-sec-butylphenol
Descriptor: 4-[(2~{R})-butan-2-yl]phenol, Estrogen-related receptor gamma, GLYCEROL
Authors:Delfosse, V, Blanc, P, Bourguet, W.
Deposit date:2018-11-15
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Insights into the activation mechanism of human estrogen-related receptor gamma by environmental endocrine disruptors.
Cell.Mol.Life Sci., 76, 2019
6ACC
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BU of 6acc by Molmil
Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-free conformation with three RBD in down conformation
Descriptor: Spike glycoprotein
Authors:Gui, M, Song, W.
Deposit date:2018-07-26
Release date:2018-08-08
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2.
PLoS Pathog., 14, 2018
3IZH
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BU of 3izh by Molmil
Mm-cpn D386A with ATP
Descriptor: Chaperonin
Authors:Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J.
Deposit date:2010-10-29
Release date:2011-02-02
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber.
Cell(Cambridge,Mass.), 144, 2011
1CMC
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BU of 1cmc by Molmil
THREE DIMENSIONAL CRYSTAL STRUCTURES OF E. COLI MET REPRESSOR WITH AND WITHOUT COREPRESSOR
Descriptor: MAGNESIUM ION, MET REPRESSOR, S-ADENOSYLMETHIONINE
Authors:Somers, W.S, Phillips, S.E.V.
Deposit date:1992-08-28
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three-dimensional crystal structures of Escherichia coli met repressor with and without corepressor.
Nature, 341, 1989
3J0C
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BU of 3j0c by Molmil
Models of E1, E2 and CP of Venezuelan Equine Encephalitis Virus TC-83 strain restrained by a near atomic resolution cryo-EM map
Descriptor: Capsid protein, E1 envelope glycoprotein, E2 envelope glycoprotein
Authors:Zhang, R, Hryc, C.F, Cong, Y, Liu, X, Jakana, J, Gorchakov, R, Baker, M.L, Weaver, S.C, Chiu, W.
Deposit date:2011-06-22
Release date:2011-08-24
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:4.4 A cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus.
Embo J., 30, 2011
3IYF
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BU of 3iyf by Molmil
Atomic Model of the Lidless Mm-cpn in the Open State
Descriptor: Chaperonin
Authors:Zhang, J, Baker, M.L, Schroeder, G, Douglas, N.R, Reissmann, S, Jakana, J, Dougherty, M, Fu, C.J, Levitt, M, Ludtke, S.J, Frydman, J, Chiu, W.
Deposit date:2009-10-23
Release date:2010-02-02
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Mechanism of folding chamber closure in a group II chaperonin
Nature, 463, 2010
4QGE
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BU of 4qge by Molmil
phosphodiesterase-9A in complex with inhibitor WYQ-C36D
Descriptor: MAGNESIUM ION, N~2~-(1-cyclopentyl-4-oxo-4,7-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-N-(4-methoxyphenyl)-D-alaninamide, Phosphodiesterase 9A, ...
Authors:Shao, Y.-X, Huang, M, Cui, W, Ke, H.
Deposit date:2014-05-22
Release date:2014-12-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of a Phosphodiesterase 9A Inhibitor as a Potential Hypoglycemic Agent.
J.Med.Chem., 57, 2014
3IZM
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BU of 3izm by Molmil
Mm-cpn wildtype with ATP
Descriptor: Chaperonin
Authors:Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J.
Deposit date:2010-10-30
Release date:2011-02-02
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber.
Cell(Cambridge,Mass.), 144, 2011
6ACD
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BU of 6acd by Molmil
Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-free conformation with one RBD in up conformation
Descriptor: Spike glycoprotein
Authors:Gui, M, Song, W.
Deposit date:2018-07-26
Release date:2018-08-08
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2.
PLoS Pathog., 14, 2018
3IZL
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BU of 3izl by Molmil
Mm-cpn rls deltalid with ATP and AlFx
Descriptor: Mm-cpn rls deltalid
Authors:Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J.
Deposit date:2010-10-29
Release date:2011-02-02
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber.
