8VQX
 
 | |
1B63
 | | MUTL COMPLEXED WITH ADPNP | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, MUTL, ... | | 著者 | Yang, W. | | 登録日 | 1999-01-20 | | 公開日 | 1999-06-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair.
Cell(Cambridge,Mass.), 97, 1999
|
|
1B8D
 | | CRYSTAL STRUCTURE OF A PHYCOUROBILIN-CONTAINING PHYCOERYTHRIN | | 分子名称: | PHYCOERYTHROBILIN, PHYCOUROBILIN, PROTEIN (RHODOPHYTAN PHYCOERYTHRIN (ALPHA CHAIN)), ... | | 著者 | Ritter, S, Hiller, R.G, Wrench, P.M, Welte, W, Diederichs, K. | | 登録日 | 1999-01-29 | | 公開日 | 1999-02-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of a phycourobilin-containing phycoerythrin at 1.90-A resolution.
J.Struct.Biol., 126, 1999
|
|
1A9E
 | | DECAMER-LIKE CONFORMATION OF A NANO-PEPTIDE BOUND TO HLA-B3501 DUE TO NONSTANDARD POSITIONING OF THE C-TERMINUS | | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-35 B*3501 (ALPHA CHAIN), ... | | 著者 | Menssen, R, Orth, P, Ziegler, A, Saenger, W. | | 登録日 | 1998-04-05 | | 公開日 | 1998-10-21 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Decamer-like conformation of a nona-peptide bound to HLA-B*3501 due to non-standard positioning of the C terminus.
J.Mol.Biol., 285, 1999
|
|
721P
 | | THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES | | 分子名称: | H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Krengel, U, Scherer, A, Kabsch, W, Wittinghofer, A, Pai, E.F. | | 登録日 | 1991-06-06 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules.
Cell(Cambridge,Mass.), 62, 1990
|
|
1A9B
 | | DECAMER-LIKE CONFORMATION OF A NANO-PEPTIDE BOUND TO HLA-B3501 DUE TO NONSTANDARD POSITIONING OF THE C-TERMINUS | | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-35 B*3501 (ALPHA CHAIN), ... | | 著者 | Menssen, R, Orth, P, Ziegler, A, Saenger, W. | | 登録日 | 1998-04-03 | | 公開日 | 1998-10-21 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Decamer-like conformation of a nona-peptide bound to HLA-B*3501 due to non-standard positioning of the C terminus.
J.Mol.Biol., 285, 1999
|
|
1AFF
 | | DNA QUADRUPLEX CONTAINING GGGG TETRADS AND (T.A).A TRIADS, NMR, 8 STRUCTURES | | 分子名称: | QUADRUPLEX DNA (5'-D(TP*AP*GP*G)-3') | | 著者 | Kettani, A, Bouaziz, S, Wang, W, Jones, R.A, Patel, D.J. | | 登録日 | 1997-03-06 | | 公開日 | 1997-08-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Bombyx mori single repeat telomeric DNA sequence forms a G-quadruplex capped by base triads.
Nat.Struct.Biol., 4, 1997
|
|
1AHW
 | | A COMPLEX OF EXTRACELLULAR DOMAIN OF TISSUE FACTOR WITH AN INHIBITORY FAB (5G9) | | 分子名称: | IMMUNOGLOBULIN FAB 5G9 (HEAVY CHAIN), IMMUNOGLOBULIN FAB 5G9 (LIGHT CHAIN), TISSUE FACTOR | | 著者 | Huang, M, Syed, R, Stura, E.A, Stone, M.J, Stefanko, R.S, Ruf, W, Edgington, T.S, Wilson, I.A. | | 登録日 | 1997-04-10 | | 公開日 | 1998-02-25 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.5G9 complex.
