5D45
| Crystal Structure of FABP4 in complex with 3-(5-cyclopropyl-2,3-diphenyl-1H-indol-1-yl)propanoic acid | 分子名称: | 3-(5-cyclopropyl-2,3-diphenyl-1H-indol-1-yl)propanoic acid, Fatty acid-binding protein, adipocyte | 著者 | Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T. | 登録日 | 2015-08-07 | 公開日 | 2016-06-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis Acs Med.Chem.Lett., 7, 2016
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8TEP
| Human cytomegalovirus portal vertex, virion configuration 1 (VC1) | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Inner tegument protein, ... | 著者 | Jih, J, Liu, Y.T, Liu, W, Zhou, H. | 登録日 | 2023-07-06 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The incredible bulk: Human cytomegalovirus tegument architectures uncovered by AI-empowered cryo-EM. Sci Adv, 10, 2024
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8OSV
| Structural and functional studies of geldanamycin amide synthase ShGdmF | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Ewert, W, Zeilinger, C, Kirschning, A, Preller, M. | 登録日 | 2023-04-20 | 公開日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Structural and functional studies of geldanamycin amide synthase ShGdmF To Be Published
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5JE7
| Human carbonic anhydrase II (F131Y) complexed with benzo[d]thiazole-2-sulfonamide | 分子名称: | 1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION | 著者 | Fox, J.M, Kang, K, Sastry, M, Sherman, W, Sankaran, B, Zwart, P.H, Whitesides, G.M. | 登録日 | 2016-04-17 | 公開日 | 2017-01-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase. Angew. Chem. Int. Ed. Engl., 56, 2017
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8OUG
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5JGL
| Crystal structure of GtmA in complex with S-Adenosylmethionine | 分子名称: | S-ADENOSYLMETHIONINE, SODIUM ION, UbiE/COQ5 family methyltransferase, ... | 著者 | Dolan, S.K, Bock, T, Hering, V, Jones, G.W, Blankenfeldt, W, Doyle, S. | 登録日 | 2016-04-20 | 公開日 | 2017-03-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Structural, mechanistic and functional insight into gliotoxinbis-thiomethylation inAspergillus fumigatus. Open Biol, 7, 2017
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8TGI
| VMAT1 dimer with dopamine and reserpine | 分子名称: | Chromaffin granule amine transporter, L-DOPAMINE, reserpine | 著者 | Ye, J, Liu, B, Li, W. | 登録日 | 2023-07-12 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8FZR
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8TGJ
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8OSZ
| Structural and functional studies of geldanamycin amide synthase ShGdmF | 分子名称: | 3-aminophenol, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Ewert, W, Zeilinger, C, Kirschning, A, Preller, M. | 登録日 | 2023-04-20 | 公開日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Structural and functional studies of geldanamycin amide synthase ShGdmF To Be Published
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8TGK
| VMAT1 dimer with histamine and reserpine | 分子名称: | Chromaffin granule amine transporter, HISTAMINE, reserpine | 著者 | Ye, J, Liu, B, Li, W. | 登録日 | 2023-07-12 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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6NUC
| Structure of Calcineurin in complex with NHE1 peptide | 分子名称: | CALCIUM ION, Calcineurin subunit B type 1, DI(HYDROXYETHYL)ETHER, ... | 著者 | Wang, X, Page, R, Peti, W. | 登録日 | 2019-01-31 | 公開日 | 2019-07-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular basis for the binding and selective dephosphorylation of Na+/H+exchanger 1 by calcineurin. Nat Commun, 10, 2019
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8U4C
| Cryo-EM structure of long form insulin receptor (IR-B) with four IGF2 bound, symmetric conformation. | 分子名称: | Insulin receptor, Insulin-like growth factor II | 著者 | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | 登録日 | 2023-09-10 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8OT2
| Structural and functional studies of geldanamycin amide synthase ShGdmF | 分子名称: | 1,2-ETHANEDIOL, 3-azanyl-5-methyl-phenol, ACETATE ION, ... | 著者 | Ewert, W, Zeilinger, C, Kirschning, A, Preller, M. | 登録日 | 2023-04-20 | 公開日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structural and functional studies of geldanamycin amide synthase ShGdmF To Be Published
