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PDB: 12929 件

4C1R
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Bacteroides thetaiotaomicron VPI-5482 mannosyl-6-phosphatase Bt3783
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, MANNOSYL-6-PHOSPHATASE
著者Cuskin, F, Lowe, E.C, Zhu, Y, Temple, M, Thompson, A.J, Cartmell, A, Piens, K, Bracke, D, Vervecken, W, Munoz-Munoz, J.L, Suits, M.D.L, Boraston, A.B, Williams, S.J, Davies, G.J, Abbott, W.D, Martens, E.C, Gilbert, H.J.
登録日2013-08-13
公開日2013-11-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human Gut Bacteroidetes Can Utilize Yeast Mannan Through a Selfish Mechanism.
Nature, 517, 2015
1P5A
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Conformational Mapping of the N-terminal Peptide of HIV-1 GP41 in lipid detergent and aqueous environments using 13C-enhanced Fourier Transform Infrared Spectroscopy
分子名称: Envelope polyprotein GP160
著者Gordon, L.M, Mobley, P.W, Lee, W, Eskandari, S, Kaznessis, Y.N, Sherman, M.A, Waring, A.J.
登録日2003-04-25
公開日2003-05-20
最終更新日2011-07-13
実験手法INFRARED SPECTROSCOPY
主引用文献Conformational mapping of the N-terminal peptide of HIV-1 gp41 in lipid detergent and aqueous environments using 13C-enhanced Fourier transform infrared spectroscopy.
Protein Sci., 13, 2004
1OU6
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Biosynthetic thiolase from Zoogloea ramigera in complex with acetyl-O-pantetheine-11-pivalate
分子名称: Acetyl-CoA acetyltransferase, PANTOTHENYL-AMINOETHANOL-ACETATE PIVALIC ACID, SULFATE ION
著者Kursula, P, Schmitz, W, Wierenga, R.K.
登録日2003-03-24
公開日2004-06-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The surprising binding mode of a coenzyme A analogue, O-pantetheine-11-pivalate, in the catalytic cavity of bacterial biosynthetic thiolase
To be Published
1OWJ
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Substituted 2-Naphthamidine Inhibitors of Urokinase
分子名称: 6-[(Z)-AMINO(IMINO)METHYL]-N-(1-ISOPROPYL-3,4-DIHYDROISOQUINOLIN-7-YL)-2-NAPHTHAMIDE, Urokinase-type plasminogen activator
著者Wendt, M.D, Rockway, T.W, Geyer, A, McClellan, W, Weitzberg, M, Zhao, X, Mantei, R, Nienaber, V.L, Stewart, K, Klinghofer, V, Giranda, V.L.
登録日2003-03-28
公開日2003-09-30
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution.
J.Med.Chem., 47, 2004
4C5U
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BU of 4c5u by Molmil
Structural Investigations into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus chinensis
分子名称: PHENYLALANINE AMMONIA-LYASE
著者Wybenga, G.G, Szymanski, W, Wu, B, Feringa, B.L, Janssen, D.B, Dijkstra, B.W.
登録日2013-09-16
公開日2014-05-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural Investigations Into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus Chinensis.
Biochemistry, 53, 2014
4QP6
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Crystal Structure of ERK2 in complex with 5H-pyrrolo[2,3-b]pyrazine
分子名称: 5H-pyrrolo[2,3-b]pyrazine, IMIDAZOLE, Mitogen-activated protein kinase 1
著者Yin, J, Wang, W.
登録日2014-06-22
公開日2015-09-23
最終更新日2015-12-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
1OP4
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Solution Structure of Neural Cadherin Prodomain
分子名称: Neural-cadherin
著者Koch, A.W, Farooq, A, Shan, W, Zeng, L, Colman, D.R, Zhou, M.-M.
登録日2003-03-04
公開日2004-03-16
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Structure of the Neural (N-) Cadherin Prodomain Reveals a Cadherin Extracellular Domain-like Fold without Adhesive Characteristics
Structure, 12, 2004
4QGN
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Human acireductone dioxygenase with iron ion and L-methionine in active center
分子名称: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, ACETATE ION, CHLORIDE ION, ...
著者Milaczewska, A.M, Chruszcz, M, Petkowski, J.J, Niedzialkowska, E, Minor, W, Borowski, T.
登録日2014-05-23
公開日2015-05-27
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献On the Structure and Reaction Mechanism of Human Acireductone Dioxygenase.
Chemistry, 24, 2018
4BBA
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Crystal structure of glucokinase regulatory protein complexed to phosphate
分子名称: GLUCOKINASE REGULATORY PROTEIN, PHOSPHATE ION
著者Pautsch, A, Stadler, N, Loehle, A, Lenter, M, Rist, W, Berg, A, Glocker, L, Nar, H, Reinhart, D, Heckel, A, Schnapp, G, Kauschke, S.G.
登録日2012-09-21
公開日2013-05-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystal Structure of Glucokinase Regulatory Protein.
Biochemistry, 52, 2013
1P1E
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Structural Insights into the Inter-domain Chaperoning of Tandem PDZ Domains in Glutamate Receptor Interacting Proteins
分子名称: Glutamate receptor interacting protein
著者Feng, W, Shi, Y, Li, M, Zhang, M.
