1SAN
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8GEX
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8G9O
| Complete DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-02-21 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8G99
| Partial auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... | Authors: | Mullins, E.A, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-02-21 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8G9F
| Complete auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Mullins, E.A, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-02-21 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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6N2M
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6N2P
| Helical assembly of the CARD9 CARD | Descriptor: | Caspase recruitment domain-containing protein 9 | Authors: | Holliday, M.J, Rohou, A, Arthur, C.P, Dueber, E.C, Fairbrother, W.J. | Deposit date: | 2018-11-13 | Release date: | 2019-07-03 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation. Nat Commun, 10, 2019
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3LRP
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3L9Q
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3NJ6
| 0.95 A resolution X-ray structure of (GGCAGCAGCC)2 | Descriptor: | 5'-R(*GP*GP*CP*AP*GP*CP*AP*GP*CP*C)-3', SULFATE ION | Authors: | Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, W. | Deposit date: | 2010-06-17 | Release date: | 2010-08-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases. Nucleic Acids Res., 38, 2010
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3NJ7
| 1.9 A resolution X-ray structure of (GGCAGCAGCC)2 | Descriptor: | 5'-R(*GP*GP*CP*AP*GP*CP*AP*GP*CP*C)-3', SULFATE ION | Authors: | Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, W. | Deposit date: | 2010-06-17 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.904 Å) | Cite: | Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases. Nucleic Acids Res., 38, 2010
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3OSF
| The structure of protozoan parasite Trichomonas vaginalis Myb2 in complex with MRE-2f-13 DNA | Descriptor: | 5'-D(*CP*AP*AP*GP*AP*CP*GP*AP*TP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*AP*TP*CP*GP*TP*CP*TP*TP*G)-3', ISOPROPYL ALCOHOL, ... | Authors: | Jiang, I, Tsai, C.K, Chen, S.C, Wang, S.H, Amiraslanov, I, Chang, C.F, Wu, W.J, Tai, J.H, Liaw, Y.C, Huang, T.H. | Deposit date: | 2010-09-09 | Release date: | 2011-08-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.032 Å) | Cite: | Molecular basis of the recognition of the ap65-1 gene transcription promoter elements by a Myb protein from the protozoan parasite Trichomonas vaginalis. Nucleic Acids Res., 39, 2011
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3OSG
| The structure of protozoan parasite Trichomonas vaginalis Myb2 in complex with MRE-1-12 DNA | Descriptor: | 5'-D(*AP*AP*AP*TP*AP*TP*CP*GP*TP*TP*AP*T)-3', 5'-D(*AP*TP*AP*AP*CP*GP*AP*TP*AP*TP*TP*T)-3', MYB21 | Authors: | Jiang, I, Tsai, C.K, Chen, S.C, Wang, S.H, Amiraslanov, I, Chang, C.F, Wu, W.J, Tai, J.H, Liaw, Y.C, Huang, T.H. | Deposit date: | 2010-09-09 | Release date: | 2011-08-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Molecular basis of the recognition of the ap65-1 gene transcription promoter elements by a Myb protein from the protozoan parasite Trichomonas vaginalis. Nucleic Acids Res., 39, 2011
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3P16
| Crystal structure of DNA polymerase III sliding clamp | Descriptor: | DNA polymerase III subunit beta | Authors: | Gui, W.J, Lin, S.Q, Chen, Y.Y, Zhang, X.E, Bi, L.J, Jiang, T. | Deposit date: | 2010-09-30 | Release date: | 2011-08-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Crystal structure of DNA polymerase III beta sliding clamp from Mycobacterium tuberculosis. Biochem.Biophys.Res.Commun., 405, 2011
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3LRV
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1Z1D
| Structural Model for the interaction between RPA32 C-terminal domain and SV40 T antigen origin binding domain. | Descriptor: | Large T antigen, Replication protein A 32 kDa subunit | Authors: | Arunkumar, A.I, Klimovich, V, Jiang, X, Ott, R.D, Mizoue, L, Fanning, E, Chazin, W.J. | Deposit date: | 2005-03-03 | Release date: | 2005-05-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Insights into hRPA32 C-terminal domain--mediated assembly of the simian virus 40 replisome. Nat.Struct.Mol.Biol., 12, 2005
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2AAK
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6AK5
| Binary Complex of Human DNA Polymerase Mu with MnGTP | Descriptor: | DNA-directed DNA/RNA polymerase mu, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Chang, Y.K, Wu, W.J, Tsai, M.D. | Deposit date: | 2018-08-30 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
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6AK9
| Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Cytosine and Incoming Ca-8oxodGTP | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Chang, Y.K, Wu, W.J, Tsai, M.D. | Deposit date: | 2018-08-30 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
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6AEC
| Binary complex of human DNA Polymerase Mu with MnATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ... | Authors: | Chang, Y.K, Wu, W.J, Tsai, M.D. | Deposit date: | 2018-08-04 | Release date: | 2019-05-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
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6AK8
| Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Adenine and Incoming Ca-8oxodGTP | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Chang, Y.K, Wu, W.J, Tsai, M.D. | Deposit date: | 2018-08-30 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
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6AKH
| Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Adenine and Incoming Mn-dUMPNPP | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Chang, Y.K, Wu, W.J, Tsai, M.D. | Deposit date: | 2018-08-31 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
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6AEH
| Binary complex of human DNA Polymerase Mu with MnUTP | Descriptor: | DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, SULFATE ION, ... | Authors: | Chang, Y.K, Wu, W.J, Tsai, M.D. | Deposit date: | 2018-08-04 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
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6AI5
| Disulfide-free, Zn-directed tetramer of the engineered cyt cb562 variant, C96T/A104AB3 | Descriptor: | CHLORIDE ION, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Song, W.J, Tezcan, F.A. | Deposit date: | 2018-08-21 | Release date: | 2019-09-11 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Disulfide-free, Zn-directed tetramer of the engineered cyt cb562 variant, C96T/A104AB3 To Be Published
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6AK6
| Binary Complex of Human DNA Polymerase Mu with MnCTP | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ... | Authors: | Chang, Y.K, Wu, W.J, Tsai, M.D. | Deposit date: | 2018-08-30 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
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