J.Mol.Biol., 275, 1998
|
|
7UYU
 | | Crystal structure of TYK2 kinase domain in complex with compound 30 | | 分子名称: | 2-(2,6-difluorophenyl)-4-[4-(pyrrolidine-1-carbonyl)anilino]-5H-pyrrolo[3,4-b]pyridin-5-one, Non-receptor tyrosine-protein kinase TYK2, SULFATE ION | | 著者 | Toms, A.V, Leit, S, Greenwood, J.R, Mondal, S, Carriero, S, Dahlgren, M, Harriman, G.C, Kennedy-Smith, J.J, Kapeller, R, Lawson, J.P, Romero, D.L, Shelley, M, Wester, R.T, Westlin, W, Mc Elwee, J.J, Miao, W, Edmondson, S.D, Massee, C.E. | | 登録日 | 2022-05-07 | | 公開日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis.
Bioorg.Med.Chem.Lett., 73, 2022
|
|
7UYR
 | | Crystal structure of TYK2 kinase domain in complex with compound 12 | | 分子名称: | 2-(4-{[2-(2,6-difluorophenyl)-5-oxo-5H-pyrrolo[3,4-d]pyrimidin-4-yl]amino}phenyl)-N-ethylacetamide, Non-receptor tyrosine-protein kinase TYK2 | | 著者 | Toms, A.V, Leit, S, Greenwood, J.R, Mondal, S, Carriero, S, Dahlgren, M, Harriman, G.C, Kennedy-Smith, J.J, Kapeller, R, Lawson, J.P, Romero, D.L, Shelley, M, Wester, R.T, Westlin, W, Mc Elwee, J.J, Miao, W, Edmondson, S.D, Massee, C.E. | | 登録日 | 2022-05-07 | | 公開日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis.
Bioorg.Med.Chem.Lett., 73, 2022
|
|
7UYW
 | | Crystal structure of JAK2 kinase domain in complex with compound 30 | | 分子名称: | 2-(2,6-difluorophenyl)-4-[4-(pyrrolidine-1-carbonyl)anilino]-5H-pyrrolo[3,4-b]pyridin-5-one, Tyrosine-protein kinase JAK2 | | 著者 | Toms, A.V, Leit, S, Greenwood, J.R, Mondal, S, Carriero, S, Dahlgren, M, Harriman, G.C, Kennedy-Smith, J.J, Kapeller, R, Lawson, J.P, Romero, D.L, Shelley, M, Wester, R.T, Westlin, W, Mc Elwee, J.J, Miao, W, Edmondson, S.D, Massee, C.E. | | 登録日 | 2022-05-07 | | 公開日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis.
Bioorg.Med.Chem.Lett., 73, 2022
|
|
7UYT
 | | Crystal structure of TYK2 kinase domain in complex with compound 25 | | 分子名称: | 6-{[(2M)-2-(2-chloro-6-fluorophenyl)-5-oxo-5H-pyrrolo[3,4-b]pyridin-4-yl]amino}-N-ethylpyridine-3-carboxamide, Non-receptor tyrosine-protein kinase TYK2 | | 著者 | Toms, A.V, Leit, S, Greenwood, J.R, Mondal, S, Carriero, S, Dahlgren, M, Harriman, G.C, Kennedy-Smith, J.J, Kapeller, R, Lawson, J.P, Romero, D.L, Shelley, M, Wester, R.T, Westlin, W, Mc Elwee, J.J, Miao, W, Edmondson, S.D, Massee, C.E. | | 登録日 | 2022-05-07 | | 公開日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis.
Bioorg.Med.Chem.Lett., 73, 2022
|
|
1B9U
 | |
1BEN
 | | INSULIN COMPLEXED WITH 4-HYDROXYBENZAMIDE | | 分子名称: | 4-HYDROXYBENZAMIDE, CHLORIDE ION, HUMAN INSULIN, ... | | 著者 | Smith, G.D, Ciszak, E, Pangborn, W. | | 登録日 | 1996-02-15 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A novel complex of a phenolic derivative with insulin: structural features related to the T-->R transition.
