3T2F
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![BU of 3t2f by Molmil](/molmil-images/mine/3t2f) | Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, soaked with EDTA and DHAP | Descriptor: | Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | Authors: | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | Deposit date: | 2011-07-22 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase. Nature, 478, 2011
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3FM8
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![BU of 3fm8 by Molmil](/molmil-images/mine/3fm8) | Crystal structure of full length centaurin alpha-1 bound with the FHA domain of KIF13B (CAPRI target) | Descriptor: | Centaurin-alpha-1, Kinesin-like protein KIF13B, SULFATE ION, ... | Authors: | Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-12-19 | Release date: | 2009-08-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1. Proc.Natl.Acad.Sci.USA, 107, 2010
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2JED
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![BU of 2jed by Molmil](/molmil-images/mine/2jed) | The crystal structure of the kinase domain of the protein kinase C theta in complex with NVP-XAA228 at 2.32A resolution. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-(8-DIMETHYLAMINOMETHYL-6,7,8,9-TETRAHYDRO-PYRIDO[1,2-A]INDOL-10-YL)-4-(1-METHYL-1H-INDOL-3-YL)-PYRROLE-2,5-DIONE, PROTEIN KINASE C THETA | Authors: | Stark, W, Bitsch, F, Berner, A, Buelens, F, Graff, P, Depersin, H, Geiser, M, Knecht, R, Rahuel, J, Rummel, G, Schlaeppi, J.M, Schmitz, R, Strauss, A, Wagner, J. | Deposit date: | 2007-01-16 | Release date: | 2008-02-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | The Crystal Structure of the Kinase Domain of the Protein Kinase C Theta in Complex with Nvp-Xaa228 To be Published
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2B2U
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![BU of 2b2u by Molmil](/molmil-images/mine/2b2u) | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and dimethylarginine 2 | Descriptor: | Chromodomain-helicase-DNA-binding protein 1, Histone H3 | Authors: | Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S. | Deposit date: | 2005-09-19 | Release date: | 2005-12-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Double chromodomains cooperate to recognize the methylated histone H3 tail. Nature, 438, 2005
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2JUU
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![BU of 2juu by Molmil](/molmil-images/mine/2juu) | allo-ThrA3 DKP-insulin | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 2007-09-03 | Release date: | 2007-10-16 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE. J.Biol.Chem., 282, 2007
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2K3Q
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![BU of 2k3q by Molmil](/molmil-images/mine/2k3q) | |
2B99
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![BU of 2b99 by Molmil](/molmil-images/mine/2b99) | Crystal Structure of an archaeal pentameric riboflavin synthase Complex with a Substrate analog inhibitor | Descriptor: | 6,7-DIOXO-5H-8-RIBITYLAMINOLUMAZINE, Riboflavin synthase | Authors: | Ramsperger, A, Augustin, M, Schott, A.K, Gerhardt, S, Krojer, T, Eisenreich, W, Illarionov, B, Cushman, M, Bacher, A, Huber, R, Fischer, M. | Deposit date: | 2005-10-11 | Release date: | 2005-11-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Crystal Structure of an Archaeal Pentameric Riboflavin Synthase in Complex with a Substrate Analog Inhibitor: stereochemical implications J.Biol.Chem., 281, 2006
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2JUM
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![BU of 2jum by Molmil](/molmil-images/mine/2jum) | ThrA3-DKP-insulin | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 2007-08-31 | Release date: | 2007-10-16 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE. J.Biol.Chem., 282, 2007
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2B2V
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![BU of 2b2v by Molmil](/molmil-images/mine/2b2v) | Crystal structure analysis of human CHD1 chromodomains 1 and 2 bound to histone H3 resi 1-15 MeK4 | Descriptor: | Chromodomain-helicase-DNA-binding protein 1, Histone H3 | Authors: | Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S. | Deposit date: | 2005-09-19 | Release date: | 2005-12-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Double chromodomains cooperate to recognize the methylated histone H3 tail. Nature, 438, 2005
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2B5D
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![BU of 2b5d by Molmil](/molmil-images/mine/2b5d) | Crystal structure of the novel alpha-amylase AmyC from Thermotoga maritima | Descriptor: | alpha-Amylase | Authors: | Dickmanns, A, Ballschmiter, M, Liebl, W, Ficner, R. | Deposit date: | 2005-09-28 | Release date: | 2006-03-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the novel alpha-amylase AmyC from Thermotoga maritima. Acta Crystallogr.,Sect.D, 62, 2006
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2B6H
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![BU of 2b6h by Molmil](/molmil-images/mine/2b6h) | Structure of human ADP-ribosylation factor 5 | Descriptor: | ADP-ribosylation factor 5, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Tempel, W, Atanassova, A, Sundarajan, E, Dimov, S, Shehab, I, Lew, J, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2005-10-01 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.764 Å) | Cite: | Structure of human ADP-ribosylation factor 5 To be Published
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2B90
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![BU of 2b90 by Molmil](/molmil-images/mine/2b90) | Crystal structure of the interleukin-4 variant T13DR85A | Descriptor: | Interleukin-4, SULFATE ION | Authors: | Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D. | Deposit date: | 2005-10-10 | Release date: | 2006-05-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor Bmc Biol., 4, 2006
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2B98
