6C7O
Crystal structure of D477G ACO/RPE65 chimera, trigonal crystal form
Summary for 6C7O
Entry DOI | 10.2210/pdb6c7o/pdb |
Descriptor | Apocarotenoid-15,15'-oxygenase, FE (II) ION (3 entities in total) |
Functional Keywords | non-heme iron, chimera, 7-bladed propeller, dominant mutation, oxidoreductase |
Biological source | Synechocystis sp. (strain PCC 6803 / Kazusa) |
Total number of polymer chains | 2 |
Total formula weight | 108914.38 |
Authors | Kiser, P.D.,Shi, W. (deposition date: 2018-01-23, release date: 2018-04-25, Last modification date: 2023-10-04) |
Primary citation | Choi, E.H.,Suh, S.,Sander, C.L.,Hernandez, C.J.O.,Bulman, E.R.,Khadka, N.,Dong, Z.,Shi, W.,Palczewski, K.,Kiser, P.D. Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65. Hum.Mol.Genet., 27:2225-2243, 2018 Cited by PubMed: 29659842DOI: 10.1093/hmg/ddy128 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.15 Å) |
Structure validation
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