Protein Sci., 5, 1996
|
|
1BHY
 | | LOW TEMPERATURE MIDDLE RESOLUTION STRUCTURE OF P64K FROM MASC DATA | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, P64K | | 著者 | Ramin, M, Shepard, W, Fourme, R, Kahn, R. | | 登録日 | 1998-06-10 | | 公開日 | 1998-11-04 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (4.18 Å) | | 主引用文献 | Multiwavelength anomalous solvent contrast (MASC): derivation of envelope structure-factor amplitudes and comparison with model values.
Acta Crystallogr.,Sect.D, 55, 1999
|
|
1B66
 | | 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE | | 分子名称: | 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE, BIOPTERIN, ZINC ION | | 著者 | Ploom, T, Thoeny, B, Yim, J, Lee, S, Nar, H, Leimbacher, W, Huber, R, Richardson, J, Auerbach, G. | | 登録日 | 1999-01-20 | | 公開日 | 1999-04-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic and kinetic investigations on the mechanism of 6-pyruvoyl tetrahydropterin synthase.
J.Mol.Biol., 286, 1999
|
|
1BHW
 | | LOW TEMPERATURE MIDDLE RESOLUTION STRUCTURE OF XYLOSE ISOMERASE FROM MASC DATA | | 分子名称: | XYLOSE ISOMERASE | | 著者 | Ramin, M, Shepard, W, Fourme, R, Kahn, R. | | 登録日 | 1998-06-10 | | 公開日 | 1998-11-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | | 主引用文献 | Multiwavelength anomalous solvent contrast (MASC): derivation of envelope structure-factor amplitudes and comparison with model values.
Acta Crystallogr.,Sect.D, 55, 1999
|
|
1C0L
 | | D-AMINO ACID OXIDASE: STRUCTURE OF SUBSTRATE COMPLEXES AT VERY HIGH RESOLUTION REVEAL THE CHEMICAL REACTTION MECHANISM OF FLAVIN DEHYDROGENATION | | 分子名称: | D-AMINO ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, TRIFLUOROALANINE | | 著者 | Umhau, S, Molla, G, Diederichs, K, Pilone, M.S, Ghisla, S, Welte, W. | | 登録日 | 1999-07-16 | | 公開日 | 2000-11-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation.
Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
1C0I
 | | CRYSTAL STRUCTURE OF D-AMINO ACID OXIDASE IN COMPLEX WITH TWO ANTHRANYLATE MOLECULES | | 分子名称: | 2-AMINOBENZOIC ACID, D-AMINO ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Pollegioni, L, Diederichs, K, Molla, G, Umhau, S, Welte, W, Ghisla, S, Pilone, M.S. | | 登録日 | 1999-07-16 | | 公開日 | 2002-02-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Yeast d-amino Acid oxidase: structural basis of its catalytic properties
J.Mol.Biol., 324, 2002
|
|
1CEW
 | |
4QWP
 | | co-crystal structure of chitosanase OU01 with substrate | | 分子名称: | 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | 著者 | Lyu, Q, Liu, W, Han, B. | | 登録日 | 2014-07-17 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and biochemical insights into the degradation mechanism of chitosan by chitosanase OU01.
Biochim.Biophys.Acta, 1850, 2015
|
|
3L15
 | |
4I6P
 | | Crystal structure of Par3-NTD domain | | 分子名称: | Partitioning defective 3 homolog | | 著者 | Wang, W, Gao, F, Gong, W, Sun, F, Feng, W. | | 登録日 | 2012-11-29 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural insights into the intrinsic self-assembly of par-3 N-terminal domain.
Structure, 21, 2013
|
|
6CIJ
 | | Cryo-EM structure of mouse RAG1/2 HFC complex containing partial HMGB1 linker(3.9 A) | | 分子名称: | CALCIUM ION, DNA (30-MER), DNA (41-MER), ... | | 著者 | Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W. | | 登録日 | 2018-02-24 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
|
|
1WOF
 | | Crystal Structure Of SARS-CoV Mpro in Complex with an Inhibitor N1 | | 分子名称: | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | | 著者 | Yang, H, Bartlam, M, Xue, X, Yang, K, Liang, W, Rao, Z. | | 登録日 | 2004-08-18 | | 公開日 | 2005-08-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
|
|