登録日2003-04-12
公開日2003-11-11
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding
Nat.Struct.Biol., 10, 2003
1Q2K
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BU of 1q2k by Molmil
Solution structure of BmBKTx1 a new potassium channel blocker from the Chinese Scorpion Buthus martensi Karsch
分子名称: Neurotoxin BmK37
著者Cai, Z, Xu, C, Xu, Y, Lu, W, Chi, C.W, Shi, Y, Wu, J.
登録日2003-07-25
公開日2003-09-09
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution Structure of BmBKTx1, a New BK(Ca)(1) Channel Blocker from the Chinese Scorpion Buthus martensi Karsch(,).
Biochemistry, 43, 2004
3ROG
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BU of 3rog by Molmil
Crystal Structure of Mouse Apolipoprotein A-I Binding Protein in Complex with Thymidine 3'-monophosphate
分子名称: Apolipoprotein A-I-binding protein, SULFATE ION, THYMIDINE-3'-PHOSPHATE
著者Shumilin, I.A, Jha, K.N, Cymborowski, M, Herr, J.C, Minor, W.
登録日2011-04-25
公開日2012-07-18
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012
3RGZ
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Structural insight into brassinosteroid perception by BRI1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chai, J, Han, Z, She, J, Wang, J, Cheng, W.
登録日2011-04-11
公開日2011-06-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.281 Å)
主引用文献Structural insight into brassinosteroid perception by BRI1.
Nature, 474, 2011
4QP8
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Crystal Structure of ERK2 in complex with 2-(1H-pyrazol-4-yl)-7-(pyridin-3-yl)-5H-pyrrolo[2,3-b]pyrazine
分子名称: 2-(1H-pyrazol-4-yl)-7-(pyridin-3-yl)-5H-pyrrolo[2,3-b]pyrazine, Mitogen-activated protein kinase 1
著者Yin, J, Wang, W.
登録日2014-06-22
公開日2015-09-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.446 Å)
主引用文献Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
3RQQ
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Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis in complex with P1,P3-Di(adenosine-5') triphosphate
分子名称: ADP/ATP-DEPENDENT NAD(P)H-HYDRATE DEHYDRATASE, BIS(ADENOSINE)-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Shumilin, I.A, Cymborowski, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2011-04-28
公開日2011-07-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012
1Q5T
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BU of 1q5t by Molmil
Gln48 PLA2 separated from Vipoxin from the venom of Vipera ammodytes meridionalis.
分子名称: Phospholipase A2 inhibitor, SULFATE ION
著者Georgieva, D.N, Perbandt, M, Rypniewski, W, Hristov, K, Genov, N, Betzel, C.
登録日2003-08-11
公開日2004-05-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The X-ray structure of a snake venom Gln48 phospholipase A2 at 1.9A resolution reveals anion-binding sites.
Biochem.Biophys.Res.Commun., 316, 2004
3RS8
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Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima in complex with ADP-ribose
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, GLYCEROL, MAGNESIUM ION, ...
著者Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W.
登録日2011-05-02
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012
3RTE
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BU of 3rte by Molmil
Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with NADP and ATP.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W.
登録日2011-05-03
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012
4AYC
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RNF8 RING domain structure
分子名称: CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE RNF8, GLYCEROL, ...
著者Mattiroli, F, Vissers, J.H.A, Van Dijk, W.J, Ikpa, P, Citterio, E, Vermeulen, W, Marteijn, J.A, Sixma, T.K.
登録日2012-06-20
公開日2012-09-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rnf168 Ubiquitinates K13-15 on H2A/H2Ax to Drive DNA Damage Signaling
Cell(Cambridge,Mass.), 150, 2012
3RNO
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Crystal Structure of Mouse Apolipoprotein A-I Binding Protein in Complex with NADP.
分子名称: Apolipoprotein A-I-binding protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Shumilin, I.A, Jha, K.N, Cymborowski, M, Herr, J.C, Minor, W.
登録日2011-04-22
公開日2012-05-09
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012
3ROZ
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BU of 3roz by Molmil
Crystal Structure of Mouse Apolipoprotein A-I Binding Protein in Complex with Nicotinamide
分子名称: Apolipoprotein A-I-binding protein, NICOTINAMIDE, SULFATE ION
著者Shumilin, I.A, Jha, K.N, Cymborowski, M, Herr, J.C, Minor, W.
登録日2011-04-26
公開日2012-07-18
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012
4QP2
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Crystal Structure of ERKs in complex with 5-chlorobenzo[d]oxazol-2-amine
分子名称: 5-chloro-1,3-benzoxazol-2-amine, IMIDAZOLE, Mitogen-activated protein kinase 1
著者Yin, J, Wang, W.
登録日2014-06-22
公開日2015-09-23
最終更新日2015-12-16
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
3RQ8
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Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis soaked with P1,P5-Di(adenosine-5') pentaphosphate
分子名称: ADP/ATP-dependent NAD(P)H-hydrate dehydratase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION
著者Shumilin, I.A, Cymborowski, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2011-04-27
公開日2011-07-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012
3RS9
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Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima in complex with P1,P3-Di(adenosine-5') triphosphate
分子名称: BIS(ADENOSINE)-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W.
登録日2011-05-02
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012
3RSQ
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Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, BETA-6-HYDROXY-1,4,5,6-TETRHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, POTASSIUM ION, ...
著者Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W.
登録日2011-05-02
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.054 Å)
主引用文献Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012

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