8CCT

Crystal structure of the human PXR ligand-binding domain in complex with 2,2'-dichloro bisphenol A

Summary for 8CCT

• Entry DOI: 10.2210/pdb8cct/pdb
• Descriptor: Nuclear receptor subfamily 1 group I member 2, 2-chloranyl-4-[2-(3-chloranyl-4-oxidanyl-phenyl)propan-2-yl]phenol (3 entities in total)
• Functional Keywords: nuclear receptor, hormone receptor, pregnane x receptor, nuclear protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37341.82

Authors

Derosa, Q.,Grimaldi, M.,Carivenc, C.,Boulahtouf, A.,Bourguet, W.,Balaguer, P. (deposition date: 2023-01-27, release date: 2024-02-07)

• Primary citation: Derosa, Q.,Grimaldi, M.,Carivenc, C.,Boulahtouf, A.,Bourguet, W.,Balaguer, P.; Crystal structure of the hPXR-LBD in complex with 2,2'-dichloro bisphenol A; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.9 Å)