6N7V
| Structure of bacteriophage T7 gp4 (helicase-primase, E343Q mutant) in complex with ssDNA, dTTP, AC dinucleotide, and CTP (from multiple lead complexes) | 分子名称: | DNA (93-MER), DNA primase/helicase, MAGNESIUM ION, ... | 著者 | Gao, Y, Fox, T, Val, N, Yang, W. | 登録日 | 2018-11-28 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
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6CCR
| Selenomethionyl derivative of a GID4 fragment | 分子名称: | Glucose-induced degradation protein 4 homolog, UNKNOWN ATOM OR ION | 著者 | Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2018-02-07 | 公開日 | 2018-04-04 | 最終更新日 | 2018-04-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway. Nat. Chem. Biol., 14, 2018
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6N7N
| Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I) | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase/helicase, MAGNESIUM ION, ... | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | 登録日 | 2018-11-27 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
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6N9W
| Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2) | 分子名称: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | 登録日 | 2018-12-04 | 公開日 | 2019-03-06 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
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6C7O
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1XM5
| Crystal structure of metal-dependent hydrolase ybeY from E. coli, Pfam UPF0054 | 分子名称: | Hypothetical UPF0054 protein ybeY, NICKEL (II) ION | 著者 | Fedorov, A.A, Fedorov, E.V, Shi, W, Ramagopal, U.A, Thirumuruhan, R, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2004-10-01 | 公開日 | 2004-10-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The ybeY protein from Escherichia coli is a metalloprotein. Acta Crystallogr.,Sect.F, 61, 2005
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5Z1Q
| Crystal structures of the trimeric N-terminal domain of Ciliate Euplotes octocarinatus Centrin | 分子名称: | CALCIUM ION, CHLORIDE ION, Centrin protein | 著者 | Wang, W, Zhao, Y, Yang, B, Wang, H. | 登録日 | 2017-12-27 | 公開日 | 2018-04-25 | 最終更新日 | 2018-06-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the trimeric N-terminal domain of ciliate Euplotes octocarinatus centrin binding with calcium ions Protein Sci., 27, 2018
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1FI7
| Solution structure of the imidazole complex of cytochrome C | 分子名称: | CYTOCHROME C, HEME C, IMIDAZOLE | 著者 | Banci, L, Bertini, I, Liu, G, Lu, J, Reddig, T, Tang, W, Wu, Y, Zhu, D. | 登録日 | 2000-08-03 | 公開日 | 2000-08-23 | 最終更新日 | 2024-10-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Effects of extrinsic imidazole ligation on the molecular and electronic structure of cytochrome c J.Biol.Inorg.Chem., 6, 2001
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1UDE
| Crystal structure of the Inorganic pyrophosphatase from the hyperthermophilic archaeon Pyrococcus horikoshii OT3 | 分子名称: | Inorganic pyrophosphatase | 著者 | Liu, B, Gao, R, Zhou, W, Bartlam, M, Rao, Z. | 登録日 | 2003-04-29 | 公開日 | 2004-01-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Crystal structure of the hyperthermophilic inorganic pyrophosphatase from the archaeon Pyrococcus horikoshii. Biophys.J., 86, 2004
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1XRR
| Crystal structure of active site F1-mutant E245Q soaked with peptide Pro-Pro | 分子名称: | PROLINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-15 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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6C8E
| RNA-imidazolium-bridged intermediate complex, 4h soaking | 分子名称: | 2-amino-1-[(R)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-3-[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3') | 著者 | Zhang, W, Szostak, J.W. | 登録日 | 2018-01-24 | 公開日 | 2018-05-30 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystallographic observation of nonenzymatic RNA primer extension. Elife, 7, 2018
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1FP3
| CRYSTAL STRUCTURE OF N-ACYL-D-GLUCOSAMINE 2-EPIMERASE FROM PORCINE KIDNEY | 分子名称: | N-ACYL-D-GLUCOSAMINE 2-EPIMERASE | 著者 | Itoh, T, Mikami, B, Maru, I, Ohta, Y, Hashimoto, W, Murata, K. | 登録日 | 2000-08-30 | 公開日 | 2000-11-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of N-acyl-D-glucosamine 2-epimerase from porcine kidney at 2.0 A resolution. J.Mol.Biol., 303, 2000
