6N2P
Helical assembly of the CARD9 CARD
Summary for 6N2P
Entry DOI | 10.2210/pdb6n2p/pdb |
Related | 6N2M |
EMDB information | 9332 |
Descriptor | Caspase recruitment domain-containing protein 9 (1 entity in total) |
Functional Keywords | card, filament, helical assembly, death domain, innate immunity, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 10 |
Total formula weight | 173518.73 |
Authors | Holliday, M.J.,Rohou, A.,Arthur, C.P.,Dueber, E.C.,Fairbrother, W.J. (deposition date: 2018-11-13, release date: 2019-07-03, Last modification date: 2024-03-20) |
Primary citation | Holliday, M.J.,Witt, A.,Rodriguez Gama, A.,Walters, B.T.,Arthur, C.P.,Halfmann, R.,Rohou, A.,Dueber, E.C.,Fairbrother, W.J. Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation. Nat Commun, 10:3070-3070, 2019 Cited by PubMed: 31296852DOI: 10.1038/s41467-019-10953-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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