6HH1
Structure of c-Kit with allosteric inhibitor 3G8
Summary for 6HH1
Entry DOI | 10.2210/pdb6hh1/pdb |
Descriptor | Mast/stem cell growth factor receptor Kit,Mast/stem cell growth factor receptor Kit, PHOSPHATE ION, ~{N}-(2,3-dimethylphenyl)-5-(4-pyridin-4-yloxyphenyl)-4~{H}-1,2,4-triazol-3-amine, ... (4 entities in total) |
Functional Keywords | c-kit, kinase, allosteric, inhibitor, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 34668.13 |
Authors | Wrasidlo, W.J.,Cheresh, D.A. (deposition date: 2018-08-24, release date: 2019-09-18, Last modification date: 2024-05-15) |
Primary citation | Wrasidlo, W.J.,Cheresh, D.A. Structure of c-Kit with allosteric inhibitor 3G8 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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