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PDB: 12889 件

8CGF
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Interleukin-4 (wild type) pH 2.4
分子名称: Interleukin-4
著者Vaz, D.C, Rodrigues, J.R, Loureiro-Ferreira, N, Mueller, T, Sebald, W, Redfield, C, Brito, R.M.M.
登録日2023-02-04
公開日2023-10-18
最終更新日2024-01-17
実験手法SOLUTION NMR
主引用文献Lessons on protein structure from interleukin-4: All disulfides are not created equal.
Proteins, 92, 2024
7OI3
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Cryo-EM structure of the Cetacean morbillivirus nucleoprotein-RNA complex
分子名称: Cetacean morbillivirus nucleoprotein, poly-A 6-mer
著者Zinzula, L, Beck, F, Klumpe, S, Bohn, S, Pfeifer, G, Bollschweiler, D, Nagy, I, Plitzko, J.M, Baumeister, W.
登録日2021-05-11
公開日2021-06-23
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structure of the cetacean morbillivirus nucleoprotein-RNA complex.
J.Struct.Biol., 213, 2021
7O12
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ABC transporter NosDFY, AMPPNP-bound in GDN
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Probable ABC transporter ATP-binding protein NosF, ...
著者Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J.
登録日2021-03-28
公開日2022-04-13
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
7O11
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ABC transporter NosDFY, nucleotide-free in GDN, R-domain 1
分子名称: MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ...
著者Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J.
登録日2021-03-28
公開日2022-04-13
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
7O2U
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PqsR (MvfR) in complex with antagonist 40
分子名称: 2-[4-[(2S)-3-(6-chloranyl-4-oxidanylidene-quinazolin-3-yl)-2-oxidanyl-propoxy]phenoxy]ethanenitrile, LysR family transcriptional regulator
著者Emsley, J, Richardson, W.
登録日2021-03-31
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献PqsR (MvfR) in complex with antagonist 40
To Be Published
7O10
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ABC transporter NosDFY, nucleotide-free in GDN, R-domain 2
分子名称: MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ...
著者Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J.
登録日2021-03-28
公開日2022-04-13
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
7O17
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ABC transporter NosDFY E154Q, ATP-bound in lipid nanodisc
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, ...
著者Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J.
登録日2021-03-28
公開日2022-04-13
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
7O2T
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PqsR (MvfR) in complex with antagonist 61
分子名称: 2-[4-[(2S)-3-(6-chloro-4-oxoquinazolin-3-yl)-2-hydroxypropoxy]phenyl]acetonitrile, LysR family transcriptional regulator
著者Emsley, J, Richardson, W.
登録日2021-03-31
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献PqsR (MvfR) in complex with antagonist 61
To Be Published
8CBA
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Crystal structure of N-terminal domain of TraF, protein of a type IV secretion system from E.faecalis (pIP501)
分子名称: Conjugal transfer protein traF
著者Berger, T.M.I, Stallinger, A, Pavkov-Keller, T, Keller, W.
登録日2023-01-25
公開日2024-02-07
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal structure of N-terminal domain of TraF, protein of a type IV secretion system from E.faecalis (pIP501)
to be published
8CCT
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Crystal structure of the human PXR ligand-binding domain in complex with 2,2'-dichloro bisphenol A
分子名称: 2-chloranyl-4-[2-(3-chloranyl-4-oxidanyl-phenyl)propan-2-yl]phenol, Nuclear receptor subfamily 1 group I member 2
著者Derosa, Q, Grimaldi, M, Carivenc, C, Boulahtouf, A, Bourguet, W, Balaguer, P.
登録日2023-01-27
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the hPXR-LBD in complex with 2,2'-dichloro bisphenol A
To Be Published
7OC3
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Crystal structure of the third tudor domain of Qin
分子名称: PHOSPHATE ION, Qin
著者Dhimole, N, Klug, W, Carlomagno, T.
登録日2021-04-25
公開日2022-05-04
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of the third tudor domain of Qin
To Be Published
1KLK
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CRYSTAL STRUCTURE OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE TERNARY COMPLEX WITH PT653 AND NADPH
分子名称: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE
著者Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Rosowsky, A, Queener, S.F.
登録日2001-12-12
公開日2002-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH.
Acta Crystallogr.,Sect.D, 58, 2002
8CMZ
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BU of 8cmz by Molmil
Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with Coenzyme A
分子名称: COENZYME A, ZINC ION, histone acetyltransferase
著者Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F.
登録日2023-02-21
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.252 Å)
主引用文献Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with Coenzyme A
