1A65
 
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1CX2
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1LPF
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1LH0
 | | Crystal Structure of Salmonella typhimurium OMP Synthase in Complex with MGPRPP and Orotate | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, OMP synthase, ... | | 著者 | Fedorov, A.A, Panneerselvam, K, Shi, W, Grubmeyer, C, Almo, S.C. | | 登録日 | 2002-04-16 | | 公開日 | 2002-05-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of Salmonella typhimurium OMP Synthase in a Complete Substrate Complex.
Biochemistry, 51, 2012
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1K8I
 | | CRYSTAL STRUCTURE OF MOUSE H2-DM | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II H2-M alpha chain, MHC class II H2-M beta 2 chain | | 著者 | Fremont, D.H, Crawford, F, Marrack, P, Hendrickson, W, Kappler, J. | | 登録日 | 2001-10-24 | | 公開日 | 2001-12-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of mouse H2-M.
Immunity, 9, 1998
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1COS
 | | CRYSTAL STRUCTURE OF A SYNTHETIC TRIPLE-STRANDED ALPHA-HELICAL BUNDLE | | 分子名称: | COILED SERINE | | 著者 | Lovejoy, B, Choe, S, Cascio, D, Mcrorie, D.K, Degrado, W, Eisenberg, D. | | 登録日 | 1993-01-22 | | 公開日 | 1993-10-31 | | 最終更新日 | 2019-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of a synthetic triple-stranded alpha-helical bundle.
Science, 259, 1993
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1CZ7
 | | THE CRYSTAL STRUCTURE OF A MINUS-END DIRECTED MICROTUBULE MOTOR PROTEIN NCD REVEALS VARIABLE DIMER CONFORMATIONS | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MICROTUBULE MOTOR PROTEIN NCD | | 著者 | Kozielski, F.K, De Bonis, S, Burmeister, W, Cohen-Addad, C, Wade, R. | | 登録日 | 1999-09-01 | | 公開日 | 1999-11-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The crystal structure of the minus-end-directed microtubule motor protein ncd reveals variable dimer conformations.
Structure Fold.Des., 7, 1999
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1A11
 | | NMR STRUCTURE OF MEMBRANE SPANNING SEGMENT 2 OF THE ACETYLCHOLINE RECEPTOR IN DPC MICELLES, 10 STRUCTURES | | 分子名称: | ACETYLCHOLINE RECEPTOR M2 | | 著者 | Gesell, J.J, Sun, W, Montal, M, Opella, S.J. | | 登録日 | 1997-12-19 | | 公開日 | 1998-04-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy.
Nat.Struct.Biol., 6, 1999
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165D
 | | THE STRUCTURE OF A MISPAIRED RNA DOUBLE HELIX AT 1.6 ANGSTROMS RESOLUTION AND IMPLICATIONS FOR THE PREDICTION OF RNA SECONDARY STRUCTURE | | 分子名称: | DNA/RNA (5'-R(*GP*CP*UP*UP*CP*GP*GP*CP*)-D(*(BRU))-3'), RHODIUM HEXAMINE ION | | 著者 | Cruse, W, Saludjian, P, Biala, E, Strazewski, P, Prange, T, Kennard, O. | | 登録日 | 1994-03-21 | | 公開日 | 1994-08-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structure of a mispaired RNA double helix at 1.6-A resolution and implications for the prediction of RNA secondary structure.
Proc.Natl.Acad.Sci.USA, 91, 1994
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1LIH
 | | THREE-DIMENSIONAL STRUCTURES OF THE LIGAND-BINDING DOMAIN OF THE BACTERIAL ASPARTATE RECEPTOR WITH AND WITHOUT A LIGAND | | 分子名称: | 1,10-PHENANTHROLINE, ASPARTATE RECEPTOR | | 著者 | Kim, S.-H, Scott, W, Yeh, J.I, Prive, G.G, Milburn, M. | | 登録日 | 1995-04-18 | | 公開日 | 1995-09-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Three-dimensional structures of the ligand-binding domain of the bacterial aspartate receptor with and without a ligand.
Science, 254, 1991
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1HL6
 | | A novel mode of RBD-protein recognition in the Y14-mago complex | | 分子名称: | CG8781 PROTEIN, MAGO NASHI PROTEIN | | 著者 | Fribourg, S, Gatfield, D, Yao, W, Izaurralde, E, Conti, E. | | 登録日 | 2003-03-13 | | 公開日 | 2003-05-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A Novel Mode of Rbd-Protein Recognition in the Y14-Mago Complex
Nat.Struct.Biol., 10, 2003
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1MC0
 | | Regulatory Segment of Mouse 3',5'-Cyclic Nucleotide Phosphodiesterase 2A, Containing the GAF A and GAF B Domains | | 分子名称: | 3',5'-cyclic nucleotide phosphodiesterase 2A, CYCLIC GUANOSINE MONOPHOSPHATE | | 著者 | Martinez, S, Wu, A, Glavas, N, Tang, X, Turley, S, Hol, W, Beavo, J. | | 登録日 | 2002-08-04 | | 公開日 | 2002-10-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1MFT
 | | Crystal Structure Of Four-Helix Bundle Model | | 分子名称: | Four-helix bundle model, ZINC ION | | 著者 | Lahr, S.J, Stayrook, S.E, North, B, Kaplan, J, Geremia, S, DeGrado, W. | | 登録日 | 2002-08-13 | | 公開日 | 2004-01-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Analysis and Design of Turns in alpha-Helical Hairpins
J.Mol.Biol., 346, 2005
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8UTL
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9RAT
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8UO7
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5XKM
 | | Crystal structure of human phosphodiesterase 2A in complex with 6-methyl-N-(1-(4-(trifluoromethoxy)phenyl)propyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | | 分子名称: | 6-methyl-N-[(1R)-1-[4-(trifluoromethyloxy)phenyl]propyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide, MAGNESIUM ION, ZINC ION, ... | | 著者 | Oki, H, Kondo, M, Snell, G, Lane, W. | | 登録日 | 2017-05-08 | | 公開日 | 2017-08-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Discovery of an Orally Bioavailable, Brain-Penetrating, in Vivo Active Phosphodiesterase 2A Inhibitor Lead Series for the Treatment of Cognitive Disorders.
