6J1V
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![BU of 6j1v by Molmil](/molmil-images/mine/6j1v) | The structure of HLA-A*3003/RT313 | 分子名称: | Beta-2-microglobulin, HLA-A*3003, RT313 | 著者 | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, G.F, Lou, Y.L, Liu, W.J. | 登録日 | 2018-12-29 | 公開日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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6J2J
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![BU of 6j2j by Molmil](/molmil-images/mine/6j2j) | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with MERS-CoV-derived peptide MERS-CoV-S3 | 分子名称: | Beta-2-microglobulin, MERS-CoV-S3, Ptal-N*01:01 | 著者 | Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J. | 登録日 | 2019-01-01 | 公開日 | 2019-09-18 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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3VJD
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![BU of 3vjd by Molmil](/molmil-images/mine/3vjd) | Crystal structure of the Y248A mutant of C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus | 分子名称: | Dehydrosqualene synthase, L(+)-TARTARIC ACID | 著者 | Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J. | 登録日 | 2011-10-14 | 公開日 | 2012-04-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase J.Biol.Chem., 287, 2012
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3VJC
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![BU of 3vjc by Molmil](/molmil-images/mine/3vjc) | Crystal structure of the human squalene synthase in complex with zaragozic acid A | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, Squalene synthase, ... | 著者 | Liu, C.I, Jeng, W.Y, Chang, W.J, Ko, T.P, Wang, A.H.J. | 登録日 | 2011-10-14 | 公開日 | 2012-04-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase J.Biol.Chem., 287, 2012
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3VYN
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![BU of 3vyn by Molmil](/molmil-images/mine/3vyn) | Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase LdtMt2 N55 truncation mutant (resideus 55-408) | 分子名称: | Probable conserved lipoprotein LPPS | 著者 | Li, W.J, Li, D.F, Bi, L.J, Wang, D.C. | 登録日 | 2012-09-30 | 公開日 | 2013-06-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis Cell Res., 23, 2013
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3VJ9
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![BU of 3vj9 by Molmil](/molmil-images/mine/3vj9) | Crystal structure of the human squalene synthase | 分子名称: | CALCIUM ION, NICKEL (II) ION, Squalene synthase | 著者 | Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J. | 登録日 | 2011-10-14 | 公開日 | 2012-04-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase J.Biol.Chem., 287, 2012
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3VYP
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![BU of 3vyp by Molmil](/molmil-images/mine/3vyp) | Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase LdtMt2-N140 adduct with meropenem | 分子名称: | (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, GLYCEROL, Probable conserved lipoprotein LPPS | 著者 | Li, W.J, Li, D.F, Bi, L.J, Wang, D.C. | 登録日 | 2012-09-30 | 公開日 | 2013-06-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis Cell Res., 23, 2013
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3VJ8
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![BU of 3vj8 by Molmil](/molmil-images/mine/3vj8) | |
6IPJ
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![BU of 6ipj by Molmil](/molmil-images/mine/6ipj) | Binary Complex of Human DNA Polymerase Mu with MndTTP | 分子名称: | DNA-directed DNA/RNA polymerase mu,DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, SULFATE ION, ... | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | 登録日 | 2018-11-03 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
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6K7T
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![BU of 6k7t by Molmil](/molmil-images/mine/6k7t) | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV1--human beta-2 microglobulin | 分子名称: | Beta-2-microglobulin, HeV1, MHC class I antigen | 著者 | Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J. | 登録日 | 2019-06-08 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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6IPM
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![BU of 6ipm by Molmil](/molmil-images/mine/6ipm) | Binary Complex of Human DNA Polymerase Mu with MgdCTP | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, ... | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | 登録日 | 2018-11-03 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
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6HNK
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![BU of 6hnk by Molmil](/molmil-images/mine/6hnk) | The ligand-free, open structure of CD0873, a substrate binding protein with adhesive properties from Clostridium difficile. | 分子名称: | ABC-type transport system, sugar-family extracellular solute-binding protein | 著者 | Bradshaw, W.J, Kovacs-Simon, A, Harmer, N.J, Michell, S.L, Acharya, K.R. | 登録日 | 2018-09-15 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular features of lipoprotein CD0873: A potential vaccine against the human pathogenClostridioides difficile. J.Biol.Chem., 294, 2019
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3TZ4
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![BU of 3tz4 by Molmil](/molmil-images/mine/3tz4) | Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/S-alpha-chloroisocaproate complex with ADP | 分子名称: | (2S)-2-chloro-4-methylpentanoic acid, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Tso, S.C, Chuang, J.L, Gui, W.J, Wynn, R.M, Li, J, Chuang, D.T. | 登録日 | 2011-09-27 | 公開日 | 2012-10-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase. Proc.Natl.Acad.Sci.USA, 110, 2013
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6K7U