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![BU of 2b98 by Molmil](/molmil-images/mine/2b98) | Crystal Structure of an archaeal pentameric riboflavin synthase | Descriptor: | Riboflavin synthase | Authors: | Ramsperger, A, Augustin, M, Schott, A.K, Gerhardt, S, Krojer, T, Eisenreich, W, Illarionov, B, Cushman, M, Bacher, A, Huber, R, Fischer, M. | Deposit date: | 2005-10-11 | Release date: | 2005-11-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of an Archaeal Pentameric Riboflavin Synthase in Complex with a Substrate Analog Inhibitor: stereochemical implications J.Biol.Chem., 281, 2006
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2JSN
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2B8U
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![BU of 2b8u by Molmil](/molmil-images/mine/2b8u) | Crystal structure of wildtype human Interleukin-4 | Descriptor: | Interleukin-4, SULFATE ION | Authors: | Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D. | Deposit date: | 2005-10-10 | Release date: | 2006-05-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor Bmc Biol., 4, 2006
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2B8Y
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![BU of 2b8y by Molmil](/molmil-images/mine/2b8y) | Crystal structure of the interleukin-4 variant T13DF82D | Descriptor: | Interleukin-4, SULFATE ION | Authors: | Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D. | Deposit date: | 2005-10-10 | Release date: | 2006-05-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor Bmc Biol., 4, 2006
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2JKH
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![BU of 2jkh by Molmil](/molmil-images/mine/2jkh) | Factor Xa - cation inhibitor complex | Descriptor: | 3-[(3~{a}~{S},4~{R},8~{a}~{S},8~{b}~{R})-4-[5-(5-chloranylthiophen-2-yl)-1,2-oxazol-3-yl]-1,3-bis(oxidanylidene)-4,6,7,8,8~{a},8~{b}-hexahydro-3~{a}~{H}-pyrrolo[3,4-a]pyrrolizin-2-yl]propyl-trimethyl-azanium, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ... | Authors: | Salonen, L.M, Bucher, C, Banner, D.W, Benz, J, Haap, W, Mary, J.L, Schweizer, W.B, Seiler, P, Kuster, O, Diederich, F. | Deposit date: | 2008-08-28 | Release date: | 2009-01-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Cation-Pi Interactions at the Active Site of Factor Xa: Dramatic Enhancement Upon Stepwise N-Alkylation of Ammonium Ions. Angew.Chem.Int.Ed.Engl., 48, 2009
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2JMK
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![BU of 2jmk by Molmil](/molmil-images/mine/2jmk) | Solution structure of ta0956 | Descriptor: | Hypothetical protein Ta0956 | Authors: | Koo, B, Jung, J, Jung, H, Nam, H, Kim, Y, Yee, A, Arrowsmith, C.H, Lee, W. | Deposit date: | 2006-11-20 | Release date: | 2007-10-02 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the hypothetical novel-fold protein TA0956 from Thermoplasma acidophilum Proteins, 69, 2007
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2DG2
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![BU of 2dg2 by Molmil](/molmil-images/mine/2dg2) | Crystal Structure of Mouse Apolipoprotein A-I Binding Protein | Descriptor: | Apolipoprotein A-I binding protein, CHLORIDE ION, SULFATE ION | Authors: | Shumilin, I.A, Jha, K.N, Zheng, H, Chruszcz, M, Cymborowski, M, Herr, J.C, Minor, W. | Deposit date: | 2006-03-08 | Release date: | 2007-03-27 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Biochemical and structural characterization of apolipoprotein A-I binding protein, a novel phosphoprotein with a potential role in sperm capacitation. Endocrinology, 149, 2008
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2DHO
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![BU of 2dho by Molmil](/molmil-images/mine/2dho) | Crystal structure of human IPP isomerase I in space group P212121 | Descriptor: | CHLORIDE ION, Isopentenyl-diphosphate delta-isomerase 1, MANGANESE (II) ION, ... | Authors: | Zhang, C, Wei, Z, Gong, W. | Deposit date: | 2006-03-24 | Release date: | 2007-06-05 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structures of human IPP isomerase: new insights into the catalytic mechanism J.Mol.Biol., 366, 2007
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2JSO
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![BU of 2jso by Molmil](/molmil-images/mine/2jso) | Antimicrobial resistance protein | Descriptor: | Polymyxin resistance protein pmrD | Authors: | Jin, C, Fu, W. | Deposit date: | 2007-07-10 | Release date: | 2007-09-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | First structure of the polymyxin resistance proteins. Biochem.Biophys.Res.Commun., 361, 2007
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3T2E
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![BU of 3t2e by Molmil](/molmil-images/mine/3t2e) | Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, F6P-bound form | Descriptor: | FRUCTOSE -6-PHOSPHATE, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | Authors: | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | Deposit date: | 2011-07-22 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase. Nature, 478, 2011
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2K3P
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3T9I
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![BU of 3t9i by Molmil](/molmil-images/mine/3t9i) | Pim1 complexed with a novel 3,6-disubstituted indole at 2.6 Ang Resolution | Descriptor: | 2-methoxy-4-(3-phenyl-2H-pyrazolo[3,4-b]pyridin-6-yl)phenol, Proto-oncogene serine/threonine-protein kinase pim-1 | Authors: | Bellamacina, C, Shu, W, Le, V, Nishiguchi, G, Bussiere, D. | Deposit date: | 2011-08-02 | Release date: | 2011-10-12 | Last modified: | 2011-11-02 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases. Bioorg.Med.Chem.Lett., 21, 2011
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2DIT
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![BU of 2dit by Molmil](/molmil-images/mine/2dit) | Solution structure of the RRM_1 domain of HIV TAT specific factor 1 variant | Descriptor: | HIV TAT specific factor 1 variant | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-03-30 | Release date: | 2006-09-30 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the RRM_1 domain of HIV TAT specific factor 1 variant To be Published
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