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5DFY
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8TEU
| Human cytomegalovirus portal vertex, non-infectious enveloped particle (NIEP) configuration 2 - inverted (NC2-inv) | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large structural phosphoprotein, ... | 著者 | Jih, J, Liu, Y.T, Liu, W, Zhou, H. | 登録日 | 2023-07-07 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.01 Å) | 主引用文献 | The incredible bulk: Human cytomegalovirus tegument architectures uncovered by AI-empowered cryo-EM. Sci Adv, 10, 2024
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1H2D
| Ebola virus matrix protein VP40 N-terminal domain in complex with RNA (Low-resolution VP40[31-212] variant). | 分子名称: | 5'-R(*UP*GP*AP)-3', CHLORIDE ION, MATRIX PROTEIN VP40 | 著者 | Gomis-Ruth, F.X, Dessen, A, Bracher, A, Klenk, H.D, Weissenhorn, W. | 登録日 | 2002-08-06 | 公開日 | 2003-04-10 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Matrix Protein Vp40 from Ebola Virus Octamerizes Into Pore-Like Structures with Specific RNA Binding Properties Structure, 11, 2003
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8U4E
| Cryo-EM structure of long form insulin receptor (IR-B) with three IGF2 bound, asymmetric conformation. | 分子名称: | Insulin receptor, Insulin-like growth factor II | 著者 | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | 登録日 | 2023-09-10 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8TNT
| Crystal structure of Epstein-Barr virus gH/gL/gp42 in complex with antibodies F-2-1 and 769C2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 769C2 heavy chain, 769C2 light chain, ... | 著者 | Bu, W, Kumar, A, Board, N, Kim, J, Dowdell, K, Zhang, S, Lei, Y, Hostal, A, Krogmann, T, Wang, Y, Pittaluga, S, Marcotrigiano, J, Cohen, J.I. | 登録日 | 2023-08-02 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells. Immunity, 57, 2024
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5J19
| phospho-Pon binding-induced Plk1 dimerization | 分子名称: | GLYCEROL, Phosphorylated peptide from Partner of Numb, Serine/threonine-protein kinase PLK1 | 著者 | Zhu, K, Shan, Z, Zhang, L, Wen, W. | 登録日 | 2016-03-29 | 公開日 | 2016-06-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Phospho-Pon Binding-Mediated Fine-Tuning of Plk1 Activity Structure, 24, 2016
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8TEW
| Human cytomegalovirus penton vertex, CVSC-bound configuration | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large structural phosphoprotein, ... | 著者 | Jih, J, Liu, Y.T, Liu, W, Zhou, H. | 登録日 | 2023-07-07 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | The incredible bulk: Human cytomegalovirus tegument architectures uncovered by AI-empowered cryo-EM. Sci Adv, 10, 2024
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8U4B
| Cryo-EM structure of long form insulin receptor (IR-B) in the apo state | 分子名称: | Insulin receptor | 著者 | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | 登録日 | 2023-09-10 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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5A9U
| Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile). | 分子名称: | (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile, ALK TYROSINE KINASE RECEPTOR | 著者 | McTigue, M, Deng, Y.-L, Liu, W, Brooun, A, Stewart, A. | 登録日 | 2015-07-22 | 公開日 | 2016-06-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Resensitization to Crizotinib by the Lorlatinib Alk Resistance Mutation L1198F. N.Engl.J.Med., 374, 2016
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8TOO
| Crystal structure of Epstein-Barr virus gp42 in complex with antibody 4C12 | 分子名称: | 4C12 heavy chain, 4C12 light chain, Glycoprotein 42 | 著者 | Bu, W, Kumar, A, Board, N, Kim, J, Dowdell, K, Zhang, S, Lei, Y, Hostal, A, Krogmann, T, Wang, Y, Pittaluga, S, Marcotrigiano, J, Cohen, J.I. | 登録日 | 2023-08-03 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells. Immunity, 57, 2024
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5J3E
| Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA | 分子名称: | 5-methylcytosine containing DNA, Thymocyte nuclear protein 1, UNKNOWN ATOM OR ION | 著者 | Halabelian, L, Tempel, W, Li, Y, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | 登録日 | 2016-03-30 | 公開日 | 2016-04-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA To be published
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