6N2P

Helical assembly of the CARD9 CARD

Summary for 6N2P

• Entry DOI: 10.2210/pdb6n2p/pdb
• Related: 6N2M
• EMDB information: 9332
• Descriptor: Caspase recruitment domain-containing protein 9 (1 entity in total)
• Functional Keywords: card, filament, helical assembly, death domain, innate immunity, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 10
• Total formula weight: 173518.73

Authors

Holliday, M.J.,Rohou, A.,Arthur, C.P.,Dueber, E.C.,Fairbrother, W.J. (deposition date: 2018-11-13, release date: 2019-07-03, Last modification date: 2024-03-20)

• Primary citation: Holliday, M.J.,Witt, A.,Rodriguez Gama, A.,Walters, B.T.,Arthur, C.P.,Halfmann, R.,Rohou, A.,Dueber, E.C.,Fairbrother, W.J.; Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation.; Nat Commun, 10:3070-3070, 2019; PubMed: 31296852; DOI: 10.1038/s41467-019-10953-z

Experimental method

ELECTRON MICROSCOPY (4 Å)