Cell(Cambridge,Mass.), 144, 2011
3IZP
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BU of 3izp by Molmil
Conformation of EF-G during translocation
Descriptor: Elongation factor G
Authors:Li, W, Trabuco, L.G, Schulten, K, Frank, J.
Deposit date:2010-11-15
Release date:2011-03-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY
Cite:Molecular dynamics of EF-G during translocation.
Proteins, 79, 2011
3IZN
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BU of 3izn by Molmil
Mm-cpn deltalid with ATP
Descriptor: Chaperonin
Authors:Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J.
Deposit date:2010-10-30
Release date:2011-02-02
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber.
Cell(Cambridge,Mass.), 144, 2011
2N7K
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BU of 2n7k by Molmil
Unveiling the structural determinants of KIAA0323 binding preference for NEDD8
Descriptor: NEDD8, Protein KHNYN
Authors:Santonico, E, Nepravishta, R, Mattioni, A, Valentini, E, Mandaliti, W, Procopio, R, Iannuccelli, M, Castagnoli, L, Polo, S, Paci, M, Cesareni, G.
Deposit date:2015-09-14
Release date:2016-09-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Unveiling the structural determinants of KIAA0323 binding preference for NEDD8
To be Published
3J0F
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BU of 3j0f by Molmil
Sindbis virion
Descriptor: Capsid protein, E1 envelope glycoprotein, E2 envelope glycoprotein
Authors:Tang, J, Jose, J, Zhang, W, Chipman, P, Kuhn, R.J, Baker, T.S.
Deposit date:2011-07-08
Release date:2011-10-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Molecular Links between the E2 Envelope Glycoprotein and Nucleocapsid Core in Sindbis Virus.
J.Mol.Biol., 414, 2011
3IZK
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BU of 3izk by Molmil
Mm-cpn rls deltalid with ATP
Descriptor: Chaperonin
Authors:Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J.
Deposit date:2010-10-29
Release date:2011-02-02
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber.
Cell(Cambridge,Mass.), 144, 2011
4QP3
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BU of 4qp3 by Molmil
Crystal Structure of ERK2 in complex with (S)-2-((9H-purin-6-yl)amino)-3-phenylpropan-1-ol
Descriptor: (2S)-3-phenyl-2-(9H-purin-6-ylamino)propan-1-ol, Mitogen-activated protein kinase 1
Authors:Yin, J, Wang, W.
Deposit date:2014-06-22
Release date:2015-09-23
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (2.599 Å)
Cite:Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
4QE9
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BU of 4qe9 by Molmil
Open MthK pore structure soaked in 10 mM Ba2+/100 mM K+
Descriptor: Calcium-gated potassium channel MthK, POTASSIUM ION
Authors:Guo, R, Zeng, W, Cui, H, Chen, L, Ye, S.
Deposit date:2014-05-15
Release date:2014-07-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Ionic interactions of Ba2+ blockades in the MthK K+ channel
J.Gen.Physiol., 144, 2014
4QZ1
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BU of 4qz1 by Molmil
yCP beta5-M45T mutant in complex with the epoxyketone inhibitor ONX 0914
Descriptor: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Huber, E.M, Heinemeyer, W, Groll, M.
Deposit date:2014-07-27
Release date:2015-02-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
2NB7
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BU of 2nb7 by Molmil
Solution structure of N-terminal extramembrane domain of SH protein
Descriptor: Small hydrophobic protein
Authors:Li, Y, To, J, Surya, W, Torres, J.
Deposit date:2016-01-26
Release date:2016-02-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Inhibition of the human respiratory syncytial virus small hydrophobic protein and structural variations in a bicelle environment.
J.Virol., 88, 2014
4QZZ
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BU of 4qzz by Molmil
yCP in complex with Omuralide
Descriptor: CHLORIDE ION, MAGNESIUM ION, Omuralide, ...
Authors:Huber, E.M, Heinemeyer, W, Groll, M.
Deposit date:2014-07-29
Release date:2015-02-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015

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數據於2024-11-13公開中

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