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8G0Y
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8G0X
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1XRN
| Crystal structure of active site F1-mutant E213Q soaked with peptide Phe-Ala | 分子名称: | ALANINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-15 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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5Z9Y
| Crystal structure of Mycobacterium tuberculosis thiazole synthase (ThiG) complexed with DXP | 分子名称: | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, Thiazole synthase | 著者 | Zhang, J, Zhang, B, Zhao, Y, Yang, X, Huang, M, Cui, P, Zhang, W, Li, J, Zhang, Y. | 登録日 | 2018-02-05 | 公開日 | 2018-04-11 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG). Biochem. Biophys. Res. Commun., 497, 2018
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6C2V
| Solution structure of a phosphate-loop protein | 分子名称: | phosphate-loop protein | 著者 | Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G. | 登録日 | 2018-01-09 | 公開日 | 2018-11-21 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Simple yet functional phosphate-loop proteins. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6NEY
| Crystal structure of TcBDF5, a bromodomain containing protein from Trypanosoma cruzi | 分子名称: | Uncharacterized protein | 著者 | Loppnau, P, Dong, A, Tempel, W, Lin, Y.H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Vedadi, M, Harding, R.J, Structural Genomics Consortium (SGC) | 登録日 | 2018-12-18 | 公開日 | 2019-03-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Crystal structure of TcBDF5, a bromodomain containing protein from Trypanosoma cruzi To Be Published
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6NEZ
| Trypanosoma brucei - BDF5, Tb427tmp.01.5000 A, solved with PF-CBP1 | 分子名称: | 5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-benzimidazole, UNKNOWN ATOM OR ION, Uncharacterized protein | 著者 | Lin, Y.H, Dong, A, Tempel, W, McAuley, J, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Vedadi, M, Harding, R.J, Structural Genomics Consortium (SGC) | 登録日 | 2018-12-18 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Trypanosoma brucei - BDF5, Tb427tmp.01.5000 A, solved with PF-CBP1 to be published
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1XUA
| Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens | 分子名称: | (2S,3S)-TRANS-2,3-DIHYDRO-3-HYDROXYANTHRANILIC ACID, Phenazine biosynthesis protein phzF | 著者 | Blankenfeldt, W, Kuzin, A.P, Skarina, T, Korniyenko, Y, Tong, L, Bayer, P, Janning, P, Thomashow, L.S, Mavrodi, D.V. | 登録日 | 2004-10-26 | 公開日 | 2004-11-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens Proc.Natl.Acad.Sci.USA, 101, 2004
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5ZBS
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1U1D
| Structure of e. coli uridine phosphorylase complexed to 5-(phenylthio)acyclouridine (ptau) | 分子名称: | 1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Bu, W, Settembre, E.C, Ealick, S.E. | 登録日 | 2004-07-15 | 公開日 | 2005-07-05 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines. Acta Crystallogr.,Sect.D, 61, 2005
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5ZC9
| Crystal structure of the human eIF4A1-ATP analog-RocA-polypurine RNA complex | 分子名称: | (1R,2R,3S,3aR,8bS)-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-1,8b-bis(oxidanyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide, Eukaryotic initiation factor 4A-I, MAGNESIUM ION, ... | 著者 | Iwasaki, W, Takahashi, M, Sakamoto, A, Iwasaki, S, Ito, T. | 登録日 | 2018-02-16 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA. Mol. Cell, 73, 2019
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1TW0
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5ZHK
| Crystal structure of TrmD from Mycobacterium tuberculosis in complex with active-site inhibitor | 分子名称: | N-[(4-{[cyclohexyl(ethyl)amino]methyl}phenyl)methyl]-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carboxamide, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Zhong, W, Pasunooti, K.K, Balamkundu, S, Wong, Y.W, Nah, Q, Liu, C.F, Lescar, J, Dedon, P.C. | 登録日 | 2018-03-13 | 公開日 | 2019-03-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism. J.Med.Chem., 62, 2019
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