J. Med. Chem., 60, 2017
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5XBO
 | | Lanthanoid tagging via an unnatural amino acid for protein structure characterization | | 分子名称: | Polyubiquitin-B, TERBIUM(III) ION, UV excision repair protein RAD23 homolog A | | 著者 | Jiang, W, Gu, X, Dong, X, Tang, C. | | 登録日 | 2017-03-21 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Lanthanoid tagging via an unnatural amino acid for protein structure characterization
J. Biomol. NMR, 67, 2017
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5YBF
 | | Crystal structure of the GluA2o LBD in complex with glutamate and HBT1 | | 分子名称: | 2-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanoylamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, ACETATE ION, GLUTAMIC ACID, ... | | 著者 | Sogabe, S, Igaki, S, Hirokawa, A, Zama, Y, Lane, W, Snell, G. | | 登録日 | 2017-09-04 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | HBT1, a Novel AMPA Receptor Potentiator with Lower Agonistic Effect, Avoided Bell-Shaped Response in In Vitro BDNF Production.
J. Pharmacol. Exp. Ther., 364, 2018
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5YAO
 | | The complex structure of SZ529 and expoxid | | 分子名称: | (1R,5S)-6-oxabicyclo[3.1.0]hexane, Limonene-1,2-epoxide hydrolase, SODIUM ION | | 著者 | Lian, W, Sun, Z.T, Zhou, J.H, Reetz, M.T. | | 登録日 | 2017-09-01 | | 公開日 | 2018-06-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.611 Å) | | 主引用文献 | Structural and Computational Insight into the Catalytic Mechanism of Limonene Epoxide Hydrolase Mutants in Stereoselective Transformations
J. Am. Chem. Soc., 140, 2018
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5YBG
 | | Crystal structure of the GluA2o LBD in complex with glutamate and LY451395 | | 分子名称: | ACETATE ION, GLUTAMIC ACID, GLYCEROL, ... | | 著者 | Sogabe, S, Igaki, S, Hirokawa, A, Zama, Y, Lane, W, Snell, G. | | 登録日 | 2017-09-04 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | HBT1, a Novel AMPA Receptor Potentiator with Lower Agonistic Effect, Avoided Bell-Shaped Response in In Vitro BDNF Production.
J. Pharmacol. Exp. Ther., 364, 2018
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5ZG3
 | | Crystal structure of the GluA2o LBD in complex with glutamate and TAK-137 | | 分子名称: | 9-(4-phenoxyphenyl)-3,4-dihydro-2H-2lambda~6~-pyrido[2,1-c][1,2,4]thiadiazine-2,2-dione, ACETATE ION, GLUTAMIC ACID, ... | | 著者 | Sogabe, S, Igaki, S, Hirokawa, A, Zama, Y, Lane, W, Snell, G. | | 登録日 | 2018-03-07 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | TAK-137, an AMPA-R potentiator with little agonistic effect, has a wide therapeutic window.
Neuropsychopharmacology, 44, 2019
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5WDH
 | | Motor domain of human kinesin family member C1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIFC1, MAGNESIUM ION, ... | | 著者 | Zhu, H, Tempel, W, He, H, Shen, Y, Wang, J, Brothers, G, Landry, R, Arrowsmith, C.H, Edwards, A.M, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2017-07-05 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.248 Å) | | 主引用文献 | Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.
Sci Rep, 7, 2017
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5WDE
 | | Crystal structure of the KIFC3 motor domain in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIFC3, MAGNESIUM ION, ... | | 著者 | Shen, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2017-07-05 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.
Sci Rep, 7, 2017
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5ZG2
 | | Crystal structure of the GluA2o LBD in complex with ZK200775 and Compound-2 | | 分子名称: | 9-(4-~{tert}-butylphenyl)-3,4-dihydropyrido[2,1-c][1,2,4]thiadiazine 2,2-dioxide, ACETATE ION, GLYCEROL, ... | | 著者 | Sogabe, S, Igaki, S, Hirokawa, A, Zama, Y, Lane, W, Snell, G. | | 登録日 | 2018-03-07 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | TAK-137, an AMPA-R potentiator with little agonistic effect, has a wide therapeutic window.
Neuropsychopharmacology, 44, 2019
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