3I3G
 
 | | Crystal Structure of Trypanosoma brucei N-acetyltransferase (Tb11.01.2886) at 1.86A | | 分子名称: | N-acetyltransferase | | 著者 | Qiu, W, Wernimont, A.K, Marino, K, Zhang, A.Z, Ma, D, Lin, Y.H, Mackenzie, F, Kozieradzki, I, Cossar, D, Zhao, Y, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, J Ferguson, M.A, Hui, R, Structural Genomics Consortium (SGC) | | 登録日 | 2009-06-30 | | 公開日 | 2009-08-11 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal Structure Trypanosoma brucei N-acetyltransferase (Tb11.01.2886) at 1.86A
To be Published
|
|
2QSY
 | | Human nicotinamide riboside kinase 1 in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nicotinamide riboside kinase 1, ... | | 著者 | Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Brenner, C, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2007-07-31 | | 公開日 | 2007-08-14 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+).
Plos Biol., 5, 2007
|
|
4WQ4
 | | E. coli YgjD(E12A)-YeaZ heterodimer in complex with ATP | | 分子名称: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Zhang, W, Collinet, B. | | 登録日 | 2014-10-21 | | 公開日 | 2015-01-28 | | 最終更新日 | 2015-02-25 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli.
Nucleic Acids Res., 43, 2015
|
|
1XM5
 | | Crystal structure of metal-dependent hydrolase ybeY from E. coli, Pfam UPF0054 | | 分子名称: | Hypothetical UPF0054 protein ybeY, NICKEL (II) ION | | 著者 | Fedorov, A.A, Fedorov, E.V, Shi, W, Ramagopal, U.A, Thirumuruhan, R, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2004-10-01 | | 公開日 | 2004-10-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The ybeY protein from Escherichia coli is a metalloprotein.
Acta Crystallogr.,Sect.F, 61, 2005
|
|
2QU8
 | | Crystal structure of putative nucleolar GTP-binding protein 1 PFF0625w from Plasmodium falciparum | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Putative nucleolar GTP-binding protein 1 | | 著者 | Wernimont, A.K, Lew, J, Lin, Y.H, Kozieradzki, I, Zhao, Y, Ravichandran, M, Shapiro, M, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Qiu, W, Sukumar, D, Hassanali, A, Structural Genomics Consortium (SGC) | | 登録日 | 2007-08-03 | | 公開日 | 2007-08-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Crystal structure of putative nucleolar GTP-binding protein 1 PFF0625w from Plasmodium falciparum.
To be Published
|
|
2QXH
 | | Crystal Structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone | | 分子名称: | Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide | | 著者 | Debela, M, Hess, P, Magdolen, V, Schechter, N.M, Bode, W, Goettig, P. | | 登録日 | 2007-08-11 | | 公開日 | 2008-01-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7.
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
1X9Z
 | | Crystal structure of the MutL C-terminal domain | | 分子名称: | CHLORIDE ION, DNA mismatch repair protein mutL, GLYCEROL, ... | | 著者 | Guarne, A, Ramon-Maiques, S, Wolff, E.M, Ghirlando, R, Hu, X, Miller, J.H, Yang, W. | | 登録日 | 2004-08-24 | | 公開日 | 2004-10-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair
Embo J., 23, 2004
|
|
1XRN
 | | Crystal structure of active site F1-mutant E213Q soaked with peptide Phe-Ala | | 分子名称: | ALANINE, Proline iminopeptidase | | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | | 登録日 | 2004-10-15 | | 公開日 | 2005-07-12 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum
J.Biol.Chem., 280, 2005
|
|
3HRB
 | | p38 kinase Crystal structure in complex with small molecule inhibitor | | 分子名称: | Mitogen-activated protein kinase 14, [3-amino-2-(2-methylphenyl)-1-oxidopyridin-4-yl](2,4-difluorophenyl)methanone | | 著者 | Segarra, V, Lumeras, W, Vidal, B, Leonard, P, Fisher, M, Lamers, M. | | 登録日 | 2009-06-09 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Design, synthesis, and structure-activity relationships of aminopyridine N-oxides, a novel scaffold for the potent and selective inhibition of p38 mitogen activated protein kinase
J.Med.Chem., 52, 2009
|
|
4YDU
 | | Crystal structure of E. coli YgjD-YeaZ heterodimer in complex with ADP | | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, ... | | 著者 | Zhang, W, Collinet, B, Perrochia, L, Durand, D, Van Tilbeurgh, H. | | 登録日 | 2015-02-23 | | 公開日 | 2015-03-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli.