To Be Published
8CN0
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Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with Coenzyme A
分子名称: COENZYME A, ZINC ION, histone acetyltransferase
著者Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F.
登録日2023-02-21
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with Coenzyme A
To Be Published
8CNA
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Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA
分子名称: ZINC ION, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate, histone acetyltransferase
著者Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F.
登録日2023-02-22
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.463 Å)
主引用文献Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA
To Be Published
8IDS
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BU of 8ids by Molmil
Crystal structure of Bacillus sp. AHU2216 GH13_31 Alpha-glucosidase E256Q/N258P in complex with maltotriose
分子名称: Alpha-glucosidase, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Auiewiriyanukul, W, Saburi, W, Yu, J, Kato, K, Yao, M, Mori, H.
登録日2023-02-14
公開日2023-05-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Alteration of Substrate Specificity and Transglucosylation Activity of GH13_31 alpha-Glucosidase from Bacillus sp. AHU2216 through Site-Directed Mutagenesis of Asn258 on beta → alpha Loop 5.
Molecules, 28, 2023
8CNC
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Structure of compound 1 bound KMT9
分子名称: 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl)amino}-5'-deoxyadenosine, Methyltransferase N6AMT1, Multifunctional methyltransferase subunit TRM112-like protein
著者Sheng, W.
登録日2023-02-22
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structure of compound 1 bound KMT9
To Be Published
8CND
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Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA
分子名称: ZINC ION, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate, histone acetyltransferase
著者Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F.
登録日2023-02-22
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.972 Å)
主引用文献Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA
To Be Published
8CNB
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Crystal structure of CREBBP-Y1503C histone acetyltransferase domain in complex with Coenzyme A
分子名称: COENZYME A, ZINC ION, histone acetyltransferase
著者Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F.
登録日2023-02-22
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.986 Å)
主引用文献Crystal structure of CREBBP-Y1503C histone acetyltransferase domain in complex with Coenzyme A
To Be Published
5DG4
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BU of 5dg4 by Molmil
Crystal structure of monomer human cellular retinol binding protein II-Y60L
分子名称: ACETATE ION, Retinol-binding protein 2
著者Assar, Z, Nossoni, Z, Wang, W, Gieger, J.H, Borhan, B.
登録日2015-08-27
公開日2016-09-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates.
Structure, 24, 2016
4AIT
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BU of 4ait by Molmil
RESTRAINED ENERGY REFINEMENT WITH TWO DIFFERENT ALGORITHMS AND FORCE FIELDS OF THE STRUCTURE OF THE ALPHA-AMYLASE INHIBITOR TENDAMISTAT DETERMINED BY NMR IN SOLUTION
分子名称: TENDAMISTAT
著者Billeter, M, Schaumann, T, Braun, W, Wuthrich, K.
登録日1990-05-14
公開日1991-04-15
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Restrained Energy Refinement with Two Different Algorithms and Force Fields of the Structure of the Alpha-Amylase Inhibitor Tendamistat Determined by NMR in Solution
Biopolymers, 29, 1990
2AN7
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BU of 2an7 by Molmil
Solution structure of the bacterial antidote ParD
分子名称: Protein parD
著者Oberer, M, Zangger, K, Gruber, K, Keller, W.
登録日2005-08-11
公開日2006-09-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The solution structure of ParD, the antidote of the ParDE toxin antitoxin module, provides the structural basis for DNA and toxin binding.
Protein Sci., 16, 2007
1AQJ
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BU of 1aqj by Molmil
STRUCTURE OF ADENINE-N6-DNA-METHYLTRANSFERASE TAQI
分子名称: ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, SINEFUNGIN
著者Schluckebier, G, Saenger, W.
登録日1996-07-25
公開日1997-02-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
8CNM
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Human Sirt6 in complex with the inhibitor S6020 and ADP-ribose
分子名称: 1,2-ETHANEDIOL, 4-azanyl-~{N}-(4-oxidanylcyclohexyl)benzenesulfonamide, CHLORIDE ION, ...
著者You, W, Steegborn, C.
登録日2023-02-23
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8CNO
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Improved complex structure of human Sirtuin 6 with its inhibitor cis-resveratrol
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者You, W, Steegborn, C.
登録日2023-02-23
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published

222036

件を2024-07-03に公開中

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