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![BU of 6k7u by Molmil](/molmil-images/mine/6k7u) | Crystal structure of beta-2 microglobulin (beta2m) of Bat (Pteropus Alecto) | 分子名称: | Bat beta-2-microglobulin | 著者 | Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J. | 登録日 | 2019-06-08 | 公開日 | 2019-09-18 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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6HNI
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![BU of 6hni by Molmil](/molmil-images/mine/6hni) | The ligand-bound, closed structure of CD0873, a substrate binding protein with adhesive properties from Clostridium difficile. | 分子名称: | 1,2-ETHANEDIOL, ABC-type transport system, sugar-family extracellular solute-binding protein, ... | 著者 | Bradshaw, W.J, Kovacs-Simon, A, Harmer, N.J, Michell, S.L, Acharya, K.R. | 登録日 | 2018-09-15 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Molecular features of lipoprotein CD0873: A potential vaccine against the human pathogenClostridioides difficile. J.Biol.Chem., 294, 2019
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6HH1
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![BU of 6hh1 by Molmil](/molmil-images/mine/6hh1) | Structure of c-Kit with allosteric inhibitor 3G8 | 分子名称: | Mast/stem cell growth factor receptor Kit,Mast/stem cell growth factor receptor Kit, PHOSPHATE ION, ~{N}-(2,3-dimethylphenyl)-5-(4-pyridin-4-yloxyphenyl)-4~{H}-1,2,4-triazol-3-amine | 著者 | Wrasidlo, W.J, Cheresh, D.A. | 登録日 | 2018-08-24 | 公開日 | 2019-09-18 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of c-Kit with allosteric inhibitor 3G8 To Be Published
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6HQ9
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![BU of 6hq9 by Molmil](/molmil-images/mine/6hq9) | Crystal structure of the Tudor domain of human ERCC6-L2 | 分子名称: | DNA excision repair protein ERCC-6-like 2 | 著者 | Newman, J.A, Gavard, A.E, Nathan, W.J, Pinkas, D.M, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2018-09-24 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.982 Å) | 主引用文献 | Crystal structure of the Tudor domain of human ERCC6-L2 To Be Published
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3XIM
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![BU of 3xim by Molmil](/molmil-images/mine/3xim) | ARGININE RESIDUES AS STABILIZING ELEMENTS IN PROTEINS | 分子名称: | COBALT (II) ION, D-XYLOSE ISOMERASE, sorbitol | 著者 | Mrabet, N.T, Van Denbroek, A, Van Den Brande, I, Stanssens, P, Laroche, Y, Lambeir, A.-M, Matthyssens, G, Jenkins, J, Chiadmi, M, Vantilbeurgh, H, Rey, F, Janin, J, Quax, W.J, Lasters, I, Demaeyer, M, Wodak, S.J. | 登録日 | 1991-05-29 | 公開日 | 1993-04-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Arginine residues as stabilizing elements in proteins. Biochemistry, 31, 1992
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6HNJ
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![BU of 6hnj by Molmil](/molmil-images/mine/6hnj) | The ligand-bound, open structure of CD0873, a substrate binding protein with adhesive properties from Clostridium difficile. | 分子名称: | 1,2-ETHANEDIOL, ABC-type transport system, sugar-family extracellular solute-binding protein, ... | 著者 | Bradshaw, W.J, Kovacs-Simon, A, Harmer, N.J, Michell, S.L, Acharya, K.R. | 登録日 | 2018-09-15 | 公開日 | 2019-08-28 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular features of lipoprotein CD0873: A potential vaccine against the human pathogenClostridioides difficile. J.Biol.Chem., 294, 2019
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3TZ0
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![BU of 3tz0 by Molmil](/molmil-images/mine/3tz0) | Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/S-alpha-chloroisocaproate complex | 分子名称: | (2S)-2-chloro-4-methylpentanoic acid, [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 著者 | Tso, S.C, Chuang, J.L, Gui, W.J, Wynn, R.M, Li, J, Chuang, D.T. | 登録日 | 2011-09-26 | 公開日 | 2012-10-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase. Proc.Natl.Acad.Sci.USA, 110, 2013
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3TSS
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![BU of 3tss by Molmil](/molmil-images/mine/3tss) | TOXIC SHOCK SYNDROME TOXIN-1 TETRAMUTANT, P2(1) CRYSTAL FORM | 分子名称: | TOXIC SHOCK SYNDROME TOXIN-1 | 著者 | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | 登録日 | 1996-12-11 | 公開日 | 1997-12-24 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity. Protein Sci., 6, 1997
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3UCI
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![BU of 3uci by Molmil](/molmil-images/mine/3uci) | Crystal structure of Rhodostomin ARLDDL mutant | 分子名称: | disintegrin | 著者 | Shiu, J.H, Chen, C.Y, Chen, Y.C, Chang, Y.T, Chang, Y.S, Huang, C.H, Chuang, W.J. | 登録日 | 2011-10-27 | 公開日 | 2012-11-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Design of Integrin AlphaVbeta3-Specific Disintegrin for Cancer Therapy To be Published
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3UI7
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![BU of 3ui7 by Molmil](/molmil-images/mine/3ui7) | Discovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophrenia | 分子名称: | 6-methoxy-3,8-dimethyl-4-(morpholin-4-ylmethyl)-1H-pyrazolo[3,4-b]quinoline, MAGNESIUM ION, ZINC ION, ... | 著者 | Yang, S, Smotryski, J, Mcelroy, W, Ho, G, Tulshian, D, Greenlee, W.J, Hodgson, R, Xiao, L, Hruza, A. | 登録日 | 2011-11-04 | 公開日 | 2011-12-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia. Bioorg.Med.Chem.Lett., 22, 2012
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3VJA
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![BU of 3vja by Molmil](/molmil-images/mine/3vja) | Crystal structure of the human squalene synthase | 分子名称: | NICKEL (II) ION, Squalene synthase | 著者 | Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J. | 登録日 | 2011-10-14 | 公開日 | 2012-04-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase J.Biol.Chem., 287, 2012
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3VJB
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![BU of 3vjb by Molmil](/molmil-images/mine/3vjb) | |