Nucleic Acids Res., 43, 2015
|
|
1XUA
 | | Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens | | 分子名称: | (2S,3S)-TRANS-2,3-DIHYDRO-3-HYDROXYANTHRANILIC ACID, Phenazine biosynthesis protein phzF | | 著者 | Blankenfeldt, W, Kuzin, A.P, Skarina, T, Korniyenko, Y, Tong, L, Bayer, P, Janning, P, Thomashow, L.S, Mavrodi, D.V. | | 登録日 | 2004-10-26 | | 公開日 | 2004-11-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens
Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
3MW1
 | | p38 kinase Crystal structure in complex with small molecule inhibitor | | 分子名称: | 8-(2,6-dichlorophenyl)-4-(2,4-difluorophenyl)-2-piperidin-4-yl-1,7-naphthyridine 7-oxide, Mitogen-activated protein kinase 14 | | 著者 | Segarra, V, Caturla, F, Lumeras, W, Roca, R, Fisher, M, Lamers, M. | | 登録日 | 2010-05-05 | | 公開日 | 2011-04-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | 1,7-Naphthyridine 1-Oxides as Novel Potent and Selective Inhibitors of p38 Mitogen Activated Protein Kinase
J.Med.Chem., 54, 2011
|
|
4YJY
 | |
7TNY
 | | Cryo-EM structure of RIG-I in complex with p2dsRNA | | 分子名称: | Antiviral innate immune response receptor RIG-I, ZINC ION, p2dsRNA | | 著者 | Wang, W, Pyle, A.M. | | 登録日 | 2022-01-22 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
|
|
1C6S
 | | THE SOLUTION STRUCTURE OF CYTOCHROME C6 FROM THE THERMOPHILIC CYANOBACTERIUM SYNECHOCOCCUS ELONGATUS, NMR, 20 STRUCTURES | | 分子名称: | CYTOCHROME C6, HEME C | | 著者 | Roesch, P, Beissinger, M, Sticht, H, Sutter, M, Ejchart, A, Haehnel, W. | | 登録日 | 1997-03-31 | | 公開日 | 1998-04-08 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of cytochrome c6 from the thermophilic cyanobacterium Synechococcus elongatus.
EMBO J., 17, 1998
|
|
6KLR
 | |
3MYG
 | | Aurora A Kinase complexed with SCH 1473759 | | 分子名称: | 2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol, Serine/threonine-protein kinase 6, TETRAETHYLENE GLYCOL | | 著者 | Hruza, A, Prosis, W, Ramanathan, L. | | 登録日 | 2010-05-10 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core.
ACS Med Chem Lett, 1, 2010
|
|
1XH5
 | | Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants | | 分子名称: | (R,R)-2,3-BUTANEDIOL, N-{4-[(4-{3-[(2R)-3,3-DIMETHYLPIPERIDIN-2-YL]-2-FLUORO-6-HYDROXYBENZOYL}BENZOYL)AMINO]AZEPAN-3-YL}ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, ... | | 著者 | Breitenlechner, C.B, Friebe, W.-G, Brunet, E, Werner, G, Graul, K, Thomas, U, Kuenkele, K.-P, Schaefer, W, Gassel, M, Bossemeyer, D, Huber, R, Engh, R.A, Masjost, B. | | 登録日 | 2004-09-17 | | 公開日 | 2005-09-17 | | 最終更新日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants
J.Med.Chem., 48, 2005
|
|
1XI8
 | | Molybdenum cofactor biosynthesis protein from Pyrococcus furiosus Pfu-1657500-001 | | 分子名称: | Molybdenum cofactor biosynthesis protein | | 著者 | Zhou, W, Zhao, M, Chang, J.C, Liu, Z.-J, Chen, L, Horanyi, P, Xu, H, Yang, H, Habel, J.E, Lee, D, Chang, S.-H, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2004-09-21 | | 公開日 | 2004-11-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.504 Å) | | 主引用文献 | Molybdenum cofactor biosynthesis protein from Pyrococcus furiosus Pfu-1657500-001
To be published
|
|
7TQN
 | |
2WFU
 | | Crystal structure of DILP5 variant DB | | 分子名称: | PROBABLE INSULIN-LIKE PEPTIDE 5 A CHAIN, PROBABLE INSULIN-LIKE PEPTIDE 5 B CHAIN | | 著者 | Kulahin, N, Schluckebier, G, Sajid, W, De Meyts, P. | | 登録日 | 2009-04-15 | | 公開日 | 2010-05-26 | | 最終更新日 | 2012-04-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and Biological Properties of the Drosophila Insulin-Like Peptide 5 Show Evolutionary Conservation.
J.Biol.Chem., 286, 2011
|
|
3I4P
 | | Crystal structure of AsnC family transcriptional regulator from Agrobacterium tumefaciens | | 分子名称: | ACETATE ION, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Cymborowski, M, Chruszcz, M, Luo, H, Xu, X, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2009-07-02 | | 公開日 | 2009-07-28 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of AsnC family transcriptional regulator from Agrobacterium tumefaciens
To be Published
|
|
1XH4
 | | Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants | | 分子名称: | N-[4-({4-[5-(DIMETHYLAMINO)-2-HYDROXYBENZOYL]BENZOYL}AMINO)AZEPAN-3-YL]ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | | 著者 | Breitenlechner, C.B, Friebe, W.-G, Brunet, E, Werner, G, Graul, K, Thomas, U, Kuenkele, K.-P, Schaefer, W, Gassel, M, Bossemeyer, D, Huber, R, Engh, R.A, Masjost, B. | | 登録日 | 2004-09-17 | | 公開日 | 2005-09-17 | | 最終更新日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants
J.Med.Chem., 48, 2005
|
|
3HS9
 | | Intersectin 1-peptide-AP2 beta ear complex | | 分子名称: | AP-2 complex subunit beta-1, peptide from Intersectin-1, residues 841-851 | | 著者 | Vahedi-Faridi, A, Pechstein, A, Schaefer, J.G, Saenger, W, Haucke, V. | | 登録日 | 2009-06-10 | | 公開日 | 2010-02-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
1XRR
 | | Crystal structure of active site F1-mutant E245Q soaked with peptide Pro-Pro | | 分子名称: | PROLINE, Proline iminopeptidase | | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | | 登録日 | 2004-10-15 | | 公開日 | 2005-07-12 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum
J.Biol.Chem., 280, 2005
|
|
